$125 Cheap American Airlines flights Harrisburg (MDT) to Orange County (SNA)

Make use of the “Price (lowest to highest)” filter on Expedia to search for cheap American Airlines round-trip flights from $279 from MDT to SNA. Affordable one-way tickets from $125 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to get away to Santa Ana with American Airlines. You could also find great deals on one-way and return fares in April.

Search for cheap American Airlines flights from Harrisburg Intl. Airport (MDT) to John Wayne Airport (SNA) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare type and itinerary, the ideal day to book a domestic flight is generally Sunday and the most expensive day tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Select our “Nonstop” filter when searching for direct American Airlines flights from MDT to SNA. It’s also an easy way to compare other carriers offering the same nonstop journey.

Sort your results by “Early Morning” and “Morning” to find the earliest flights from MDT to SNA. Jetting off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

John Wayne Airport (SNA) is the main Santa Ana hub for American Airlines flights from Harrisburg Intl. Airport (MDT).

Changes are typically free within 24 hours of making a booking, but your airline may charge a fee after that time. For more details about altering your reservation, head to your “Trips,” select your flight and click on “Manage Booking.” If you want the freedom to change your itinerary without being charged, apply the “Changes included” and “No cancel fee” filters when organizing your trip.