$209 Cheap Alaska Airlines flights Portland (PDX) to Des Moines (DSM)

Finding cheap one-way Alaska Airlines flights from PDX to DSM from $209 on Expedia is a cinch — just filter by “Price (lowest to highest).” Alternatively, check out our budget-friendly round-trip fares from $417 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the least expensive months to jet away to Des Moines with Alaska Airlines. You could also find excellent prices on return and one-way fares in December.

Begin your search one to three months ahead of your departure date to score cheaper fares on Alaska Airlines flights from Portland Intl. Airport (PDX) to Des Moines Intl. Airport (DSM). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Nail your timing, and you can enjoy significant savings on domestic trips.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

To find out if there’s a direct journey from PDX to DSM with Alaska Airlines or any other carriers, check the “Nonstop” filter when browsing for flights.

To find the earliest departures from PDX to DSM with Alaska Airlines, sort your results by “Early Morning” and “Morning.” Choosing an early flight usually means you’ll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Des Moines Intl. Airport (DSM) is the primary Des Moines hub for Alaska Airlines flights from Portland Intl. Airport (PDX).

With an excellent in-flight experience and a rewarding loyalty program, Alaska Airlines is the leading choice for many passengers flying from PDX to DSM. What’s more, if you’re a Mileage Plan and One Key™ member booking with Expedia, you could earn OneKeyCash™* on eligible flights on top of your airline miles, which can be spent on future travel purchases.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

Depending on the ticket type you purchased, a fee may apply if you cancel or change your booking more than 24 hours after it’s been confirmed. To find plane tickets with more flexibility, select our “No cancel fee” or “Changes included” filter when looking for flights. For additional information on modifying or canceling your reservation, head to “Trips,” select your flight and click on “Manage Booking.”