$182 Cheap Flights from Panama City (PTY) to Manaus (MAO)

View $182 flight on Sat, Jul 5, 2025Opens in a new window

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Cheap Flights from Panama City to Manaus (PTY-MAO)

Prices were available within the past 7 days and start at $182 for one-way flights and $327 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Fri, Jun 6 - Sat, Jun 14
PTY
Panama City
MAO
Manaus
$327 Roundtrip, found 2 days ago
$327
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, Jun 6 from Panama City to Manaus, returning Sat, Jun 14, priced at $327 found 2 days ago
Copa
Fri, Jun 6 - Sat, Jun 14
PTY
Panama City
MAO
Manaus
$336 Roundtrip, found 2 days ago
$336
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Jun 6 from Panama City to Manaus, returning Sat, Jun 14, priced at $336 found 2 days ago
Copa
Tue, May 6 - Wed, May 7
PTY
Panama City
MAO
Manaus
$336 Roundtrip, found 1 day ago
$336
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, May 6 from Panama City to Manaus, returning Wed, May 7, priced at $336 found 1 day ago
avianca
Fri, Jun 6 - Sat, Jun 14
PTY
Panama City
MAO
Manaus
$434 Roundtrip, found 2 days ago
$434
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, Jun 6 from Panama City to Manaus, returning Sat, Jun 14, priced at $434 found 2 days ago
avianca
Tue, Apr 29 - Thu, May 1
PTY
Panama City
MAO
Manaus
$437 Roundtrip, found 5 days ago
$437
Roundtrip
found 5 days ago
Select avianca flight, departing Tue, Apr 29 from Panama City to Manaus, returning Thu, May 1, priced at $437 found 5 days ago
Copa
Tue, Jun 3 - Wed, Jun 11
PTY
Panama City
MAO
Manaus
$441 Roundtrip, found 2 days ago
$441
Roundtrip
found 2 days ago
Select Copa flight, departing Tue, Jun 3 from Panama City to Manaus, returning Wed, Jun 11, priced at $441 found 2 days ago
Copa
Fri, Jun 6 - Sat, Jun 14
PTY
Panama City
MAO
Manaus
$475 Roundtrip, found 2 days ago
$475
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Jun 6 from Panama City to Manaus, returning Sat, Jun 14, priced at $475 found 2 days ago
Copa
Tue, May 6 - Wed, May 7
PTY
Panama City
MAO
Manaus
$475 Roundtrip, found 1 day ago
$475
Roundtrip
found 1 day ago
Select Copa flight, departing Tue, May 6 from Panama City to Manaus, returning Wed, May 7, priced at $475 found 1 day ago
avianca
Fri, May 9 - Thu, May 15
PTY
Panama City
MAO
Manaus
$515 Roundtrip, found 2 days ago
$515
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, May 9 from Panama City to Manaus, returning Thu, May 15, priced at $515 found 2 days ago
avianca
Fri, Jun 6 - Sat, Jun 14
PTY
Panama City
MAO
Manaus
$541 Roundtrip, found 2 days ago
$541
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, Jun 6 from Panama City to Manaus, returning Sat, Jun 14, priced at $541 found 2 days ago
Flights from Panama City (PTY) to Manaus (MAO)
Origin airport
Tocumen Intl.
Destination airport
Eduardo Gomes Intl.
Roundtrip price
$327
Distance
1572 mi

Panama City to Manaus Flights

The cheapest times to fly from Panama City to Manaus

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Manaus are during the month of June. You can find some of the cheapest flights from Panama City to Manaus with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Panama City to Manaus

Sunday is one of the best days to book for cheap flights from Panama City to Manaus: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Panama City to Manaus

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Manaus in 2025. You can also book with separate airlines for your outbound and return journeys, from $182 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Manaus flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Manaus airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How long does it take to fly from Tocumen Intl. Airport (PTY) to Manaus Intl. Airport -- Eduardo Gomes?
Purchase a ticket with Copa Airlines and you can expect to be cruising the skies for roughly 3 hours and 52 minutes. This top carrier has a direct flight that departs at 9:35PM from Panama Airport and arrives at Manaus Intl. Airport – Eduardo Gomes at 2:27AM. Expedia has flight deals to get you soaring, so take a peek at what’s on offer on this route today.
Is it cheaper to buy a plane ticket from Panama Airport to Manaus Intl. Airport -- Eduardo Gomes last minute?
Being a spontaneous soul is a great way to travel around, but it isn’t necessarily the ideal way to find a bargain fare. Think about booking your Panama Airport to Eduardo Gomes Intl. Airport (MAO) journey ahead of time rather than leaving it until the last minute. Based on flight pricing and demand studies in 2022, we have found that the best time to book domestic flights is between 28 – 35 days ahead of the departure date, and international flights three to four months in advance. Leave your spontaneity for when you arrive at your destination!
What airline has the least delays from Tocumen Intl. Airport (PTY) to Manaus Intl. Airport -- Eduardo Gomes?
With an on-time performance rate of 97%, Copa Airlines is the carrier that’s more likely to fly you from PTY to Manaus Intl. Airport – Eduardo Gomes without any hiccups. Flight delays can be an excuse to linger longer at the airport bar. However, they can also lead to a missed connection that upends your vacation. You can prepare for delays by looking up your flight status through the free Expedia App before you even get to the airport. If you’re already there and the delay will significantly impact your plans, head to the customer service desk to discover what your options are.
What airports do you fly into for Manaus from Panama City?
Panama City to Manaus flights arrive at Eduardo Gomes Intl. Airport (MAO). Drop your bags at your hotel and then visit some of the city’s leading attractions, such as Teatro Amazonas and Amazon Arena. The airport is roughly 7 mi north of the center of Manaus.
What are the most popular departure times for flights from PTY to Eduardo Gomes Intl. Airport (MAO)?
Between 9:00 PM - 10:00 PM is the busiest period for Copa Airlines flights going from Tocumen Intl. Airport (PTY) to Eduardo Gomes Intl. Airport (MAO). Our top tip? Fly out earlier in the day. With air traffic yet to build up, your chances of jumping on a delay-free flight are higher.
Can I change the date of my flight from Panama Airport to Manaus Intl. Airport -- Eduardo Gomes?
Sometimes life gets in the way of plans, so Expedia is here to help make amending your trip as easy as possible. To start, find your Panama Airport to MAO itinerary through the Expedia Trips portal and browse the fare rules about what changes can be made. If you purchased your fare in the last 24 hours, some carriers will allow you to cancel for free and book new flights. If you bought your fare more than 24 hours ago, connect with us through our Customer Service portal so we can assist you further.

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*Available to One Key members.