$290 Cheap Flights from Panama City (PTY) to São Paulo (GRU)

View $290 flight on Thu, Jul 24, 2025Opens in a new window
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Cheap Flights from Panama City to São Paulo (PTY-GRU)

Prices were available within the past 7 days and start at $290 for one-way flights and $460 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Mon, May 26 - Thu, May 29
PTY
Panama City
GRU
Sao Paulo
$460 Roundtrip, found 4 hours ago
$460
Roundtrip
found 4 hours ago
Select Copa flight, departing Mon, May 26 from Panama City to Sao Paulo, returning Thu, May 29, priced at $460 found 4 hours ago
Copa
Mon, Jun 9 - Sat, Jun 14
PTY
Panama City
GRU
Sao Paulo
$480 Roundtrip, found 5 days ago
$480
Roundtrip
found 5 days ago
Select Copa flight, departing Mon, Jun 9 from Panama City to Sao Paulo, returning Sat, Jun 14, priced at $480 found 5 days ago
Copa
Mon, May 26 - Thu, May 29
PTY
Panama City
GRU
Sao Paulo
$487 Roundtrip, found 4 hours ago
$487
Roundtrip
found 4 hours ago
Select Copa flight, departing Mon, May 26 from Panama City to Sao Paulo, returning Thu, May 29, priced at $487 found 4 hours ago
Copa
Mon, May 12 - Sat, May 17
PTY
Panama City
GRU
Sao Paulo
$512 Roundtrip, found 21 hours ago
$512
Roundtrip
found 21 hours ago
Select Copa flight, departing Mon, May 12 from Panama City to Sao Paulo, returning Sat, May 17, priced at $512 found 21 hours ago
Copa
Tue, May 20 - Tue, May 27
PTY
Panama City
GRU
Sao Paulo
$512 Roundtrip, found 7 hours ago
$512
Roundtrip
found 7 hours ago
Select Copa flight, departing Tue, May 20 from Panama City to Sao Paulo, returning Tue, May 27, priced at $512 found 7 hours ago
avianca
Fri, May 2 - Sat, May 10
PTY
Panama City
GRU
Sao Paulo
$527 Roundtrip, found 2 days ago
$527
Roundtrip
found 2 days ago
Select avianca flight, departing Fri, May 2 from Panama City to Sao Paulo, returning Sat, May 10, priced at $527 found 2 days ago
Copa
Fri, May 30 - Fri, Jun 6
PTY
Panama City
GRU
Sao Paulo
$539 Roundtrip, found 2 days ago
$539
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, May 30 from Panama City to Sao Paulo, returning Fri, Jun 6, priced at $539 found 2 days ago
Copa
Fri, Jun 20 - Tue, Jun 24
PTY
Panama City
GRU
Sao Paulo
$542 Roundtrip, found 1 hour ago
$542
Roundtrip
found 1 hour ago
Select Copa flight, departing Fri, Jun 20 from Panama City to Sao Paulo, returning Tue, Jun 24, priced at $542 found 1 hour ago
Copa
Thu, Jun 19 - Thu, Jun 26
PTY
Panama City
GRU
Sao Paulo
$555 Roundtrip, found 1 day ago
$555
Roundtrip
found 1 day ago
Select Copa flight, departing Thu, Jun 19 from Panama City to Sao Paulo, returning Thu, Jun 26, priced at $555 found 1 day ago
American Airlines
Sat, Oct 11 - Thu, Oct 23
PTY
Panama City
GRU
Sao Paulo
$1,527 Roundtrip, found 1 day ago
$1,527
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Oct 11 from Panama City to Sao Paulo, returning Thu, Oct 23, priced at $1,527 found 1 day ago

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) cost?
Cheap round-trip flights from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) start from $542. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving PTY on May 14 2025 and touching down at GRU. The price was last updated on April 23 2025 and has not changed since.
What is the cheapest month to fly from PTY to GRU?
The cheapest flights from PTY to GRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Jump on a nonstop flight with Copa Airlines and go straight from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU).
What is the cheapest airline that flies from PTY to GRU?
Jet off from PTY to GRU with Copa. This carrier currently has the lowest one-way fare for this route, starting at $788. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PTY on May 11 2025. Prices were last updated on April 23 2025 and have not changed since.
How many flights per day from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
When flying out of Tocumen Intl. Airport (PTY), you can take your pick from an average of 5 daily nonstop flights to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU).
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
The 3 PM departures from PTY to GRU are the top choice for many travelers. These flights can come with a higher price due to their popularity. If you’re looking to save, book during off-peak hours.
What day of the week has the most flights from PTY to GRU?
If you depart on a Friday, you’ll get the biggest range of choices for flights from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU).
What is the earliest flight from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
Catch the earliest flight at around 12:04PM UTC-5, leaving from Tocumen Intl. Airport (PTY). You’ll be traveling for roughly 6h 46m, coming in to land at Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) at approximately 8:50PM UTC-3.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
It usually takes 6 hours and 42 minutes to fly the 3,200 mi from PTY to GRU.
What airline has the least delays from PTY to GRU?
American Airlines has the strongest track record for on-time direct flights from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU), with an on-time rating of 100%. Use the Expedia App to look up your flight status before you head off and get real-time alerts about any changes.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
To avoid potential delays on the Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) route, fly before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Sao Paulo from Tocumen Intl. Airport (PTY)?
Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) is the only airport in Sao Paulo with direct flights from Tocumen Intl. Airport (PTY). Compare your options and discover affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) last-minute?
Waiting until right before your break to book a flight from PTY to GRU often results in higher prices. While you may find some last-minute discounts, they aren’t always guaranteed. Allow some flexibility in your schedule for a better chance of getting a bargain.
Is it cheaper to book a PTY to GRU flight and hotel package?
You can save money by securing a PTY to GRU flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage it all in one place. After selecting your ideal accommodations and flights, you can add extras like activities, tours and car rentals.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU)?
It’s usually possible to reschedule or cancel your PTY to GRU flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are allowed and whether any costs are involved. You’ll also find further details on our Customer Service portal.
*Available to One Key members.