$420 Cheap Flights from Madrid (MAD) to Santiago (SCL)

View $420 flight on Fri, May 9, 2025Opens in a new window

Popular airlines from Adolfo Suarez Madrid-Barajas Airport (MAD) to Santiago Intl. Airport (SCL)

Find available prices by choosing your travel dates.

Cheap Flights from Madrid to Santiago (MAD-SCL)

Prices were available within the past 7 days and start at $420 for one-way flights and $814 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Canada
Sat, Feb 7 - Fri, Feb 20
MAD
Madrid
SCL
Santiago
$814 Roundtrip, found 4 days ago
$814
Roundtrip
found 4 days ago
Select Air Canada flight, departing Sat, Feb 7 from Madrid to Santiago, returning Fri, Feb 20, priced at $814 found 4 days ago
Swiss International Air Lines
Sun, Feb 8 - Sun, Feb 22
MAD
Madrid
SCL
Santiago
$837 Roundtrip, found 6 days ago
$837
Roundtrip
found 6 days ago
Select Swiss International Air Lines flight, departing Sun, Feb 8 from Madrid to Santiago, returning Sun, Feb 22, priced at $837 found 6 days ago
Iberia
Sun, May 18 - Sun, Jun 15
MAD
Madrid
SCL
Santiago
$840 Roundtrip, found 3 days ago
$840
Roundtrip
found 3 days ago
Select Iberia flight, departing Sun, May 18 from Madrid to Santiago, returning Sun, Jun 15, priced at $840 found 3 days ago
Iberia
Mon, May 19 - Wed, Jun 4
MAD
Madrid
SCL
Santiago
$848 Roundtrip, found 2 days ago
$848
Roundtrip
found 2 days ago
Select Iberia flight, departing Mon, May 19 from Madrid to Santiago, returning Wed, Jun 4, priced at $848 found 2 days ago
Iberia
Wed, May 7 - Tue, Jun 10
MAD
Madrid
SCL
Santiago
$854 Roundtrip, found 6 days ago
$854
Roundtrip
found 6 days ago
Select Iberia flight, departing Wed, May 7 from Madrid to Santiago, returning Tue, Jun 10, priced at $854 found 6 days ago
Air Canada
Wed, Nov 5 - Thu, Nov 27
MAD
Madrid
SCL
Santiago
$873 Roundtrip, found 2 hours ago
$873
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Wed, Nov 5 from Madrid to Santiago, returning Thu, Nov 27, priced at $873 found 2 hours ago
Air Canada
Wed, Nov 5 - Mon, Nov 24
MAD
Madrid
SCL
Santiago
$886 Roundtrip, found 2 hours ago
$886
Roundtrip
found 2 hours ago
Select Air Canada flight, departing Wed, Nov 5 from Madrid to Santiago, returning Mon, Nov 24, priced at $886 found 2 hours ago
Iberia
Tue, Jun 3 - Tue, Jun 10
MAD
Madrid
SCL
Santiago
$893 Roundtrip, found 4 days ago
$893
Roundtrip
found 4 days ago
Select Iberia flight, departing Tue, Jun 3 from Madrid to Santiago, returning Tue, Jun 10, priced at $893 found 4 days ago
Air France
Tue, May 27 - Wed, Jun 11
MAD
Madrid
SCL
Santiago
$896 Roundtrip, found 3 days ago
$896
Roundtrip
found 3 days ago
Select Air France flight, departing Tue, May 27 from Madrid to Santiago, returning Wed, Jun 11, priced at $896 found 3 days ago
Delta
Tue, Nov 4 - Sat, Nov 15
MAD
Madrid
SCL
Santiago
$916 Roundtrip, found 2 hours ago
$916
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Nov 4 from Madrid to Santiago, returning Sat, Nov 15, priced at $916 found 2 hours ago
Flights from Madrid (MAD) to Santiago (SCL)
Origin airport
Adolfo Suárez Madrid-Barajas
Destination airport
Arturo Merino Benitez
Airlines serving
Aerolineas Argentinas, Aeromexico, Air Canada, Air France, American Airlines, British Airways, Delta, Iberia, KLM, LATAM Airlines Group, Turkish Airlines, United, avianca
Roundtrip price
$814
Distance
6659 mi

Madrid to Santiago Flights

The cheapest times to fly from Madrid to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Madrid to Santiago are during the month of February. You can find some of the cheapest flights from Madrid to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Madrid to Santiago

Sunday is one of the best days to book for cheap flights from Madrid to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Madrid to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Madrid to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $420 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Madrid to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Madrid to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How long does it take to fly from Madrid--Barajas Airport to Arturo Merino Benitez Airport (SCL)?
Book a trip with LATAM Airlines and you’ll be traveling for about 13 hours and 25 minutes. This sought-after airline operates a direct flight that jets off at 1:25PM from Adolfo Suarez Madrid-Barajas Airport (MAD) and reaches Arturo Merino Benitez Airport (SCL) at 8:50PM. Expedia has some great flight deals, so take a peek at what’s available on this route today.
Is it cheaper to buy a plane ticket from Madrid--Barajas Airport to Nuevo Pudahuel Airport last minute?
When it’s time to book your flights, it pays to be prepared. While it’s possible to score a last-minute deal on a MAD to SCL flight, tickets usually don’t get cheaper as the departure date nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days in advance. For international journeys it’s between three and four months.
What airline has the least delays from Madrid Airport to Nuevo Pudahuel Airport?
With an on-time flight record of 75%, LATAM Airlines is the airline most likely to fly you from MAD to Arturo Merino Benitez Airport (SCL) without any hiccups. Flight delays can be an excuse to linger longer at the airport bar. However, they can also cause you to miss a connection that ruins your entire vacation. Keep updated about any delays by looking up your flight status through the free Expedia App long before you get to the airport. If you’re already at your gate and you’re worried about how the disruption will affect your trip, visit your airline’s customer service desk to find out what your options are.
What airports do you fly into for Santiago from Madrid?
Arturo Merino Benitez Airport (SCL), Valparaiso (VAP-Rodelillo Airfield) and Vina del Mar (KNA) are your options when jetting off from Madrid to Santiago. Around 10 mi west of the center of Santiago, Arturo Merino Benitez Airport (SCL) is the city’s principal gateway. Take into account things like flight arrival and departure times and the distance to your hotel before choosing your airport. Plaza de Armas and Patio Bellavista are two terrific attractions to check out when you reach your destination.
What are the most popular departure times for flights from MAD to Santiago International Airport?
The most popular departure times for journeys from Madrid–Barajas Airport to Arturo Merino Benitez Airport (SCL) are between 11:00 PM - 0:00 AM on Iberia. One handy tip is to jet off in the morning. The earlier you go, the greater your chances of a delay-free flight with less air traffic around.
Can I change the date of my flight from Madrid Airport to Nuevo Pudahuel Airport?
Life can throw a spanner in your plans, so Expedia is here to help make amending your flight as easy as possible. To start, access your Adolfo Suarez Madrid-Barajas Airport (MAD) to Arturo Merino Benitez Airport (SCL) itinerary through the Expedia Trips portal and look up the fare rules and conditions to see if change fees apply. If you booked your plane ticket in the last 24 hours, some airlines will let you cancel at no cost and organize new flights. If you bought your fare more than 24 hours ago, get in touch with us through our Customer Service portal to find out what your options are.

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*Available to One Key members.