$124 Cheap Flights from Knoxville (TYS) to Los Angeles (LAX)

View $124 flight on Sun, May 25, 2025Opens in a new window

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Find available prices by choosing your travel dates.

Cheap Flights from Knoxville to Los Angeles (TYS-LAX)

Prices were available within the past 7 days and start at $124 for one-way flights and $208 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, May 22 - Sun, Jun 1
TYS
Knoxville
LAX
Los Angeles
$208 Roundtrip, found 2 days ago
$208
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, May 22 from Knoxville to Los Angeles, returning Sun, Jun 1, priced at $208 found 2 days ago
Frontier Airlines
Sun, May 25 - Wed, May 28
TYS
Knoxville
LAX
Los Angeles
$238 Roundtrip, found 14 hours ago
$238
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Sun, May 25 from Knoxville to Los Angeles, returning Wed, May 28, priced at $238 found 14 hours ago
Frontier Airlines
Thu, May 29 - Thu, Jun 5
TYS
Knoxville
LAX
Los Angeles
$248 Roundtrip, found 5 hours ago
$248
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Thu, May 29 from Knoxville to Los Angeles, returning Thu, Jun 5, priced at $248 found 5 hours ago
Frontier Airlines
Thu, May 22 - Wed, May 28
TYS
Knoxville
LAX
Los Angeles
$277 Roundtrip, found 14 hours ago
$277
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Thu, May 22 from Knoxville to Los Angeles, returning Wed, May 28, priced at $277 found 14 hours ago
Frontier Airlines
Sun, May 25 - Thu, May 29
TYS
Knoxville
LAX
Los Angeles
$280 Roundtrip, found 2 days ago
$280
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, May 25 from Knoxville to Los Angeles, returning Thu, May 29, priced at $280 found 2 days ago
Frontier Airlines
Thu, May 22 - Tue, May 27
TYS
Knoxville
LAX
Los Angeles
$283 Roundtrip, found 6 days ago
$283
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, May 22 from Knoxville to Los Angeles, returning Tue, May 27, priced at $283 found 6 days ago
Frontier Airlines
Sun, May 25 - Tue, May 27
TYS
Knoxville
LAX
Los Angeles
$294 Roundtrip, found 2 hours ago
$294
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Sun, May 25 from Knoxville to Los Angeles, returning Tue, May 27, priced at $294 found 2 hours ago
American Airlines
Sat, May 24 - Mon, May 26
TYS
Knoxville
LAX
Los Angeles
$340 Roundtrip, found 14 hours ago
$340
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sat, May 24 from Knoxville to Los Angeles, returning Mon, May 26, priced at $340 found 14 hours ago
United
Sat, May 31 - Thu, Jun 5
TYS
Knoxville
LAX
Los Angeles
$367 Roundtrip, found 6 days ago
$367
Roundtrip
found 6 days ago
Select United flight, departing Sat, May 31 from Knoxville to Los Angeles, returning Thu, Jun 5, priced at $367 found 6 days ago
Delta
Wed, May 21 - Sat, May 24
TYS
Knoxville
LAX
Los Angeles
$390 Roundtrip, found 2 days ago
$390
Roundtrip
found 2 days ago
Select Delta flight, departing Wed, May 21 from Knoxville to Los Angeles, returning Sat, May 24, priced at $390 found 2 days ago
Flights from Knoxville (TYS) to Los Angeles (LAX)
Origin airport
McGhee Tyson
Destination airport
Los Angeles Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, United
Roundtrip price
$208
Distance
1944 mi

Knoxville to Los Angeles Flights

The cheapest times to fly from Knoxville to Los Angeles

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Knoxville to Los Angeles are during the month of May. You can find some of the cheapest flights from Knoxville to Los Angeles with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Knoxville to Los Angeles

Sunday is one of the best days to book for cheap flights from Knoxville to Los Angeles: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Knoxville to Los Angeles

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Knoxville to Los Angeles in 2025. You can also book with separate airlines for your outbound and return journeys, from $124 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Knoxville to Los Angeles flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Knoxville to Los Angeles airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently asked questions

How much does a flight from McGhee Tyson Airport (TYS) to Los Angeles Intl. Airport (LAX) cost?
Discover the latest flight deals from TYS to LAX by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from TYS to LAX?
The cheapest flights from TYS to LAX are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from TYS to LAX?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from TYS to LAX. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from McGhee Tyson Airport (TYS) to Los Angeles Intl. Airport (LAX)?
There are no daily direct flights departing from McGhee Tyson Airport (TYS) to Los Angeles Intl. Airport (LAX). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you’ll be soaring above the clouds in no time.
What day of the week has the most flights from TYS to LAX?
You’ll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from McGhee Tyson Airport (TYS) to Los Angeles Intl. Airport (LAX)?
To arrive at Los Angeles Intl. Airport (LAX) on time, pick a flight that takes off from McGhee Tyson Airport (TYS) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from McGhee Tyson Airport (TYS) to Los Angeles Intl. Airport (LAX) last-minute?
Waiting until just before your departure to book a flight from TYS to LAX generally means paying more. While you may come across some last-minute offers, there’s no guarantee. Allow some flexibility in your schedule for the best chance of landing a bargain.
Is it cheaper to book a TYS to LAX flight and hotel package?
Compared with arranging flights and hotels separately, booking a TYS to LAX flight and hotel package with Expedia could result in significant savings. Better still, having everything in one convenient place takes the hassle out of planning your trip. Just secure your flights and choose from our extensive range of hotels, then customize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from McGhee Tyson Airport (TYS) to Los Angeles Intl. Airport (LAX)?
Typically, it’s possible to reschedule or cancel your TYS to LAX flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline’s policies in your itinerary to see what changes are allowed and if any costs are involved. You’ll also find more information on our Customer Service portal.

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*Available to One Key members.