$105 Cheap American Airlines flights Milwaukee (MKE) to McAllen (MFE)

Landing cheap one-way American Airlines flights from MKE to MFE from $105 on Expedia is easy — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly return fares from $239 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

October is one of the least expensive months to jet off to McAllen with American Airlines. You could also find great prices on one-way and round-trip fares in January.

To find cheap American Airlines fares from General Mitchell Intl. Airport (MKE) to Miller Intl. Airport (MFE), start searching one to three months before your planned departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the price you pay. Sunday is generally the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Use the “Nonstop” filter when browsing for direct American Airlines flights from MKE to MFE. It’s also a great way to compare other airlines servicing the same nonstop route.

To find the earliest departures from MKE to MFE with American Airlines, filter your results by “Morning” and “Early Morning.” Choosing an early flight generally means you’re less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Miller Intl. Airport (MFE) is the main McAllen hub for American Airlines flights from General Mitchell Intl. Airport (MKE).

Depending on your ticket type, a fee may apply if you change or cancel your booking more than 24 hours after it’s confirmed. To secure flexible fares, select our “Changes included” and “No cancel fee” boxes while searching for flights. To learn more about canceling or modifying your reservation, visit “Trips,” select your flight and tick “Manage Booking.”