$145 Cheap Flights from Cancun (CUN) to Panama City (PTY)

View $145 flight on Tue, Nov 4, 2025Opens in a new window

Popular airlines from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)

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Find available prices by choosing your travel dates.

Cheap Flights from Cancun to Panama City (CUN-PTY)

Prices were available within the past 7 days and start at $145 for one-way flights and $313 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sat, Oct 4 - Mon, Oct 13
CUN
Cancun
PTY
Panama City
$313 Roundtrip, found 2 hours ago
$313
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Oct 4 from Cancun to Panama City, returning Mon, Oct 13, priced at $313 found 2 hours ago
Aeromexico
Thu, Aug 28 - Sun, Sep 14
CUN
Cancun
PTY
Panama City
$315 Roundtrip, found 18 hours ago
$315
Roundtrip
found 18 hours ago
Select Aeromexico flight, departing Thu, Aug 28 from Cancun to Panama City, returning Sun, Sep 14, priced at $315 found 18 hours ago
avianca
Mon, May 12 - Fri, May 16
CUN
Cancun
PTY
Panama City
$325 Roundtrip, just found
$325
Roundtrip
just found
Select avianca flight, departing Mon, May 12 from Cancun to Panama City, returning Fri, May 16, priced at $325 just found
Copa
Sat, Oct 4 - Mon, Oct 13
CUN
Cancun
PTY
Panama City
$328 Roundtrip, found 2 hours ago
$328
Roundtrip
found 2 hours ago
Select Copa flight, departing Sat, Oct 4 from Cancun to Panama City, returning Mon, Oct 13, priced at $328 found 2 hours ago
avianca
Sat, Oct 4 - Mon, Oct 13
CUN
Cancun
PTY
Panama City
$340 Roundtrip, found 2 hours ago
$340
Roundtrip
found 2 hours ago
Select avianca flight, departing Sat, Oct 4 from Cancun to Panama City, returning Mon, Oct 13, priced at $340 found 2 hours ago
Aeromexico
Fri, Aug 15 - Sat, Aug 30
CUN
Cancun
PTY
Panama City
$341 Roundtrip, found 20 hours ago
$341
Roundtrip
found 20 hours ago
Select Aeromexico flight, departing Fri, Aug 15 from Cancun to Panama City, returning Sat, Aug 30, priced at $341 found 20 hours ago
Copa
Wed, May 14 - Mon, May 19
CUN
Cancun
PTY
Panama City
$344 Roundtrip, found 1 day ago
$344
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, May 14 from Cancun to Panama City, returning Mon, May 19, priced at $344 found 1 day ago
avianca
Wed, May 14 - Thu, May 15
CUN
Cancun
PTY
Panama City
$350 Roundtrip, found 1 day ago
$350
Roundtrip
found 1 day ago
Select avianca flight, departing Wed, May 14 from Cancun to Panama City, returning Thu, May 15, priced at $350 found 1 day ago
United
Wed, May 14 - Mon, May 19
CUN
Cancun
PTY
Panama City
$691 Roundtrip, found 1 day ago
$691
Roundtrip
found 1 day ago
Select United flight, departing Wed, May 14 from Cancun to Panama City, returning Mon, May 19, priced at $691 found 1 day ago
American Airlines
Fri, Jun 13 - Sat, Jun 14
CUN
Cancun
PTY
Panama City
$743 Roundtrip, found 3 days ago
$743
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jun 13 from Cancun to Panama City, returning Sat, Jun 14, priced at $743 found 3 days ago
Flights from Cancun (CUN) to Panama City (PTY)
Origin airport
Cancun Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, American Airlines, Copa, Delta, United, avianca
Roundtrip price
$312
Distance
965 mi

Cancun to Panama City Flights

The cheapest times to fly from Cancun to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Cancun to Panama City are during the month of October. You can find some of the cheapest flights from Cancun to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Cancun to Panama City

Sunday is one of the best days to book for cheap flights from Cancun to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Cancun to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Cancun to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $145 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Cancun to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Cancun to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY) cost?
Discover the latest flight deals from CUN to PTY by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from CUN to PTY?
The cheapest flights from CUN to PTY are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Board a nonstop flight with Copa Airlines and head straight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY).
What is the cheapest airline that flies from CUN to PTY?
Travel from CUN to PTY with Copa. This airline currently offers the cheapest one-way fare on this route, starting from $705. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from CUN on June 24 2025. Prices were last updated on April 24 2025 and have not changed since.
How many flights per day from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Every day on average, 5 direct flights operate from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY). Select the departure date that best fits your itinerary.
What are the most popular departure times for flights from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
The 11 AM departures from CUN to PTY are typically the busiest. These flights can come with a higher price due to their popularity. If you’re hoping to save money, choose a less crowded time to fly.
What day of the week has the most flights from CUN to PTY?
If you depart on a Friday, you’ll get the greatest range of options for flights from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY).
What is the earliest flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Cancun Intl. Airport (CUN)’s first flight to Tocumen Intl. Airport (PTY) takes off at approximately 7:53AM UTC-5. With a total flight time of 2h 41m, you’ll arrive at around 10:34AM UTC-5.
How long does it take to fly from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
The average flight time from CUN to PTY is 2 hours and 40 minutes, covering a distance of 970 mi.
What airline has the least delays from CUN to PTY?
Aeromexico has the strongest track record for on-time direct flights from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY), with an on-time rating of 97%. Use the Expedia App to view your flight status before you jet off and receive notifications about any changes.
What is the best time to fly from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
Opt for a flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY) that leaves before 3 PM to reduce the risk of delays and cancellations. Later departures are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
What airports do you fly into for Panama City from Cancun Intl. Airport (CUN)?
If you’re flying on a direct flight from Cancun Intl. Airport (CUN) to Panama City, Tocumen Intl. Airport (PTY) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY) last-minute?
Waiting until just before your departure to book your flight from CUN to PTY generally means paying more. While it’s possible to find some last-minute offers, there’s no guarantee. Keep your travel schedule open to boost your chances of landing a bargain.
Is it cheaper to book a CUN to PTY flight and hotel package?
You’ll typically save money by booking a CUN to PTY flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it’s easy to manage it all in one place. After choosing your preferred accommodations and flights, you can add extras such as tours, car rentals and activities.
Can I cancel or change the date of my flight from Cancun Intl. Airport (CUN) to Tocumen Intl. Airport (PTY)?
In most instances, you can cancel or modify your CUN to PTY flight. However, additional charges may apply, especially if you made your booking over 24 hours ago. Double-check your itinerary for the airline’s guidelines and fees on flight changes, or if you need more details, visit our Customer Service portal.

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*Available to One Key members.