Ancient monastery corridors adorned with art lead to a serene spa offering chocolate and jade stone massages. Guests can unwind in the beautiful pool area amid lush gardens and colonial architecture. The restaurant serves local cuisine with enchanting live piano music in the evening.
Popular amenities
Pet friendly
Air conditioning
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Located in Antigua Guatemala, Hotel Museo Spa Casa Santo Domingo is in the historical district. Las Capuchinas Convent and Palacio del Ayuntamiento are local landmarks, and travelers looking to shop may want to visit Jade Maya Factory and Museum and Nim Po't Traditional Textiles Center. House of the Giants and La Azotea Cultural Center are also worth visiting. Visit our Antigua Guatemala travel guide
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez, 3001
What's nearby
Central Park
6 min walk - 0.4 miles
Santa Catalina Arch
8 min walk - 0.5 miles
Antigua Guatemala Cathedral
8 min walk - 0.5 miles
Casa Santo Domingo Museum
1 min walk - 0.0 miles
Las Capuchinas Convent
5 min walk - 0.3 miles
Getting around
La Aurora Intl. Airport (GUA)
68 min drive
Restaurants
Clio’s Antigua
3 min walk
Bar El Cabildo
1 min walk
7 Caldos Antigua Guatemala
1 min walk
Cafe Condesa Express
3 min walk
Cafe Sol
1 min walk
About this property
Hotel Museo Spa Casa Santo Domingo
Luxury boutique hotel in the historical district
Close to Casa Santo Domingo Museum and Antigua Guatemala Cathedral, Hotel Museo Spa Casa Santo Domingo provides a poolside bar, a terrace, and a garden. Indulge in a facial, a body wrap, and a body treatment at the onsite spa. At the two on-site restaurants, enjoy breakfast, lunch, dinner, and Fusion cuisine. Enjoy the health club, as well as activities like ziplining. In addition to a hair salon and dry cleaning/laundry services, guests can connect to free WiFi in public areas.
Other perks at this hotel include:
An outdoor pool
Free self parking
Full breakfast (surcharge), a roundtrip airport shuttle (surcharge), and an electric car charging station
Express check-out, ATM/banking services, and meeting rooms
Guest reviews speak highly of the helpful staff and first-rate property condition
Room features
All 132 rooms include comforts such as fireplaces and premium bedding, as well as perks like pillow menus and air conditioning.
Extra conveniences in all rooms include:
Rollaway/extra beds (surcharge) and cribs/infant beds (surcharge)
Daily full breakfast available 7:00 AM to 11:00 AM for a fee: USD 20 per person
2 bars/lounges
2 restaurants
A poolside bar
Restaurants on site
El Refrectorio
El Tenedor Del Cerro
Things to do
Full-service spa
Health club
Outdoor pool
Sauna
Steam room
Ziplining
Family friendly
Crib (surcharge)
Laundry facilities
Outdoor pool
Rollaway/extra bed (surcharge)
Conveniences
24-hour front desk
ATM
Free newspapers in lobby
Guidebooks
Hair salon
Laundry facilities
Luggage storage
Safe at front desk
Water dispenser
Guest services
Concierge services
Dry cleaning/laundry service
Housekeeping (daily)
Tour and ticket assistance
Business services
Business center
Conference space
Meeting rooms
Outdoors
Garden
Terrace
Vegetable garden
Full-service spa
Aromatherapy
Body scrubs
Body wraps
Couples treatment rooms
Facials
Hot tub
Manicures/pedicures
Massage
Sauna
Spa open daily
Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
No elevator
Wheelchair accessible (may have limitations)
Wheelchair-accessible business center
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible registration desk
Wheelchair-accessible restaurant
More
1 building
2 floors
Banquet hall
Built in 1989
Local artist showcase
Smoking not allowed
Some LED lighting used
Room amenities
Bedroom
Crib (surcharge)
Pillow menu
Premium bedding
Rollaway/extra bed (surcharge)
Bathroom
Bathtub or shower
Hair dryer
Private bathroom
Towels provided
Entertainment
42-inch smart TV with premium cable channels
Food and drink
Limited room service
Minibar
Restaurant dining guides
More
Air conditioning
Connecting rooms available
Fireplace
Iron/ironing board
Phone
Safe
Policies
Check-in
Check-in start time: 3:00 PM; Check-in end time: midnight
Early check-in subject to availability
Late check-in subject to availability
Minimum check-in age: 18
Check-out
Check-out before noon
Late check-out subject to availability
A late check-out fee will be charged
Express check-out available
Special check-in instructions
Front desk staff will greet guests on arrival at the property
For any questions, please contact the property using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets allowed for an extra charge of USD 61 per pet, per night
Welcoming dogs only
1 total (up to 25 lbs per pet)
Pets cannot be left unattended
Restrictions apply; for more information contact the property at the number on the booking confirmation
Children and extra beds
Children are welcome
Rollaway/extra beds are available for USD 48.8 per day
Cribs (infant beds) are available for USD 9.76 per day
Property payment types
Important information
Optional extras
Fee for full breakfast: approximately USD 20 per person
Airport shuttle fee: USD 60 per person (one-way)
Pet fee: USD 61 per pet, per night
Late check-out is available for a fee (subject to availability)
Crib (infant bed) fee: USD 9.76 per day
Rollaway bed fee: USD 48.8 per day
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards and cash
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Safety features at this property include a fire extinguisher, a smoke detector, and a first aid kit
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
This property charges a fee of USD 45 per night for use of the sofabed.
We should mention
This property does not have elevators
Reservations are required for massage services and spa treatments; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Guests under 18 years old are not allowed in the spa
Frequently asked questions
Does Hotel Museo Spa Casa Santo Domingo have a pool?
Yes, this property has an outdoor pool.
How much does it cost to stay at Hotel Museo Spa Casa Santo Domingo?
As of Sep 20, 2026, prices found for a 1-night stay for 2 adults at Hotel Museo Spa Casa Santo Domingo on Sep 23, 2026 start from $303, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Hotel Museo Spa Casa Santo Domingo pet-friendly?
Yes, Hotel Museo Spa Casa Santo Domingo allows dogs (limit 1 total) with a maximum weight of up to 25 lbs per pet. There's a fee of USD 61 per pet, per night. Some restrictions may apply, so please contact the property for more details.
How much is parking?
Self parking is free at this property.
What time is check-in at Hotel Museo Spa Casa Santo Domingo?
Check-in start time: 3:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.
What time is check-out at Hotel Museo Spa Casa Santo Domingo?
Check-out is at noon. Late check-out is available for a fee (subject to availability).
Does Hotel Museo Spa Casa Santo Domingo provide a shuttle to the airport?
Yes, there's an airport shuttle. A fee of USD 60 per person applies.
Where is Hotel Museo Spa Casa Santo Domingo located?
Located in Barrio de La Concepción, this luxury hotel is within a 10-minute walk of Casa Santo Domingo Museum, Central Park, and Antigua Guatemala Cathedral. Iglesia y Convento de Santo Domingo and Jade Maya Factory and Museum are just steps away.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Hotel Museo Spa Casa Santo Domingo Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
Room was supper clean and The staff helped with anything I needed . Breakfast was one of my favorite and the spa was perfect after doing a two day hike prior.
The place is the most luxurious hotel in Antigua. It has a museum, good food, exceptional rooms which invite you to rest.
The property exceeded our expectations.
A historic treasure in the heart of Antigua! Loved everything about my stay there. Beautiful rooms, restaurant food was delicious and moderately priced, helpful staff, we felt welcomed and cared for
One in a lifetime experiance, make sure to book a room with access to the spa and breakfast at their restaurant! Great location, at an amazing historical property!
Love this place. Staff always very friendly and attentive. They maintain a very clean property, the rooms, the restaurant and the spa! The Sunday brunch is well worth it with a large selection of food. The spa is a must experience and highly recommend booking the rooms with spa access which makes it well worth it.
The best hotel experience I’ve ever had had. The staff was friendly and helpful. The property grounds were beautiful. And the food at the restaurant was delicious. We loved the spa so much we canceled our entire plans one day just to stay in at the hotel! Couldn’t have had a better stay.
Best hotel in Antigua. Beautifully maintained, staff is very nice and helpful and breakfast was delicious. The rooms are spacious and comfortable while staying true to the aesthetic of the property.
The photos on the website do not do this property justice. Large campus with large dining (website shows only a few tables.) We’ll be back—truly magical.
This is a hotel like no other in the world! Situated in a colonial city it was built around a ruin and made into a 5 star hotel! Any wise and knowledgeable traveler should stay in it and enjoy its different and beautiful settings as well as its service and food! Really excellent!
We had an absolute wonderful time at this hotel!!! We spent almost 3 hours just exploring the displays/museum of the hotel. It is a beautiful hotel, and the staff was beyond excellent and helpful. We loved the room which was like a mini apartment, that staff kept EXTRA clean, and enjoyed the morning/mid day coffee and treats that were put out for guests daily. We will definitely be staying here again for our return trip to Antigua.
If you need a stay in Antigua - this is THE PLACE to be. From the beautifully furnished and decorated rooms, to an excellent spa and restaurant - everything is top notched, thoughtfully designed and aimed for your relaxation and recovery. We can not wait to come back!
The whole property was very clean. Every staff members I asked questions to were very welcoming and helpful. The pool was amazing as well. I really enjoyed the amenities. I e never been to a hotel with a fireplace and I loved it. I didn’t go to the restaurant but it looked very elegant. I would totally stay there again.
"I have been visiting this hotel for years, and it consistently exceeds my expectations. The level of customer service is truly remarkable—the staff goes out of their way to make you feel like family, remembering your preferences and ensuring a seamless stay.
Excellent service, dining, clean rooms, great spa facilities,
Thank you.