$100 Cheap American Airlines flights Harrisburg (MDT) to Myrtle Beach (MYR)

Finding cheap one-way American Airlines flights from MDT to MYR from $100 on Expedia is a cinch — just filter by “Price (lowest to highest).” Or check out our affordable return fares from $199 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Myrtle Beach tend to be more affordable in the low-season months of January and November. Whether you’re after a one-way or round-trip ticket, you could land a better deal then.

Start searching one to three months ahead of your travel date to find cheaper fares on American Airlines flights from Harrisburg Intl. Airport (MDT) to Myrtle Beach Intl. Airport (MYR). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic flights.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Click on the “Nonstop” filter when looking for direct American Airlines flights from MDT to MYR. It’s also an easy way to compare other airlines offering the same direct route.

Sort your results by “Early Morning” and “Morning” to find the earliest departures from MDT to MYR. Jetting off early means you’re less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Harrisburg Intl. Airport (MDT) to Myrtle Beach land at Myrtle Beach Intl. Airport (MYR). This is the main gateway to this destination.

Typically, you can cancel or modify your flight, although there may be additional charges if you made your booking over 24 hours ago. Prefer to keep your options open? Use Expedia’s “Changes included” and “No cancel fee” filters to find flights that won’t penalize you if you have to adjust your plans. To update your booking, head to “Trips,” select your flight and click on “Manage Booking” for more details.