$353 Cheap Flights from Panama City (PTY) to Buenos Aires (EZE)

Popular airlines from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)

Cheap Flights from Panama City to Buenos Aires (PTY-EZE)

Prices were available within the past 7 days and start at $353 for one-way flights and $604 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Copa
Copa
Copa
Copa
Copa
avianca
Emirates
Aeromexico
American Airlines

Find the cheapest month to fly from Panama City (PTY) to Buenos Aires (EZE)

November is typically the cheapest month to fly

From $533 - $792 per traveler.

Graph displaying average flight prices per month

Flights from Panama City (PTY) to Buenos Aires (EZE)
Origin airport
Tocumen Intl.
Destination airport
Ministro Pistarini Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, Emirates, United, avianca
Roundtrip price
$604
Distance
3323 mi
Average flight time
9 hours 12 mins

Panama City to Buenos Aires Flights

The cheapest times to fly from Panama City to Buenos Aires

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Buenos Aires are during the month of September. You can find some of the cheapest flights from Panama City to Buenos Aires with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Buenos Aires

Sunday is one of the best days to book for cheap flights from Panama City to Buenos Aires: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Buenos Aires

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Buenos Aires in 2025. You can also book with separate airlines for your outbound and return journeys, from $353 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Buenos Aires flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Buenos Aires airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE) cost?
Cheap return fares from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE) start from $604. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving PTY on July 23 2025 and touching down at EZE. The price was last updated on July 12 2025 and has not changed since.
What is the cheapest month to fly from PTY to EZE?
The cheapest flights from PTY to EZE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)?
Fly directly from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE) on a Copa Airlines flight.
What is the cheapest airline that flies from PTY to EZE?
Currently, the cheapest airline offering one-way flights from PTY to EZE is Copa. You can book a seat on this route from $553. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PTY on September 26 2025. Prices were last updated on July 12 2025 and have not changed since.
How many flights per day from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)?
With, on average, 5 direct flights that operate from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE) daily, you'll be off on your next adventure in no time.
What are the most popular departure times for flights from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)?
More passengers fly between PTY and EZE at 3 PM than at any other time of day. Looking for a quieter experience? Travel outside of rush hours and you're likely to save on your ticket as well.
What day of the week has the most flights from PTY to EZE?
Depart on a Friday if you're searching for the best selection of flights from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE).
What is the earliest flight from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)?
The earliest flight departing from Tocumen Intl. Airport (PTY) is at around 12:58PM UTC-5. Catch this flight and you'll reach Ministro Pistarini Intl. Airport (EZE) at approximately 10:13PM UTC-3. The entire trip takes 7h 15m.
How long does it take to fly from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)?
Flights from PTY to EZE have an average travel time of 7 hours and 17 minutes. The distance between these two airports is 3,300 mi.
What airline has the least delays from PTY to EZE?
Copa Airlines has the best performance for on-time direct flights from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE), with an on-time rating of 88%. Use the Expedia App to see your flight schedule before you go and get immediate updates about any trip changes.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)?
To touch down at Ministro Pistarini Intl. Airport (EZE) on time, pick a flight that takes off from Tocumen Intl. Airport (PTY) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Buenos Aires from Tocumen Intl. Airport (PTY)?
If you're flying on a direct flight from Tocumen Intl. Airport (PTY) to Buenos Aires, Ministro Pistarini Intl. Airport (EZE) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE) last-minute?
Holding off until just before your trip to book a flight from PTY to EZE generally means paying more. While you might find some last-minute discounts, there's no guarantee. Allow some flexibility in your schedule for the best chance of snagging a bargain.
Is it cheaper to book a PTY to EZE flight and hotel package?
Booking a PTY to EZE flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip in one place. Choose from our impressive range of stays and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Ministro Pistarini Intl. Airport (EZE)?
In most instances, you can cancel or modify your PTY to EZE flight. However, there may be additional fees, especially if you made your booking more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you want more details, go to our Customer Service portal.

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*Available to One Key members.