$144 Cheap American Airlines flights Jacksonville (JAX) to Key West (EYW)

Scoring cheap one-way American Airlines flights from JAX to EYW from $144 on Expedia is easy — just filter by “Price (lowest to highest).” Or check out our budget-friendly return fares from $287 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Key West tend to be cheaper in the low-season months of September and August. Whether you need a return or one-way ticket, you could land a better deal then.

To find cheap American Airlines fares from Jacksonville Intl. Airport (JAX) to Key West Intl. Airport (EYW), start searching one to three months before your planned departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the overall cost. Sunday is usually the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your flight on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Fill in your dates, hit search and select “Nonstop” on Expedia to find any direct flights from JAX to EYW with American Airlines or another carrier.

Sort your results by “Early Morning” and “Morning” to see the earliest flights from JAX to EYW. Heading off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Key West Intl. Airport (EYW) is the main Key West gateway for American Airlines flights from Jacksonville Intl. Airport (JAX).

Depending on your ticket type, a fee will generally apply if you cancel or change your booking more than 24 hours after it’s confirmed. To find flexible plane tickets, select our “Changes included” and “No cancel fee” boxes while searching for flights. For additional information on changing or canceling your reservation, visit “Trips,” select your flight and tick “Manage Booking.”