$540 Cheap Flights from Panama City (PTY) to Porto (OPO)

View $540 flight on Tue, Jul 22, 2025Opens in a new window

  • Plan, book, fly with confidence

  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash
    Learn about One Key
Find available prices by choosing your travel dates.

Cheap Flights from Panama City to Porto (PTY-OPO)

Prices were available within the past 7 days and start at $540 for one-way flights and $755 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Europa
Sat, May 24 - Fri, Jun 6
PTY
Panama City
OPO
Porto
$755 Roundtrip, found 2 days ago
$755
Roundtrip
found 2 days ago
Select Air Europa flight, departing Sat, May 24 from Panama City to Porto, returning Fri, Jun 6, priced at $755 found 2 days ago
Air Europa
Sun, Jun 8 - Thu, Jun 12
PTY
Panama City
OPO
Porto
$766 Roundtrip, found 6 days ago
$766
Roundtrip
found 6 days ago
Select Air Europa flight, departing Sun, Jun 8 from Panama City to Porto, returning Thu, Jun 12, priced at $766 found 6 days ago
Air Europa
Sun, May 18 - Tue, Jun 3
PTY
Panama City
OPO
Porto
$788 Roundtrip, found 2 days ago
$788
Roundtrip
found 2 days ago
Select Air Europa flight, departing Sun, May 18 from Panama City to Porto, returning Tue, Jun 3, priced at $788 found 2 days ago
Air Europa
Sun, Jun 8 - Sat, Jun 14
PTY
Panama City
OPO
Porto
$788 Roundtrip, found 19 hours ago
$788
Roundtrip
found 19 hours ago
Select Air Europa flight, departing Sun, Jun 8 from Panama City to Porto, returning Sat, Jun 14, priced at $788 found 19 hours ago
Air Europa
Sun, Jun 8 - Sat, Jun 14
PTY
Panama City
OPO
Porto
$796 Roundtrip, found 19 hours ago
$796
Roundtrip
found 19 hours ago
Select Air Europa flight, departing Sun, Jun 8 from Panama City to Porto, returning Sat, Jun 14, priced at $796 found 19 hours ago
Air Europa
Sun, May 18 - Sat, May 31
PTY
Panama City
OPO
Porto
$798 Roundtrip, found 2 days ago
$798
Roundtrip
found 2 days ago
Select Air Europa flight, departing Sun, May 18 from Panama City to Porto, returning Sat, May 31, priced at $798 found 2 days ago
Iberia
Mon, Feb 2 - Sun, Feb 8
PTY
Panama City
OPO
Porto
$841 Roundtrip, found 1 day ago
$841
Roundtrip
found 1 day ago
Select Iberia flight, departing Mon, Feb 2 from Panama City to Porto, returning Sun, Feb 8, priced at $841 found 1 day ago
KLM
Mon, May 12 - Fri, May 23
PTY
Panama City
OPO
Porto
$919 Roundtrip, found 2 days ago
$919
Roundtrip
found 2 days ago
Select KLM flight, departing Mon, May 12 from Panama City to Porto, returning Fri, May 23, priced at $919 found 2 days ago
United
Thu, May 29 - Wed, Jun 18
PTY
Panama City
OPO
Porto
$1,096 Roundtrip, found 2 days ago
$1,096
Roundtrip
found 2 days ago
Select United flight, departing Thu, May 29 from Panama City to Porto, returning Wed, Jun 18, priced at $1,096 found 2 days ago
Air France
Fri, Jun 6 - Fri, Jun 13
PTY
Panama City
OPO
Porto
$1,142 Roundtrip, found 13 hours ago
$1,142
Roundtrip
found 13 hours ago
Select Air France flight, departing Fri, Jun 6 from Panama City to Porto, returning Fri, Jun 13, priced at $1,142 found 13 hours ago
Flights from Panama City (PTY) to Porto (OPO)
Origin airport
Tocumen Intl.
Destination airport
Dr. Francisco de Sa Carneiro
Airlines serving
Aeromexico, Air Europa, Air France, American Airlines, Iberia, KLM, Turkish Airlines, United
Roundtrip price
$755
Distance
4806 mi

Panama City to Porto Flights

The cheapest times to fly from Panama City to Porto

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Porto are during the month of May. You can find some of the cheapest flights from Panama City to Porto with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Panama City to Porto

Sunday is one of the best days to book for cheap flights from Panama City to Porto: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Panama City to Porto

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Porto in 2025. You can also book with separate airlines for your outbound and return journeys, from $540 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Porto flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Porto airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Dr. Francisco de Sa Carneiro Airport (OPO) cost?
Discover the latest flight deals from PTY to OPO by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from PTY to OPO?
The cheapest flights from PTY to OPO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PTY to OPO?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from PTY to OPO. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Tocumen Intl. Airport (PTY) to Dr. Francisco de Sa Carneiro Airport (OPO)?
There aren’t any daily direct flights from Tocumen Intl. Airport (PTY) to Dr. Francisco de Sa Carneiro Airport (OPO). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you’ll be cruising above the clouds in no time.
What day of the week has the most flights from PTY to OPO?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on various factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Dr. Francisco de Sa Carneiro Airport (OPO)?
To avoid possible delays on the Tocumen Intl. Airport (PTY) to Dr. Francisco de Sa Carneiro Airport (OPO) route, aim to travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Dr. Francisco de Sa Carneiro Airport (OPO) last-minute?
Booking your ticket from PTY to OPO shortly before your journey is typically more expensive. But if there’s some wiggle room with your itinerary, you could bag a cheap last-minute fare.
Is it cheaper to book a PTY to OPO flight and hotel package?
You’ll typically save money by booking a PTY to OPO flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it’s easy to manage everything in one place. Once you’ve chosen your preferred flights and accommodations, consider other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Dr. Francisco de Sa Carneiro Airport (OPO)?
If you reserved your PTY to OPO flight in the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Explore a world of travel with Expedia

*Available to One Key members.