$244 Cheap Flights from Panama City (PTY) to Quito (UIO)

View $244 flight on Sun, Aug 17, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)

Find available prices by choosing your travel dates.

Cheap Flights from Panama City to Quito (PTY-UIO)

Prices were available within the past 7 days and start at $244 for one-way flights and $409 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Wed, May 28 - Sun, Jun 1
PTY
Panama City
UIO
Quito
$409 Roundtrip, found 2 days ago
$409
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, May 28 from Panama City to Quito, returning Sun, Jun 1, priced at $409 found 2 days ago
Copa
Thu, Jun 19 - Thu, Jun 26
PTY
Panama City
UIO
Quito
$417 Roundtrip, found 4 hours ago
$417
Roundtrip
found 4 hours ago
Select Copa flight, departing Thu, Jun 19 from Panama City to Quito, returning Thu, Jun 26, priced at $417 found 4 hours ago
Copa
Fri, Jun 20 - Sat, Jun 28
PTY
Panama City
UIO
Quito
$426 Roundtrip, found 1 day ago
$426
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Jun 20 from Panama City to Quito, returning Sat, Jun 28, priced at $426 found 1 day ago
Copa
Wed, May 28 - Sun, Jun 1
PTY
Panama City
UIO
Quito
$453 Roundtrip, found 2 days ago
$453
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, May 28 from Panama City to Quito, returning Sun, Jun 1, priced at $453 found 2 days ago
Copa
Thu, May 1 - Sat, May 3
PTY
Panama City
UIO
Quito
$460 Roundtrip, found 6 hours ago
$460
Roundtrip
found 6 hours ago
Select Copa flight, departing Thu, May 1 from Panama City to Quito, returning Sat, May 3, priced at $460 found 6 hours ago
Copa
Mon, May 12 - Sat, May 17
PTY
Panama City
UIO
Quito
$461 Roundtrip, found 3 days ago
$461
Roundtrip
found 3 days ago
Select Copa flight, departing Mon, May 12 from Panama City to Quito, returning Sat, May 17, priced at $461 found 3 days ago
Copa
Wed, Aug 6 - Fri, Aug 8
PTY
Panama City
UIO
Quito
$464 Roundtrip, found 4 days ago
$464
Roundtrip
found 4 days ago
Select Copa flight, departing Wed, Aug 6 from Panama City to Quito, returning Fri, Aug 8, priced at $464 found 4 days ago
Copa
Sun, Jun 8 - Mon, Jun 23
PTY
Panama City
UIO
Quito
$469 Roundtrip, found 16 hours ago
$469
Roundtrip
found 16 hours ago
Select Copa flight, departing Sun, Jun 8 from Panama City to Quito, returning Mon, Jun 23, priced at $469 found 16 hours ago
Copa
Fri, Jun 20 - Mon, Jun 23
PTY
Panama City
UIO
Quito
$478 Roundtrip, found 1 day ago
$478
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Jun 20 from Panama City to Quito, returning Mon, Jun 23, priced at $478 found 1 day ago
avianca
Tue, Aug 26 - Sat, Sep 6
PTY
Panama City
UIO
Quito
$536 Roundtrip, found 1 hour ago
$536
Roundtrip
found 1 hour ago
Select avianca flight, departing Tue, Aug 26 from Panama City to Quito, returning Sat, Sep 6, priced at $536 found 1 hour ago
Flights from Panama City (PTY) to Quito (UIO)
Origin airport
Tocumen Intl.
Destination airport
Mariscal Sucre Intl.
Airlines serving
Copa, avianca
Roundtrip price
$408
Distance
638 mi

Panama City to Quito Flights

The cheapest times to fly from Panama City to Quito

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Quito are during the month of May. You can find some of the cheapest flights from Panama City to Quito with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Quito

Sunday is one of the best days to book for cheap flights from Panama City to Quito: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Quito

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Quito in 2025. You can also book with separate airlines for your outbound and return journeys, from $244 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Quito flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Quito airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) cost?
Discover the latest flight deals from PTY to UIO by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PTY to UIO?
The cheapest flights from PTY to UIO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
When jetting out of Tocumen Intl. Airport (PTY), you can jump on a nonstop flight to Mariscal Sucre Intl. Airport (UIO) with Copa Airlines.
What is the cheapest airline that flies from PTY to UIO?
With prices as low as $558 for a one-way journey from PTY to UIO, Copa is currently the cheapest carrier for this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PTY on July 3 2025. Prices were last updated on April 26 2025 and have not changed since.
How many flights per day from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
With, on average, 4 nonstop flights that operate from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) each day, you’ll be on your way in no time.
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
More travelers fly between PTY and UIO at 6 PM than at any other time of day. Rather skip the crowds? Travel outside of rush hours and you could save on your fare as well.
What day of the week has the most flights from PTY to UIO?
Friday has the most flights from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO). Consider leaving on this day and you’ll have a greater chance of finding a schedule that works for you.
What is the earliest flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
Catch the earliest flight at around 9:47AM UTC-5, heading out of Tocumen Intl. Airport (PTY). You’ll be traveling for approximately 2h 4m, arriving at Mariscal Sucre Intl. Airport (UIO) at approximately 11:51AM UTC-5.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
The average flight time from PTY to UIO is 2 hours and 4 minutes, covering a distance of 640 mi.
What airline has the least delays from PTY to UIO?
With 92% of journeys generally arriving on schedule, Copa Airlines has the best on-time performance for direct flights from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO). To keep track of your flight status and receive notifications if anything changes, simply head to the Expedia App.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
Opt for a flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) that takes off before 3 PM to reduce the risk of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Quito from Tocumen Intl. Airport (PTY)?
Compare your flight options from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO). This is the only airport in Quito you can arrive at if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO) last-minute?
Last-minute bookings from PTY to UIO are typically more expensive. To lock in the best prices, start searching for flights ahead of time. That said, if you’re flexible with your travel dates, it’s possible to find a cheap ticket right before your trip.
Is it cheaper to book a PTY to UIO flight and hotel package?
You’ll typically save money by booking a PTY to UIO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one place. After choosing your ideal flights and accommodations, consider adding extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Mariscal Sucre Intl. Airport (UIO)?
Typically, it’s possible to cancel or reschedule your PTY to UIO flight. However, if the booking was made more than 24 hours ago, additional fees may apply. Refer to your airline’s policies in your itinerary to see what changes are possible and whether any costs are involved. You’ll also find more details on our Customer Service portal.

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*Available to One Key members.