21c Museum Hotel Louisville

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Luxury
4.5 star property
9.4

Exceptional

Art museum meets boutique retreat

Acclaimed restaurant Proof on Main serves phenomenal cuisine in an artsy atmosphere connected to the hotel's museum gallery. Guests can retreat to the full-service spa for rejuvenating massages. The downtown Louisville location puts museums, bourbon tours, and attractions within walking distance.

Popular amenities

  • Spa
  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Gym

Room options

Available filters for rooms
Showing 12 of 12 rooms

View all photos for Deluxe Double Room, 2 Double Beds

A hotel room with two beds, a headboard with a framed artwork of birds, a bedside table with a lamp, and a small bookshelf.

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(34 reviews)
  • 335 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free wired internet

View all photos for Luxury Double Room, 2 Double Beds

A hotel room with two beds, a desk, a chair, a lamp, and a large window with a view.

Luxury Double Room, 2 Double Beds

  • City view
  • 435 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free wired internet

View all photos for Deluxe Room, 1 King Bed

A hotel room with a bed, a desk, a chair, a lamp, a plant, and a TV on the wall.

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(82 reviews)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Luxury Room, 1 King Bed

A hotel room with a large bed, a chair, a desk, and a window with curtains.

Luxury Room, 1 King Bed

9.0 out of 10
Wonderful
(37 reviews)
  • City view
  • 455 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Suite, Corner

A modern living room with a grey sofa, a red decorative piece, a white armchair, and a dining area with a table and chairs.

Suite, Corner

  • City view
  • 660 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Room (Asleep in the Cyclone)

A room with a geometric-patterned ceiling, a bed with a patterned bedspread, and a nightstand with a lamp.

Room (Asleep in the Cyclone)

  • 500 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Suite (Atrium)

A hotel room with a bed, desk, chair, dresser, and a sofa.

Suite (Atrium)

  • 580 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Room, Balcony

A hotel room with a large bed, a nightstand with a lamp, a chair, and a view of the outdoors.

Room, Balcony

10.0 out of 10
Exceptional
(1 review)
  • City view
  • 315 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Deluxe Double Room, Accessible

A modern bathroom with a white sink, mirror, and toilet.

Deluxe Double Room, Accessible

9.0 out of 10
Wonderful
(2 reviews)
  • 455 sq ft
  • Sleeps 4
  • 2 Double Beds
  • Free wired internet

View all photos for Deluxe Room, 1 King Bed, Accessible

A hotel room with a large bed, two bedside tables with lamps, a wooden headboard, a large mirror, and a wall-mounted abstract art piece.

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(2 reviews)
  • 434 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Deluxe Room, 1 King Bed, Accessible

A hotel room with a large bed, two bedside tables with lamps, a wooden headboard, a large mirror, and a wall-mounted abstract art piece.

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 435 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Apartment, 1 Double Bed (Rooftop)

A modern interior with a dining area, a patterned bench, and a large window with a city view.

Apartment, 1 Double Bed (Rooftop)

10.0 out of 10
Exceptional
(1 review)
  • City view
  • Sleeps 4
  • 1 Double Bed
  • Free wired internet

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  • Pet friendly
  • Free WiFi
  • Restaurant
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About this property

21c Museum Hotel Louisville

  • Luxury boutique hotel in the business district
  • A short walk from Kentucky International Convention Center and KFC Yum Center, 21c Museum Hotel Louisville provides dry cleaning/laundry services, a bar, and a 24-hour gym. Treat yourself to a hot stone massage at 21c Spa, the onsite spa. The on-site restaurant, Proof on Main, offers breakfast, brunch, lunch, and dinner. In addition to a 24-hour business center, guests can connect to free in-room WiFi.
  • You'll also enjoy perks such as:
    • Limo/town car service, full breakfast (surcharge), and valet parking (surcharge)
    • An electric car charging station, meeting rooms, and a porter/bellhop
    • A front-desk safe, a gift shop, and smoke-free premises
    • Guest reviews speak highly of the dining options, helpful staff, and location
  • Room features
  • All 91 rooms include comforts such as premium bedding and laptop-compatible safes, in addition to perks like laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the clean rooms at the property.
  • Extra conveniences in all rooms include:
    • Hypo-allergenic bedding, down comforters, and rollaway/extra beds (surcharge)
    • Bathrooms with designer toiletries and hair dryers
    • 50-inch HDTVs with premium channels
    • Wardrobes/closets, free infant beds, and daily housekeeping

Awards and affiliations

  • Sustainability Certifications
  • This property is certified by this third-party sustainability certification scheme: Green Key Global. For more information on what this certification requires and verifies, please visit their website.

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  • Free WiFi
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Policies

Check-in

Check-in start time: 4 PM; Check-in end time: midnight

Contactless check-in available

Minimum check-in age: 21

Check-out

Check-out before 11 AM

Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Information provided by the property may be translated using automated translation tools

Minors may not be accommodated at the property without an accompanying parent or legal guardian. Guests may be required to provide proof of the parental or legal guardian relationship and authorization upon arrival.

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 40.00 per accommodation, per stay

Service animals are welcome, and are exempt from fees

Up to 50 lbs per pet

Food and water bowls are available

Children and extra beds

Children are welcome

Rollaway/extra beds are available for USD 30.0 per night

Free cribs are available on request at the property

Property payment types

  • American Express
  • Discover
  • Mastercard
  • Visa

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5.00 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Is 21c Museum Hotel Louisville pet-friendly?

Yes, this hotel allows pets with a maximum weight of up to 50 lbs per pet. There's a fee of USD 40.00 per accommodation, per stay. Service animals are exempt from fees.

How much does it cost to stay at 21c Museum Hotel Louisville?

As of Nov 4, 2026, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Louisville on Nov 24, 2026 start from $184, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking?

Valet parking is available for USD 32 per night.

What time is check-in at 21c Museum Hotel Louisville?

Check-in start time: 4 PM; Check-in end time: midnight.

What time is check-out at 21c Museum Hotel Louisville?

Check-out is at 11 AM.

Where is 21c Museum Hotel Louisville located?

Located in Downtown Louisville, this luxury hotel is steps from Ohio River Valley and Louisville Slugger Museum. KFC Yum Center and Fourth Street Live! are also within 10 minutes.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

21c Museum Hotel Louisville Reviews

9.4

Exceptional

9.6

Cleanliness

9.0

Amenities

9.4

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 784 out of 1000 reviews
Rating 8 - Good. 117 out of 1000 reviews
Rating 6 - Okay. 61 out of 1000 reviews
Rating 4 - Poor. 19 out of 1000 reviews
Rating 2 - Terrible. 19 out of 1000 reviews

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a great stay! The room and location were perfect, and the staff were very accommodating!
Stayed 4 nights in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Best hotel in downtown Louisville, pricey yes, but everything else screams luxury and if customer service matters to you, you need to stay.
Stayed 1 night in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was our second stay here and will stay again when in town. Very cool place if you like art. Great service. Nice room but nothing really special about it. Super convenient location downtown on Main Street, walking distance to many attractions and distilleries. Very good on-site restaurant/bar.
Stayed 3 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was wonderful. Usually sleep horribly in hotel but slept like a baby. Loved the pillows and mattress.
Stayed 1 night in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Unique and fun place to stay. Loved the art works displayed throughout the property. Appreciated the sense of humor with the red penguins that surprised us appearing at different locations every day. Staff was professional and friendly. Small fridge in the room would have been nice.
Stayed 3 nights in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff!
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It’s beautiful and unique; also well situated….
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
If you love ORIGINALITY this is the place!!! We absolutely loved our stay …. funky, innovative and simply refreshing. The inspiring art is an absolute treat. Great taste and finally not another copycat hotel. AND the service was excellent, bed super comfortable, lovely bathroom and we couldn’t have been happier. If you haven’t tried it. It’s an absolute must!!!
Stayed 1 night in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We love 21C, whenever we travel that is our first go to hotel. We have one in our hometown and love what it offers and the rooms are phenomenal
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful property, on-site restaurant was delicious. Beds very nice.
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Convenient location.
Stayed 2 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Unique hotel with character. There's a museum inside and they provide you with a free bourbon sample to tour it. And the PENGUINS. Everywhere there are 3' tall red plastic penguins that seem to move around the hotel. What a fun idea. Woke up to one in front of our door one morning. Great staff!!! So helpful and great to talk to. Everyone from the doorman to the front desk and bar staff. Also loved the bar! Cici was amazing!
Stayed 5 nights in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel is quite unique with the art displayed throughout and the rooms are very well appointed with comfortable beds
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved this hotel and museum. Really enjoyed leisurely walking the museum with a bourbon in hand!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was nice. Staff was helpful. Restaurant was excellent.
Stayed 2 nights in Jul 2026
Verified review

2/10 Terrible

Liked: Cleanliness, property conditions & facilities
Disliked: Staff & service, amenities
The beds were comfortable on the front desk. Staff was great other than that not a place to host a venue at all.
Stayed 2 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very cool hotel with an art studio within it. Great staff. Great location. Great room and amenities.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Mini fridge in room is full of paid items. No room to store any left overs or drinks. Otherwise everything was very nice. Clean room and rr, water pressure was great, museum was a nice spot to wander around and learn a bit. Easy in and out.
Stayed 1 night in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely experience, room was beautiful, clean, comfortable; staff was welcoming. Hotel was just lovely. We would definitely go back and highly recommend it to other travelers.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stayed there for thunder and it was so pleasant! Quiet and comfortable. All staff was very helpful and the cleanliness of the entire hotel was amazing!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Nice room and close to all the distilleries. Great restaurant on site as well!
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Large spacious room and super comfortable bed Fascinating art and super bar and restaurant too Great service from all staff
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel And staff. Will come. Back
Stayed 2 nights in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Great room, super kind staff
Stayed 2 nights in Feb 2026