$100 Cheap American Airlines flights Harrisburg (MDT) to Fort Myers (RSW)

Finding cheap one-way American Airlines flights from MDT to RSW from $100 on Expedia is easy — just filter by “Price (lowest to highest).” Or check out our affordable round-trip fares from $199 for your next exciting vacation.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Fort Myers are often more affordable in the off-peak months of August and September. Whether you’re searching for a one-way or a return ticket, you could land a better deal then.

Look for affordable American Airlines flights from Harrisburg Intl. Airport (MDT) to Southwest Florida Intl. Airport (RSW) one to three months ahead of your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and itinerary, the ideal day to book a domestic flight is usually Sunday and the most expensive is typically Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Simply enter your dates, press search and check “Nonstop” on Expedia to browse any direct flights from MDT to RSW with American Airlines or another carrier.

Sort your results by “Early Morning” and “Morning” to browse the earliest departures from MDT to RSW. Taking off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Harrisburg Intl. Airport (MDT) to Fort Myers come in to Southwest Florida Intl. Airport (RSW). This is the main entry point to this destination.

Depending on your ticket type, a fee may apply if you cancel or change your flight more than 24 hours after confirmation. To find plane tickets with more flexibility, select our “No cancel fee” or “Changes included” filter while searching for flights. To learn more about changing or canceling your reservation, head to “Trips,” select your flight and click on “Manage Booking.”