$43 Cheap Flights from Lisbon (LIS) to Brussels (BRU)

View $43 flight on Thu, May 22, 2025Opens in a new window
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Cheap Flights from Lisbon to Brussels (LIS-BRU)

Prices were available within the past 7 days and start at $43 for one-way flights and $107 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Ryanair
Thu, May 22 - Fri, May 30
LIS
Lisbon
CRL
Charleroi
$107 Roundtrip, found 6 days ago
$107
Roundtrip
found 6 days ago
Select Ryanair flight, departing Thu, May 22 from Lisbon to Charleroi, returning Fri, May 30, priced at $107 found 6 days ago
Ryanair
Thu, Jun 5 - Tue, Jun 17
LIS
Lisbon
CRL
Charleroi
$108 Roundtrip, found 2 days ago
$108
Roundtrip
found 2 days ago
Select Ryanair flight, departing Thu, Jun 5 from Lisbon to Charleroi, returning Tue, Jun 17, priced at $108 found 2 days ago
Ryanair
Thu, Jun 5 - Tue, Jun 17
LIS
Lisbon
CRL
Charleroi
$111 Roundtrip, found 3 days ago
$111
Roundtrip
found 3 days ago
Select Ryanair flight, departing Thu, Jun 5 from Lisbon to Charleroi, returning Tue, Jun 17, priced at $111 found 3 days ago
Ryanair
Mon, May 26 - Wed, May 28
LIS
Lisbon
CRL
Charleroi
$113 Roundtrip, found 4 days ago
$113
Roundtrip
found 4 days ago
Select Ryanair flight, departing Mon, May 26 from Lisbon to Charleroi, returning Wed, May 28, priced at $113 found 4 days ago
Ryanair
Mon, May 26 - Wed, May 28
LIS
Lisbon
CRL
Charleroi
$114 Roundtrip, found 4 days ago
$114
Roundtrip
found 4 days ago
Select Ryanair flight, departing Mon, May 26 from Lisbon to Charleroi, returning Wed, May 28, priced at $114 found 4 days ago
TAP Portugal
Fri, Dec 5 - Mon, Dec 8
LIS
Lisbon
BRU
Brussels
$147 Roundtrip, found 2 days ago
$147
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Fri, Dec 5 from Lisbon to Brussels, returning Mon, Dec 8, priced at $147 found 2 days ago
Air Europa
Thu, Jun 12 - Tue, Jun 17
LIS
Lisbon
BRU
Brussels
$169 Roundtrip, found 1 day ago
$169
Roundtrip
found 1 day ago
Select Air Europa flight, departing Thu, Jun 12 from Lisbon to Brussels, returning Tue, Jun 17, priced at $169 found 1 day ago
Brussels Airlines
Thu, Oct 9 - Wed, Oct 15
LIS
Lisbon
BRU
Brussels
$182 Roundtrip, found 3 days ago
$182
Roundtrip
found 3 days ago
Select Brussels Airlines flight, departing Thu, Oct 9 from Lisbon to Brussels, returning Wed, Oct 15, priced at $182 found 3 days ago
Vueling Airlines
Thu, Sep 11 - Wed, Sep 17
LIS
Lisbon
BRU
Brussels
$183 Roundtrip, found 1 day ago
$183
Roundtrip
found 1 day ago
Select Vueling Airlines flight, departing Thu, Sep 11 from Lisbon to Brussels, returning Wed, Sep 17, priced at $183 found 1 day ago
Iberia
Wed, Dec 17 - Tue, Jan 6
LIS
Lisbon
BRU
Brussels
$206 Roundtrip, found 4 days ago
$206
Roundtrip
found 4 days ago
Select Iberia flight, departing Wed, Dec 17 from Lisbon to Brussels, returning Tue, Jan 6, priced at $206 found 4 days ago
Flights from Lisbon (LIS) to Charleroi (CRL)
Origin airport
Humberto Delgado
Destination airport
Brussels South Charleroi
Airlines serving
Aer Lingus, Air Europa, Austrian Airlines, British Airways, Brussels Airlines, ITA Airways, Iberia, KLM, LOT-Polish Airlines, Lufthansa, Scandinavian Airlines, Swiss International Air Lines, TAP Portugal, Vueling Airlines
Roundtrip price
$107
Distance
1044 mi

Lisbon to Brussels Flights

The cheapest times to fly from Lisbon to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Lisbon to Brussels are during the month of May. You can find some of the cheapest flights from Lisbon to Brussels with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Lisbon to Brussels

Sunday is one of the best days to book for cheap flights from Lisbon to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Lisbon to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Lisbon to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $43 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Lisbon to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Lisbon to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU) cost?
You can score cheap return tickets from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU) starting from $165. Reserve your seat and get ready for takeoff. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a TAP Portugal flight leaving LIS on May 21 2025 and touching down at BRU. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from LIS to BRU?
The cheapest flights from LIS to BRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU)?
When heading out of Humberto Delgado Airport (LIS), you can take a nonstop flight to Brussels - National Airport (BRU) with TAP Portugal.
What is the cheapest airline that flies from LIS to BRU?
Jet off from LIS to BRU with TAP Portugal. This carrier currently has the lowest one-way fare for this route, starting from $80. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from LIS on June 28 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU)?
With, on average, 4 direct flights departing from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU) every day, you’ll be on your way in no time.
What are the most popular departure times for flights from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU)?
More people fly between LIS and BRU at 1 PM than at any other time of day. Rather go when it’s quieter? Try choosing a quieter departure window and there’s a chance you’ll save on your ticket as well.
What day of the week has the most flights from LIS to BRU?
Sunday has the most flights from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU). Consider taking off on this day and you’ll have a greater chance of finding a departure that works with your plans.
What is the earliest flight from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU)?
The first flight of the day taking off from Humberto Delgado Airport (LIS) is at around 7:10AM UTC+0. Catch this flight and you’ll land at Brussels - National Airport (BRU) at approximately 11:00AM UTC+1. The entire trip takes 2h 50m.
How long does it take to fly from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU)?
It usually takes 2 hours and 47 minutes to travel the 1,050 mi from LIS to BRU.
What is the best time to fly from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU)?
To avoid possible delays on the Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU) route, aim to fly before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Brussels from Humberto Delgado Airport (LIS)?
If you’re traveling on a direct flight from Humberto Delgado Airport (LIS) to Brussels, you’ll land at either Brussels - National Airport (BRU) or Brussels South Charleroi Airport (CRL).
Is it cheaper to buy a plane ticket from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU) last-minute?
Last-minute bookings from LIS to BRU are generally more expensive. For the best prices, start looking for flights well ahead of time. That being said, if your travel plans are flexible, you may score a cheap fare right before your trip.
Is it cheaper to book a LIS to BRU flight and hotel package?
Compared with arranging flights and hotels separately, booking a LIS to BRU flight and hotel package with Expedia could lead to significant savings. Better yet, having it all in one place will take the stress out of planning your trip. Just secure your flights and select from our wide range of hotels, then customize your trip with other add-ons like tours and car rentals.
Can I cancel or change the date of my flight from Humberto Delgado Airport (LIS) to Brussels - National Airport (BRU)?
If you booked your LIS to BRU flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of fare you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

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*Available to One Key members.