$120 Cheap Flights from Guayaquil (GYE) to Panama City (PTY)

View $120 flight on Wed, May 21, 2025Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)

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Find available prices by choosing your travel dates.

Cheap Flights from Guayaquil to Panama City (GYE-PTY)

Prices were available within the past 7 days and start at $120 for one-way flights and $247 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, May 30 - Mon, Aug 25
GYE
Guayaquil
PTY
Panama City
$247 Roundtrip, found 2 hours ago
$247
Roundtrip
found 2 hours ago
Select Copa flight, departing Fri, May 30 from Guayaquil to Panama City, returning Mon, Aug 25, priced at $247 found 2 hours ago
Copa
Wed, Jun 4 - Sat, Jun 21
GYE
Guayaquil
PTY
Panama City
$302 Roundtrip, found 6 hours ago
$302
Roundtrip
found 6 hours ago
Select Copa flight, departing Wed, Jun 4 from Guayaquil to Panama City, returning Sat, Jun 21, priced at $302 found 6 hours ago
Copa
Thu, May 8 - Sun, May 11
GYE
Guayaquil
PTY
Panama City
$303 Roundtrip, found 1 day ago
$303
Roundtrip
found 1 day ago
Select Copa flight, departing Thu, May 8 from Guayaquil to Panama City, returning Sun, May 11, priced at $303 found 1 day ago
avianca
Fri, Aug 8 - Mon, Aug 11
GYE
Guayaquil
PTY
Panama City
$307 Roundtrip, found 5 hours ago
$307
Roundtrip
found 5 hours ago
Select avianca flight, departing Fri, Aug 8 from Guayaquil to Panama City, returning Mon, Aug 11, priced at $307 found 5 hours ago
Copa
Wed, May 21 - Sun, May 25
GYE
Guayaquil
PTY
Panama City
$312 Roundtrip, found 1 hour ago
$312
Roundtrip
found 1 hour ago
Select Copa flight, departing Wed, May 21 from Guayaquil to Panama City, returning Sun, May 25, priced at $312 found 1 hour ago
avianca
Fri, May 30 - Mon, Aug 25
GYE
Guayaquil
PTY
Panama City
$319 Roundtrip, found 2 hours ago
$319
Roundtrip
found 2 hours ago
Select avianca flight, departing Fri, May 30 from Guayaquil to Panama City, returning Mon, Aug 25, priced at $319 found 2 hours ago
Copa
Fri, May 30 - Mon, Aug 25
GYE
Guayaquil
PTY
Panama City
$331 Roundtrip, found 2 hours ago
$331
Roundtrip
found 2 hours ago
Select Copa flight, departing Fri, May 30 from Guayaquil to Panama City, returning Mon, Aug 25, priced at $331 found 2 hours ago
avianca
Mon, Jun 9 - Mon, Jun 16
GYE
Guayaquil
PTY
Panama City
$333 Roundtrip, found 11 hours ago
$333
Roundtrip
found 11 hours ago
Select avianca flight, departing Mon, Jun 9 from Guayaquil to Panama City, returning Mon, Jun 16, priced at $333 found 11 hours ago
avianca
Fri, May 30 - Mon, Aug 25
GYE
Guayaquil
PTY
Panama City
$337 Roundtrip, found 2 hours ago
$337
Roundtrip
found 2 hours ago
Select avianca flight, departing Fri, May 30 from Guayaquil to Panama City, returning Mon, Aug 25, priced at $337 found 2 hours ago
Copa
Fri, May 9 - Tue, May 13
GYE
Guayaquil
PTY
Panama City
$339 Roundtrip, found 2 hours ago
$339
Roundtrip
found 2 hours ago
Select Copa flight, departing Fri, May 9 from Guayaquil to Panama City, returning Tue, May 13, priced at $339 found 2 hours ago
Flights from Guayaquil (GYE) to Panama City (PTY)
Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Tocumen Intl.
Airlines serving
Copa, avianca
Roundtrip price
$246
Distance
775 mi

Guayaquil to Panama City Flights

The cheapest times to fly from Guayaquil to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guayaquil to Panama City are during the month of May. You can find some of the cheapest flights from Guayaquil to Panama City with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Guayaquil to Panama City

Sunday is one of the best days to book for cheap flights from Guayaquil to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Guayaquil to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guayaquil to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $120 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guayaquil to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guayaquil to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY) cost?
Snag cheap return fares starting from $302 from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Copa flight leaving GYE on May 19 2025 and touching down at PTY. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from GYE to PTY?
The cheapest flights from GYE to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)?
You can travel nonstop from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY) on a Copa Airlines flight.
What is the cheapest airline that flies from GYE to PTY?
At the moment, the cheapest carrier operating one-way flights from GYE to PTY is Copa. You can jet off on this route from $148. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from GYE on May 28 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)?
When departing from Jose Joaquin de Olmedo Intl. Airport (GYE), you’ll have your pick from an average of 5 daily direct flights to Tocumen Intl. Airport (PTY).
What are the most popular departure times for flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)?
Flights between GYE and PTY are busiest at 4 AM. For a more relaxed experience and possibly cheaper prices, look for a departure that’s outside typical rush times.
What day of the week has the most flights from GYE to PTY?
Friday has the most flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY). Consider leaving on this day and you’ll have a greater chance of finding a departure that fits your itinerary.
What is the earliest flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)?
Catch the earliest flight at around 4:31AM UTC-5, departing from Jose Joaquin de Olmedo Intl. Airport (GYE). You’ll be traveling for roughly 2h 9m, landing at Tocumen Intl. Airport (PTY) at approximately 6:40AM UTC-5.
How long does it take to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)?
It usually takes 2 hours and 9 minutes to travel the 780 mi from GYE to PTY.
What airline has the least delays from GYE to PTY?
With 96% of flights usually arriving as scheduled, Air France has the best on-time performance for nonstop flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY). To check your flight status and receive notifications about any changes, simply head to the Expedia App.
What is the best time to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)?
To avoid possible delays on the Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY) route, aim to travel before 3 PM. Departures after this time have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Panama City from Jose Joaquin de Olmedo Intl. Airport (GYE)?
Browse your flight options from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY). This is the only Panama City airport you can fly into if you’re taking a direct flight.
Is it cheaper to buy a plane ticket from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY) last-minute?
Holding off until just before your departure to book a flight from GYE to PTY generally means paying more. While you may come across some last-minute discounts, there’s no guarantee. Be flexible with your travel plans to boost your chances of snagging a bargain.
Is it cheaper to book a GYE to PTY flight and hotel package?
Compared with arranging flights and hotels separately, booking a GYE to PTY flight and hotel package with Expedia could result in significant savings. Better yet, managing everything in one place will take the stress out of travel planning. Simply pick your flights and choose from our extensive range of stays, then tailor your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Tocumen Intl. Airport (PTY)?
Usually, it’s possible to reschedule or cancel your GYE to PTY flight. However, if it’s been more than 24 hours since booking, additional charges may apply. Check your airline’s policies in your itinerary to see what changes are possible and whether any costs are involved. You’ll also find more information on our Customer Service portal.

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