$115 Cheap Flights from McAllen (MFE) to San Francisco (SFO)

View $115 flight on Sat, May 31, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from McAllen to San Francisco (MFE-SFO)

Prices were available within the past 7 days and start at $115 for one-way flights and $218 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, May 20 - Fri, May 30
MFE
McAllen
SFO
San Francisco
$218 Roundtrip, found 4 hours ago
$218
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, May 20 from McAllen to San Francisco, returning Fri, May 30, priced at $218 found 4 hours ago
United
Wed, May 21 - Fri, May 30
MFE
McAllen
SFO
San Francisco
$221 Roundtrip, found 4 hours ago
$221
Roundtrip
found 4 hours ago
Select United flight, departing Wed, May 21 from McAllen to San Francisco, returning Fri, May 30, priced at $221 found 4 hours ago
Delta
Wed, May 21 - Fri, May 30
MFE
McAllen
SFO
San Francisco
$226 Roundtrip, found 4 hours ago
$226
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, May 21 from McAllen to San Francisco, returning Fri, May 30, priced at $226 found 4 hours ago
Delta
Mon, May 19 - Sat, May 24
MFE
McAllen
SFO
San Francisco
$231 Roundtrip, found 3 days ago
$231
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, May 19 from McAllen to San Francisco, returning Sat, May 24, priced at $231 found 3 days ago
Delta
Sat, Nov 1 - Mon, Nov 17
MFE
McAllen
SFO
San Francisco
$237 Roundtrip, just found
$237
Roundtrip
just found
Select Delta flight, departing Sat, Nov 1 from McAllen to San Francisco, returning Mon, Nov 17, priced at $237 just found
United
Wed, May 21 - Sat, May 31
MFE
McAllen
SFO
San Francisco
$237 Roundtrip, found 4 hours ago
$237
Roundtrip
found 4 hours ago
Select United flight, departing Wed, May 21 from McAllen to San Francisco, returning Sat, May 31, priced at $237 found 4 hours ago
American Airlines
Wed, May 21 - Fri, May 30
MFE
McAllen
SFO
San Francisco
$238 Roundtrip, found 4 hours ago
$238
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, May 21 from McAllen to San Francisco, returning Fri, May 30, priced at $238 found 4 hours ago
American Airlines
Thu, Sep 18 - Mon, Sep 22
MFE
McAllen
SFO
San Francisco
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Sep 18 from McAllen to San Francisco, returning Mon, Sep 22, priced at $239 found 1 day ago
United
Wed, May 21 - Sun, Jun 1
MFE
McAllen
SFO
San Francisco
$240 Roundtrip, found 4 hours ago
$240
Roundtrip
found 4 hours ago
Select United flight, departing Wed, May 21 from McAllen to San Francisco, returning Sun, Jun 1, priced at $240 found 4 hours ago
Delta
Wed, May 28 - Sat, May 31
MFE
McAllen
SFO
San Francisco
$241 Roundtrip, found 6 days ago
$241
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, May 28 from McAllen to San Francisco, returning Sat, May 31, priced at $241 found 6 days ago

Frequently asked questions

How much does a flight from Miller Intl. Airport (MFE) to San Francisco Intl. Airport (SFO) cost?
Discover the latest flight deals from MFE to SFO by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from MFE to SFO?
The cheapest flights from MFE to SFO are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MFE to SFO?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from MFE to SFO. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Miller Intl. Airport (MFE) to San Francisco Intl. Airport (SFO)?
You’ll have to catch a flight with a layover when traveling from Miller Intl. Airport (MFE) to San Francisco Intl. Airport (SFO). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from MFE to SFO?
Generally you’ll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can change based on the season, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Miller Intl. Airport (MFE) to San Francisco Intl. Airport (SFO)?
To avoid potential delays on the Miller Intl. Airport (MFE) to San Francisco Intl. Airport (SFO) route, fly before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Miller Intl. Airport (MFE) to San Francisco Intl. Airport (SFO) last-minute?
Holding off until just before your departure to book a flight from MFE to SFO generally means paying more. While you may find some last-minute deals, there’s no guarantee. Keep your travel schedule open to maximize your chances of snagging a bargain.
Is it cheaper to book a MFE to SFO flight and hotel package?
You’ll typically save money by securing a MFE to SFO flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s simple to manage everything in one place. After choosing your preferred flights and accommodations, consider other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Miller Intl. Airport (MFE) to San Francisco Intl. Airport (SFO)?
If you booked your MFE to SFO flight within the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for further details.
*Available to One Key members.