Skip to main content

Stays
Flights
Cars
Packages
Things to do
Cruises

Deals
Groups & meetings
Expedia Magazine
One Key credit cards

Open app
List your property
Support
Trips
Unlock instant savings with Member Prices
- Sign in
- Learn more about One Key
- Feedback

114 Properties in 646 Main St, Buffalo, NY 14202, USA. April 10, 2026 through April 12, 2026

Where to?

Dates

Travelers

Room 1

Adults

ChildrenAges 0 to 17

Need to book 9 or more rooms?

Sort & Filter

Compare properties

Get a side-by-side view of up to 5 properties.

Search by property name

e.g. Marriott

Filter by

Traveler experience

Eco-certifications

LGBTQ welcoming

Business friendly

Family friendly

Adults only

Wedding

Romantic

Budget

Beach

Luxury

Guest rating

Guest rating

Any

Wonderful 9+

Very good 8+

Good 7+

Star rating

2 stars

3 stars

4 stars

1 star

5 stars

Property type

Houseboat

Riad

Condo resort

Farm

Safari

Condo

Cottage

TownHouse

Aparthotel

Tree house

Resort

Capsule Hotel

Ryokan

Inn

Residence

Lodge

Cabin

Palace

Cruise

Hotel

Castle

Hostal

Private vacation home

Villa

Bed & breakfast

Pousada (Brazil)

Country House

Motel

Holiday Park

Pension

Hostel/Backpacker accommodation

Ranch

Pousada

Apartment

Guesthouse

Chalet

Camping

Room amenities

In-room entertainment

Personal safe

Yard

Fireplace

WiFi

Refrigerator

Coffee/tea maker

Private sauna

Swim-up room

Kitchen or kitchenette

Private pool

Ground floor

Balcony or patio

Porch or lanai

Private bathroom

Blackout curtains

Air conditioning

Accessibility features

Top floor

Private hot tub

Jetted or soaking bathtub

Property amenities

Water park

Parking

Outdoor space

Cribs

Golf course

Gym

Restaurant

Airport shuttle included

Hot tub

Wifi Included

Electric car charging station

Kitchen

Washer and dryer

Pet friendly

Bar

Casino

Spa

Air conditioned

Pool

Indoor pool

Payment type

Reserve now, pay at property

Pay over time with Affirm

Room views

Water view

Marina view

Vineyard view

Courtyard view

River view

Beach view

Mountain view

Golf course view

Desert view

Park view

Garden view

Lake view

Harbor view

Ocean view

Lagoon view

Pool view

City view

Canal view

Bay view

Valley view

Resort view

Hill view

One Key benefits and discounts

Discounted properties

Major discounts on selected stays

VIP Access properties

Top-rated stays with member perks

Member Prices

Sign in for instant savings

Accessibility

Roll-in shower

Stair-free path to entrance

Service animals allowed

Sign language-capable staff

In-room accessibility

Accessible bathroom

Elevator

Wheelchair accessible parking

Meal plans available

All inclusive

Breakfast included

Dinner included

Lunch included

Total price

Min

Max

$0, Minimum, Total price

$663, Maximum, Total price

Availability

Only show available properties

Property cancellation options

Fully refundable property

Popular filters

Popular

Near popular events

Near popular events

Rochester Knighthawks vs Buffalo BanditsKeyBank Center Apr 11

Neighborhood

Neighborhood

Buffalo (and vicinity)

Amherst

Downtown Buffalo

Hamburg

Orchard Park

Williamsville

Cheektowaga

Buffalo

West Seneca

Tonawanda

Lackawanna

Clarence

Lancaster

Depew

Kenmore

Blasdell

Bowmansville

Getzville

Buffalo, NY (BUF-Buffalo Niagara Intl.)

Buffalo-Depew Station

Property brand

Holiday Inn

Hampton Inn

Quality

Hilton Garden Inn

Lodgable

Comfort Inn

Holiday Inn Express

Best Western

Residence Inn

Doubletree

Fairfield Inn and Suites

Tribute Portfolio

Wyndham Hotels

eviivo NORAM

Hyatt Place

Courtyard

Candlewood Suites

aloft

Budget Host

Westin

Red Carpet Inn

Microtel Inn

Marriott Hotels & Resorts

Sleep Inn

Home2 Suites by Hilton

InnRoad

La Quinta Inn & Suites

Staybridge Suites

Ascend Collection

Tapestry Collection by Hilton

HomeTowne Studios

Extended Stay America Suites

Super 8

Hyatt Regency

Red Roof Inn

Wingate Inn

Homewood Suites

Embassy Suites

Econo Lodge

SpringHill Suites

Days Inn

BedandBreakfast.com

Baymont Inns & Suites

Spark by Hilton

Motel 6

CAMBRiA hotel & suites

Suburban Extended Stay

Crowne Plaza

voco

Red Roof Plus+

Sheraton Hotel

Trademark

TownePlace Suites

Best Western Plus

Scottish Inn

Voyajoy

Tru by Hilton

SureStay

Country Inn & Suites - by Choice Hotels

Travelodge

All stays

Hotels

Homes

114 properties

How our sort order works

Search results

Lunch and dinner served, American cuisine. Buffalo Airport Hotel

Buffalo Airport Hotel

Cheektowaga

Airport shuttle included

Fully refundable

8.08.0 out of 10

Very Good

very good

2,908 reviews

(2,908 reviews)

$98 nightly

The current price is $223 total

$223 total

Total with taxes and fees

We have 8 left at this price

More information about Buffalo Airport Hotel, opens in a new tab

M Hotel Buffalo

Cheektowaga

Breakfast included
Pool
Airport shuttle included

Fully refundable

Reserve now, pay later

7.47.4 out of 10

Good

good

2,677 reviews

(2,677 reviews)

$199 nightly

The current price is $453 total

$453 total

Total with taxes and fees

We have 3 left at this price

Sign in for extra savings

More information about M Hotel Buffalo, opens in a new tab

Deluxe Room, Non Smoking (2 Double Beds & Sofa Bed) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds. Sleep Inn & Suites Buffalo Airport

Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds. Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

Cheektowaga

Breakfast included
Airport shuttle included

8.08.0 out of 10

Very Good

very good

2,015 reviews

(2,015 reviews)

$101 nightly

The current price is $230 total

$230 total

Total with taxes and fees

Sign in for extra savings

More information about Sleep Inn & Suites Buffalo Airport, opens in a new tab

Loading