$141 Cheap Flights from Mexico City (MEX) to Medellín (MDE)

View $141 flight on Thu, Jun 5, 2025Opens in a new window

Popular airlines from Benito Juarez International Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)

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Find available prices by choosing your travel dates.

Cheap Flights from Mexico City to Medellín (MEX-MDE)

Prices were available within the past 7 days and start at $141 for one-way flights and $279 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Arajet
Mon, Jun 2 - Thu, Jun 5
NLU
Mexico City
MDE
Medellin
$279 Roundtrip, found 2 days ago
$279
Roundtrip
found 2 days ago
Select Arajet flight, departing Mon, Jun 2 from Mexico City to Medellin, returning Thu, Jun 5, priced at $279 found 2 days ago
Arajet
Fri, May 30 - Wed, Jun 4
NLU
Mexico City
MDE
Medellin
$286 Roundtrip, found 23 hours ago
$286
Roundtrip
found 23 hours ago
Select Arajet flight, departing Fri, May 30 from Mexico City to Medellin, returning Wed, Jun 4, priced at $286 found 23 hours ago
Arajet
Thu, Jun 5 - Thu, Jun 12
NLU
Mexico City
MDE
Medellin
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select Arajet flight, departing Thu, Jun 5 from Mexico City to Medellin, returning Thu, Jun 12, priced at $287 found 1 day ago
Copa
Wed, May 14 - Wed, May 21
MEX
Mexico City
MDE
Medellin
$292 Roundtrip, found 5 hours ago
$292
Roundtrip
found 5 hours ago
Select Copa flight, departing Wed, May 14 from Mexico City to Medellin, returning Wed, May 21, priced at $292 found 5 hours ago
Arajet
Fri, May 30 - Wed, Jun 4
NLU
Mexico City
MDE
Medellin
$299 Roundtrip, found 23 hours ago
$299
Roundtrip
found 23 hours ago
Select Arajet flight, departing Fri, May 30 from Mexico City to Medellin, returning Wed, Jun 4, priced at $299 found 23 hours ago
Copa
Wed, May 14 - Wed, May 21
MEX
Mexico City
MDE
Medellin
$302 Roundtrip, found 5 hours ago
$302
Roundtrip
found 5 hours ago
Select Copa flight, departing Wed, May 14 from Mexico City to Medellin, returning Wed, May 21, priced at $302 found 5 hours ago
Arajet
Wed, May 28 - Thu, Jun 12
NLU
Mexico City
MDE
Medellin
$305 Roundtrip, found 1 day ago
$305
Roundtrip
found 1 day ago
Select Arajet flight, departing Wed, May 28 from Mexico City to Medellin, returning Thu, Jun 12, priced at $305 found 1 day ago
avianca
Thu, May 8 - Wed, May 14
MEX
Mexico City
MDE
Medellin
$308 Roundtrip, just found
$308
Roundtrip
just found
Select avianca flight, departing Thu, May 8 from Mexico City to Medellin, returning Wed, May 14, priced at $308 just found
Aeromexico
Sat, May 17 - Fri, Jun 6
MEX
Mexico City
MDE
Medellin
$314 Roundtrip, found 3 hours ago
$314
Roundtrip
found 3 hours ago
Select Aeromexico flight, departing Sat, May 17 from Mexico City to Medellin, returning Fri, Jun 6, priced at $314 found 3 hours ago
Euroairlines
Fri, Jun 6 - Wed, Jul 30
NLU
Mexico City
MDE
Medellin
$631 Roundtrip, found 7 hours ago
$631
Roundtrip
found 7 hours ago
Select Euroairlines flight, departing Fri, Jun 6 from Mexico City to Medellin, returning Wed, Jul 30, priced at $631 found 7 hours ago
Flights from Santa Lucía (NLU) to Medellín (MDE)
Origin airport
Felipe Ángeles Intl.
Destination airport
José María Córdova Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, LATAM Airlines Group, United, avianca
Roundtrip price
$279
Distance
1840 mi

Mexico City to Medellín Flights

The cheapest times to fly from Mexico City to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mexico City to Medellín are during the month of June. You can find some of the cheapest flights from Mexico City to Medellín with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Mexico City to Medellín

Sunday is one of the best days to book for cheap flights from Mexico City to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Mexico City to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mexico City to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $141 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mexico City to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mexico City to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE) cost?
Cheap round-trip flights from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE) start from $296. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Aeromexico flight leaving MEX on May 10 2025 and touching down at MDE. The price was last updated on April 23 2025 and has not changed since.
What is the cheapest month to fly from MEX to MDE?
The cheapest flights from MEX to MDE are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)?
When jetting out of Mexico City Intl. Airport (MEX), you can board a nonstop flight to Jose Maria Cordova Intl. Airport (MDE) with Aeromexico.
What is the cheapest airline that flies from MEX to MDE?
Currently, the cheapest airline operating one-way flights from MEX to MDE is Avianca. You can jet off on this route from $154. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MEX on June 30 2025. Prices were last updated on April 23 2025 and have not changed since.
How many flights per day from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)?
Every day, an average of 2 direct flights operate from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE). Choose the departure date that fits your schedule best.
What are the most popular departure times for flights from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)?
The 5 AM departures from MEX to MDE are typically the busiest. Prices can be higher for these popular slots. If you want to save on your trip, pick a less crowded time to fly.
What day of the week has the most flights from MEX to MDE?
Friday offers the most flights from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE). Consider traveling on this day and you’ll have a greater chance of finding a departure that fits your plans.
What is the earliest flight from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)?
Mexico City Intl. Airport (MEX)’s first flight to Jose Maria Cordova Intl. Airport (MDE) is at approximately 5:00AM UTC-6. With a total journey time of 4h 5m, you’ll touch down at around 10:05AM UTC-5.
How long does it take to fly from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)?
Flights from MEX to MDE have an average travel time of 4 hours and 12 minutes. The distance between the two airports is 1,850 mi.
What airline has the least delays from MEX to MDE?
With 88% of journeys usually arriving as scheduled, AVIANCA has the best on-time performance for direct flights from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE). To keep track of your flight status and get notifications if anything changes, simply head to the Expedia App.
What is the best time to fly from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)?
Book a flight from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE) that takes off before 3 PM to reduce the risk of cancellations and delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Medellin from Mexico City Intl. Airport (MEX)?
Jose Maria Cordova Intl. Airport (MDE) is the only airport in Medellin with direct flights from Mexico City Intl. Airport (MEX). Check out the options and find cheap fares on Expedia.
Is it cheaper to buy a plane ticket from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Booking your flight from MEX to MDE just before your getaway is typically more expensive. However, if you’re flexible with your itinerary, you could score a cheap last-minute fare.
Is it cheaper to book a MEX to MDE flight and hotel package?
Compared with arranging flights and hotels separately, booking a MEX to MDE flight and hotel package with Expedia could result in significant savings. Better still, managing everything in one place will take the hassle out of travel planning. Simply pick your flights and choose from our wide range of hotels, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Mexico City Intl. Airport (MEX) to Jose Maria Cordova Intl. Airport (MDE)?
Typically, it’s possible to cancel or reschedule your MEX to MDE flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline’s policies in your itinerary to see what changes are allowed and whether any costs are involved. You’ll also find more information on our Customer Service portal.

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*Available to One Key members.