491 Properties in Panama City, Panamá Province, Panama. ${startDate} through ${endDate}

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A gym with treadmills, weight machines, and a red carpet.

A buffet with various food items and a decorative plant.

Sheraton Grand Panama

San Francisco

Spa

Rooftop garden

Bar and lounge

Spa, Rooftop garden, Bar and lounge

8.68.6 out of 10

Excellentexcellent

1,001 reviews(1,001 reviews)

$176 nightly

The current price is $386 total

$386 total

Total with taxes and fees

We have 5 left at this price

Mon, Oct 5 - Wed, Oct 7

Mon 5 of October 2026 to Wed 7 of October 2026

More information about Sheraton Grand Panama, opens in a new tab

A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.

A hotel named PRINCIPE with a modern facade and large glass windows.

Principe Hotel and Suites

El Cangrejo

Bar and lounge

International cuisine restaurant

Room service

Bar and lounge, International cuisine restaurant, Room service

Fully refundable

Reserve now, pay later

9.09.0 out of 10

Wonderfulwonderful

2,034 reviews(2,034 reviews)

$45 off

$59 nightly

The current price is $130 total

$130 total

Total with taxes and fees

We have 6 left at this price

Fri, Oct 2 - Sun, Oct 4

Fri 2 of October 2026 to Sun 4 of October 2026

More information about Principe Hotel and Suites, opens in a new tab

A hotel room with two beds, a desk, and a large window offering a city view.

A covered outdoor seating area with a view of a city skyline and water.

VIP Access

Plaza Paitilla Inn Hotel

Punta Paitilla

Spa services

Bar and lounge

International cuisine restaurant

Spa services, Bar and lounge, International cuisine restaurant

Fully refundable

Reserve now, pay later

9.49.4 out of 10

Exceptionalexceptional

2,236 reviews(2,236 reviews)

$146 off

$103 nightly

The current price is $227 total

$227 total

Total with taxes and fees

We have 4 left at this price

Thu, Oct 1 - Sat, Oct 3

Thu 1 of October 2026 to Sat 3 of October 2026

More information about Plaza Paitilla Inn Hotel, opens in a new tab

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Photo gallery for Sheraton Grand Panama

Sheraton Grand Panama

Photo gallery for Principe Hotel and Suites

Principe Hotel and Suites

Photo gallery for Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel