Cape Girardeau, MO

Travel Guide

A calm body of water, a sandy beach, and a forested area in the distance.
A large tree in a park with a fountain in the background.
A bridge with illuminated cables at dusk.
A large suspension bridge over a river with a cityscape in the background.
A train track alongside a river, surrounded by autumn foliage and industrial buildings.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
$100 nightly
The price is $113 total per night from Sep 20 to Sep 21
$113 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
$105 nightly
The price is $119 total per night from Sep 15 to Sep 16
$119 total
Sep 15 - Sep 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
9.4/10 Exceptional! (661 reviews)
"I can’t rave enough about this hotel. 5 ♥️s. It takes zero effort to be kind. The staff is kind and helpful. Highly recommend to anyone staying in Cape Girardeau, MO. This hotel rises above the chain hotels 🏨."

Reviewed on Sep 12, 2026

The Riverview
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Sep 20 to Sep 21
$81 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,005 reviews)
"Didn't notice bathroom venting."

Reviewed on Sep 13, 2026

Pear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attractions Show Me Center and Century ...
9.8/10 Exceptional! (31 reviews)
"Property was as described. Had things within the house to keep us entertained, such as fusball . Located near the college and stores."

Reviewed on Sep 7, 2026

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau
Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau MO
Stay at this vacation home in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions eDen Spa & Salon and The Glenn House are ...
Serenity South -- Gardens, River-Views, and Refreshing Space
The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse

Cape Girardeau MO
Stay at this cabin in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions Cape Girardeau Conservation Nature Center and Cape ...
10/10 Exceptional! (36 reviews)
"The hosts were excellent."

Reviewed on Jul 22, 2026

The Twisted Sassafras Treehouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Cape Girardeau attractions

Frequently asked questions

Is Cape Girardeau worth visiting?
Cape Girardeau is worth visiting for its standout attractions like Southeast Missouri State University and Riverfront Bridge Park. Travelers can also enjoy a diverse food scene, with options for North American and Asian cuisine.
When is the best time to visit Cape Girardeau?
The best time to visit Cape Girardeau is from April through June, when the weather is generally pleasant for exploring. For fewer crowds and better value, the months of November through February are a good option, offering cooler temperatures and a more relaxed atmosphere.
What is Cape Girardeau known for?
Cape Girardeau is known for Southeast Missouri State University and its Riverfront Bridge Park. Travelers can also enjoy the Cape Splash Family Aquatic Center. This riverside city on the Mississippi River is named after Jean Baptiste de Girardot and offers a North American food culture.
What is a good itinerary length for Cape Girardeau?
A good itinerary length for Cape Girardeau is one to two days to explore highlights like Southeast Missouri State University, Riverfront Bridge Park, and Cape Splash Family Aquatic Center. For a more relaxed trip, consider three to four days, allowing extra time to enjoy these attractions and sample the local North American, Asian, or Italian cuisine.
What are the top things to do in and around Cape Girardeau?
Cape Girardeau offers a mix of outdoor spaces, family fun, and university exploration for travelers:


How do I plan a trip to Cape Girardeau?
To plan your trip to Cape Girardeau, book hotels, flights, and rental cars in advance. Explore attractions like Southeast Missouri State University, Riverfront Bridge Park, and Cape Splash Family Aquatic Center. For outdoor activities, plan for early morning or late afternoon. Enjoy dining at North American, Asian, or Italian restaurants during your stay.
What cuisines can you find in Cape Girardeau?
In Cape Girardeau, travelers can find Mediterranean cuisine, with dishes like hummus, gyros, and falafel. You'll also discover North American options, Asian fare including Chinese and Japanese, Italian classics such as pasta, and Latin American choices like Mexican tacos and burritos.
Can I book a refundable hotel in Cape Girardeau?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Cape Girardeau by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Cape Girardeau with Expedia?
Expedia makes it easier to plan your Cape Girardeau trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Cape Girardeau?
The best choice depends on your travel style. Hotels in Cape Girardeau can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Cape Girardeau trip on Expedia?
Once you've booked your Cape Girardeau trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Cape Girardeau trip?
Expedia offers customer support before, during, and after your Cape Girardeau trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Cape Girardeau?
If it's your first trip to Cape Girardeau, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Cape Girardeau hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Cape Girardeau hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Cape Girardeau

Explore a world of travel with Expedia