$143 Cheap American Airlines flights Detroit (DTW) to Amarillo (AMA)

Make use of the “Price (lowest to highest)” filter on Expedia to search for cheap American Airlines round-trip flights from $285 from DTW to AMA. Affordable one-way tickets from $143 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to Amarillo are generally more affordable in the quieter months of February and January. Whether you’re in search of a one-way or round-trip ticket, you could score a better deal then.

Start searching one to three months before your departure to score cheaper fares on American Airlines flights from Detroit Metropolitan Wayne County Airport (DTW) to Rick Husband Amarillo Intl. Airport (AMA). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing spot on, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To figure out if there’s a direct trip from DTW to AMA with American Airlines or other airlines, check the “Nonstop” filter when searching for tickets.

Filter your results by “Morning” and “Early Morning” to find the earliest departures from DTW to AMA. Heading off early means you’re 20% less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Rick Husband Amarillo Intl. Airport (AMA) is the main Amarillo gateway for American Airlines flights from Detroit Metropolitan Wayne County Airport (DTW).

Typically, you can cancel or reschedule your flight, although there may be additional charges if you booked more than 24 hours ago. Need flexible options? Use Expedia’s “No cancel fee” or “Changes included” filter to find flights that won’t penalize you if you need to adjust your plans. To update your booking, visit “Trips,” select your flight and click on “Manage Booking” for further information.