$207 Cheap Flights from Cancun (CUN) to Santiago (SCL)

Popular airlines from Cancun Intl. Airport (CUN) to Santiago Intl. Airport (SCL)

Find available prices by choosing your travel dates.

Cheap Flights from Cancun to Santiago (CUN-SCL)

Prices were available within the past 7 days and start at $207 for one-way flights and $400 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Arajet
Arajet
Arajet
Arajet
Arajet
Arajet
SKY AIRLINE
Copa
avianca
Aeromexico
Flights from Cancun (CUN) to Santiago (SCL)
Origin airport
Cancun Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Aerolineas Argentinas, Aeromexico, American Airlines, Arajet, Copa, Delta, Euroairlines, LATAM Airlines Group, SKY AIRLINE, United, World Ticket Ltd, avianca
Roundtrip price
$400
Distance
3907 mi

Cancun to Santiago Flights

The cheapest times to fly from Cancun to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cancun to Santiago are during the month of December. You can find some of the cheapest flights from Cancun to Santiago with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Cancun to Santiago

Sunday is one of the best days to book for cheap flights from Cancun to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Cancun to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cancun to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $207 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cancun to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cancun to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL) cost?
Cheap return fares from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL) start from $806. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a LATAM Airlines Group flight leaving CUN on May 18 2025 and touching down at SCL. The price was last updated on April 24 2025 and has not changed since.
What is the cheapest month to fly from CUN to SCL?
The cheapest flights from CUN to SCL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL)?
Catch a nonstop flight with LATAM Airlines and journey straight from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL).
What is the cheapest airline that flies from CUN to SCL?
Currently, the cheapest airline operating one-way flights from CUN to SCL is LATAM Airlines Group. You can jet off on this route from $399. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from CUN on June 22 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL)?
On average, Cancun Intl. Airport (CUN) offers 1 direct flights to Arturo Merino Benitez Airport (SCL) each week. If you want more options, use Expedia’s filters to look for flights with a layover. Fit in a quick visit to another location or simply break up your trip.
What are the most popular departure times for flights from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL)?
More travelers fly between CUN and SCL at 12 PM than at any other time of day. Rather go when it’s quieter? Travel outside of rush hours and you could save on your ticket as well.
What day of the week has the most flights from CUN to SCL?
Travel on a Sunday if you’re searching for the best selection of flights from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL).
What is the earliest flight from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL)?
Take the earliest flight at around 12:50PM UTC-5, leaving from Cancun Intl. Airport (CUN). You’ll be flying for approximately 7h 50m, coming in to land at Arturo Merino Benitez Airport (SCL) at approximately 10:40PM UTC-3.
How long does it take to fly from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL)?
The average flight time from CUN to SCL is 7 hours and 50 minutes, covering a distance of 3,900 mi.
What airline has the least delays from CUN to SCL?
With 88% of journeys typically landing on schedule, LATAM Airlines has the best on-time performance for nonstop flights from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL). To check your flight status and receive notifications if anything changes, head to the Expedia App.
What is the best time to fly from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL)?
To avoid potential delays on the Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL) route, aim to travel before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Santiago from Cancun Intl. Airport (CUN)?
Arturo Merino Benitez Airport (SCL) is the only airport in Santiago with direct flights from Cancun Intl. Airport (CUN). Consider your options and find affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your ticket from CUN to SCL right before your getaway is generally more expensive. But if you’re flexible with your departure times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a CUN to SCL flight and hotel package?
You can save money by securing a CUN to SCL flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s simple to manage it all in one convenient place. After selecting your ideal flights and accommodations, you can add extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from Cancun Intl. Airport (CUN) to Arturo Merino Benitez Airport (SCL)?
Typically, you’re able to reschedule or cancel your CUN to SCL flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline’s policies and fees on flight changes, or if you’d like more details, head to our Customer Service portal.

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*Available to One Key members.