$228 Cheap Flights from Quito (UIO) to Santiago (SCL)

View $228 flight on Mon, Aug 4, 2025Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Santiago Intl. Airport (SCL)

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Find available prices by choosing your travel dates.

Cheap Flights from Quito to Santiago (UIO-SCL)

Prices were available within the past 7 days and start at $228 for one-way flights and $363 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Wed, Aug 27 - Sun, Sep 7
UIO
Quito
SCL
Santiago
$363 Roundtrip, found 1 day ago
$363
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Wed, Aug 27 from Quito to Santiago, returning Sun, Sep 7, priced at $363 found 1 day ago
Jetsmart SPA
Wed, Oct 1 - Sun, Oct 19
UIO
Quito
SCL
Santiago
$373 Roundtrip, found 1 day ago
$373
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Wed, Oct 1 from Quito to Santiago, returning Sun, Oct 19, priced at $373 found 1 day ago
Jetsmart SPA
Sun, Aug 24 - Sun, Sep 7
UIO
Quito
SCL
Santiago
$394 Roundtrip, found 1 day ago
$394
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Sun, Aug 24 from Quito to Santiago, returning Sun, Sep 7, priced at $394 found 1 day ago
Jetsmart SPA
Wed, Aug 27 - Fri, Sep 12
UIO
Quito
SCL
Santiago
$399 Roundtrip, found 1 day ago
$399
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Wed, Aug 27 from Quito to Santiago, returning Fri, Sep 12, priced at $399 found 1 day ago
Jetsmart SPA
Wed, Oct 1 - Wed, Oct 15
UIO
Quito
SCL
Santiago
$405 Roundtrip, found 1 day ago
$405
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Wed, Oct 1 from Quito to Santiago, returning Wed, Oct 15, priced at $405 found 1 day ago
Jetsmart SPA
Fri, Sep 12 - Wed, Sep 24
UIO
Quito
SCL
Santiago
$406 Roundtrip, found 1 day ago
$406
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Fri, Sep 12 from Quito to Santiago, returning Wed, Sep 24, priced at $406 found 1 day ago
Jetsmart SPA
Wed, May 7 - Wed, Aug 27
UIO
Quito
SCL
Santiago
$412 Roundtrip, found 4 hours ago
$412
Roundtrip
found 4 hours ago
Select Jetsmart SPA flight, departing Wed, May 7 from Quito to Santiago, returning Wed, Aug 27, priced at $412 found 4 hours ago
avianca
Sun, Jun 8 - Tue, Jun 17
UIO
Quito
SCL
Santiago
$463 Roundtrip, found 10 hours ago
$463
Roundtrip
found 10 hours ago
Select avianca flight, departing Sun, Jun 8 from Quito to Santiago, returning Tue, Jun 17, priced at $463 found 10 hours ago
Copa
Sun, Jun 8 - Tue, Jun 17
UIO
Quito
SCL
Santiago
$472 Roundtrip, found 10 hours ago
$472
Roundtrip
found 10 hours ago
Select Copa flight, departing Sun, Jun 8 from Quito to Santiago, returning Tue, Jun 17, priced at $472 found 10 hours ago
LATAM Airlines Group
Wed, Aug 6 - Tue, Aug 12
UIO
Quito
SCL
Santiago
$623 Roundtrip, just found
$623
Roundtrip
just found
Select LATAM Airlines Group flight, departing Wed, Aug 6 from Quito to Santiago, returning Tue, Aug 12, priced at $623 just found

Frequently asked questions

How much does a flight from Mariscal Sucre Intl. Airport (UIO) to Arturo Merino Benitez Airport (SCL) cost?
Discover the latest flight deals from UIO to SCL by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from UIO to SCL?
The cheapest flights from UIO to SCL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from UIO to SCL?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from UIO to SCL. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Mariscal Sucre Intl. Airport (UIO) to Arturo Merino Benitez Airport (SCL)?
Direct flights from Mariscal Sucre Intl. Airport (UIO) to Arturo Merino Benitez Airport (SCL) aren’t available daily, so you’ll have to take a flight with a layover. Explore your options with Expedia’s filter tool. Enter your dates and select either “1 Stop” or “2+ Stops.”
What day of the week has the most flights from UIO to SCL?
You’ll typically find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mariscal Sucre Intl. Airport (UIO) to Arturo Merino Benitez Airport (SCL)?
To avoid potential delays on the Mariscal Sucre Intl. Airport (UIO) to Arturo Merino Benitez Airport (SCL) route, fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Mariscal Sucre Intl. Airport (UIO) to Arturo Merino Benitez Airport (SCL) last-minute?
Holding off until just before your departure to book a flight from UIO to SCL generally means paying more. While you might find some last-minute discounts, there’s no guarantee. Keep your travel plans flexible to maximize your chances of landing a bargain.
Is it cheaper to book an UIO to SCL flight and hotel package?
Opting for an UIO to SCL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Select from our wide range of accommodations and then add activities, flights and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mariscal Sucre Intl. Airport (UIO) to Arturo Merino Benitez Airport (SCL)?
If you booked your UIO to SCL flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for further details.
*Available to One Key members.