$27 Cheap Flights from Santiago (SCL) to La Serena (LSC)

View $27 flight on Thu, Oct 23, 2025Opens in a new window

Popular airlines from Santiago Intl. Airport (SCL) to La Serena (LSC-La Florida)

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Cheap Flights from Santiago to La Serena (SCL-LSC)

Prices were available within the past 7 days and start at $27 for one-way flights and $53 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Sat, Oct 11 - Sat, Oct 18
SCL
Santiago
LSC
La Serena
$53 Roundtrip, found 23 hours ago
$53
Roundtrip
found 23 hours ago
Select SKY AIRLINE flight, departing Sat, Oct 11 from Santiago to La Serena, returning Sat, Oct 18, priced at $53 found 23 hours ago
SKY AIRLINE
Sat, Sep 27 - Wed, Oct 1
SCL
Santiago
LSC
La Serena
$57 Roundtrip, found 1 day ago
$57
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Sat, Sep 27 from Santiago to La Serena, returning Wed, Oct 1, priced at $57 found 1 day ago
SKY AIRLINE
Thu, Oct 23 - Sun, Oct 26
SCL
Santiago
LSC
La Serena
$58 Roundtrip, found 21 hours ago
$58
Roundtrip
found 21 hours ago
Select SKY AIRLINE flight, departing Thu, Oct 23 from Santiago to La Serena, returning Sun, Oct 26, priced at $58 found 21 hours ago
SKY AIRLINE
Fri, Oct 24 - Tue, Oct 28
SCL
Santiago
LSC
La Serena
$60 Roundtrip, found 1 day ago
$60
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Fri, Oct 24 from Santiago to La Serena, returning Tue, Oct 28, priced at $60 found 1 day ago
SKY AIRLINE
Sun, Jan 4 - Thu, Jan 8
SCL
Santiago
LSC
La Serena
$61 Roundtrip, found 1 day ago
$61
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Sun, Jan 4 from Santiago to La Serena, returning Thu, Jan 8, priced at $61 found 1 day ago
SKY AIRLINE
Wed, Nov 12 - Sun, Nov 16
SCL
Santiago
LSC
La Serena
$62 Roundtrip, just found
$62
Roundtrip
just found
Select SKY AIRLINE flight, departing Wed, Nov 12 from Santiago to La Serena, returning Sun, Nov 16, priced at $62 just found
LATAM Airlines Group
Sat, Oct 11 - Sat, Oct 18
SCL
Santiago
LSC
La Serena
$63 Roundtrip, found 23 hours ago
$63
Roundtrip
found 23 hours ago
Select LATAM Airlines Group flight, departing Sat, Oct 11 from Santiago to La Serena, returning Sat, Oct 18, priced at $63 found 23 hours ago
SKY AIRLINE
Thu, Nov 20 - Wed, Dec 10
SCL
Santiago
LSC
La Serena
$64 Roundtrip, found 21 hours ago
$64
Roundtrip
found 21 hours ago
Select SKY AIRLINE flight, departing Thu, Nov 20 from Santiago to La Serena, returning Wed, Dec 10, priced at $64 found 21 hours ago
SKY AIRLINE
Mon, Sep 22 - Sat, Sep 27
SCL
Santiago
LSC
La Serena
$65 Roundtrip, found 6 days ago
$65
Roundtrip
found 6 days ago
Select SKY AIRLINE flight, departing Mon, Sep 22 from Santiago to La Serena, returning Sat, Sep 27, priced at $65 found 6 days ago
Jetsmart SPA
Sat, Oct 11 - Sat, Oct 18
SCL
Santiago
LSC
La Serena
$67 Roundtrip, found 23 hours ago
$67
Roundtrip
found 23 hours ago
Select Jetsmart SPA flight, departing Sat, Oct 11 from Santiago to La Serena, returning Sat, Oct 18, priced at $67 found 23 hours ago

Find the cheapest month to fly from Santiago (SCL) to La Serena (LSC)

May is typically the cheapest month to fly

From $35 - $85 per traveler.

Alternative airports near La Serena

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to La Florida LSC. Cheapest and Closest option available. Average driving time to city center is 7 minutes. Flights from $64
LSC
La Florida
CheapestClosest
Average driving time to city center7 min
Flights from $64
Flights from Santiago (SCL) to La Serena (LSC)
Origin airport
Arturo Merino Benitez
Destination airport
La Florida
Airlines serving
Jetsmart SPA, LATAM Airlines Group, SKY AIRLINE
Roundtrip price
$53
Distance
241 mi
Average flight time
1 hour 7 mins

Santiago to La Serena Flights

The cheapest times to fly from Santiago to La Serena

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Santiago to La Serena are during the month of October. You can find some of the cheapest flights from Santiago to La Serena with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Santiago to La Serena

Sunday is one of the best days to book for cheap flights from Santiago to La Serena: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Santiago to La Serena

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Santiago to La Serena in 2025. You can also book with separate airlines for your outbound and return journeys, from $27 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Santiago to La Serena flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Santiago to La Serena airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC) cost?
Snag a cheap one-way flight from $27 or cheap return flight from $53 from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
The cheapest month to fly from SCL to LSC is October, when demand is low. Off-peak season is generally when better flight deals are available between these airports.
Which airlines fly direct from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
Skip the stopovers and travel straight from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC) with 3 airlines, including:

  • LATAM Airlines
  • Sky Airline
  • JetSMART

What is the cheapest airline that flies from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
While prices can vary depending on your travel dates, budget airlines like LATAM Airlines and Sky Airline are typically the cheapest options for flights between Arturo Merino Benitez Airport (SCL) and La Florida Airport (LSC). Use Expedia's search tool to compare carriers and find the one that has the lowest fare for your SCL to LSC flight.
How many flights per day from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
Each day on average, 8 nonstop flights operate from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC). Pick the departure time that best fits your itinerary.
What are the most popular departure times for flights from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
More travelers fly between SCL and LSC at 7 AM than at any other point in the day. Looking to skip the crowds? Try choosing a quieter departure window and there's a chance you'll save on your ticket as well.
What day of the week has the most flights from SCL to LSC?
Fly on a Monday if you're looking for the biggest selection of flights from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC).
What is the earliest flight from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
Hop on the earliest flight at around 7:47AM UTC-3, departing from Arturo Merino Benitez Airport (SCL). You'll be flying for approximately 1h 8m, arriving at La Florida Airport (LSC) at approximately 8:55AM UTC-3.
How long does it take to fly from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
The average flight duration from SCL to LSC is 1 hour and 7 minutes, covering a total distance of 240 mi.
What airline has the least delays from SCL to LSC?
LATAM Airlines has the strongest track record for on-time direct flights from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC), with an on-time score of 80%. Use the Expedia App to view your flight schedule before you take off and get real-time alerts about any trip changes.
What is the best time to fly from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
To touch down at La Florida Airport (LSC) on schedule, opt for a flight that takes off from Arturo Merino Benitez Airport (SCL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for La Serena from Arturo Merino Benitez Airport (SCL)?
Compare your flight options from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC). This is the only La Serena airport you can arrive at if you're taking a direct flight.
Is it cheaper to buy a plane ticket from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC) last-minute?
Holding off until just before your trip to book your flight from SCL to LSC generally means paying more. Although you may find some last-minute deals, they aren't always guaranteed. Be flexible with your itinerary to boost your chances of scoring a bargain.
Is it cheaper to book a SCL to LSC flight and hotel package?
Opting for a SCL to LSC flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Choose from our wide range of hotels and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Arturo Merino Benitez Airport (SCL) to La Florida Airport (LSC)?
In most instances, you can cancel or reschedule your SCL to LSC flight. However, there may be additional charges, especially if you booked more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you need further details, head to our Customer Service portal.

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*Available to One Key members.