Located in Yazoo City, The Main Street Hotel is near a train station. Panther Swamp National Wildlife Area and Delta National Forest reflect the area's natural beauty and area attractions include The Oakes African-American Cultural Center and Triangle Cultural Center. Visit our Yazoo City travel guide
203 S Main Street, Yazoo City, MS, 39194
What's nearby
The Oakes African-American Cultural Center
3 min walk - 0.2 miles
Triangle Cultural Center
6 min walk - 0.4 miles
Panther Swamp National Wildlife Area
27 min drive - 18.4 miles
Canton Courthouse Square
35 min drive - 38.1 miles
Eagle Lake
37 min drive - 33.2 miles
Getting around
Yazoo City Station
5 min walk
Evers Intl. Airport (JAN)
67 min drive
Restaurants
Circle K
5 min drive
McDonald's
5 min drive
El Palenque Mexican Restaurant
12 min walk
Wendy's
4 min drive
Sonic Drive-In
5 min drive
About this property
The Main Street Hotel
Hotel near a train station
The Main Street Hotel provides everything you need. Stay connected with free in-room WiFi.
Additional perks include:
Free self parking
Express check-out and smoke-free premises
Room features
All guestrooms at The Main Street Hotel feature perks such as premium bedding and air conditioning, in addition to amenities like free WiFi.
Extra conveniences in all rooms include:
Bathrooms with shower/tub combinations and hair dryers
Check-in start time: 11:00 AM; Check-in end time: 5:00 PM
Contactless check-in available
Minimum check-in age: 18
Check-out
Check-out before 11 AM
Contactless check-out available
Express check-out available
Special check-in instructions
The front desk is open Monday - Friday (8:00 AM - 5:00 PM)
Guests must contact the property in advance for check-in instructions; front desk staff will greet guests on arrival at the property
This property doesn't offer after-hours check-in
To make arrangements for check-in please contact the property at least 24 hours before arrival using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets not allowed
Children and extra beds
Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available
Property payment types
Important information
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Cashless transactions are available
Frequently asked questions
Is The Main Street Hotel pet-friendly?
No, pets are not allowed at this property.
How much does it cost to stay at The Main Street Hotel?
As of Sep 18, 2026, prices found for a 1-night stay for 2 adults at The Main Street Hotel on Sep 19, 2026 start from $104, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking?
Self parking is free at this property; nearby parking is also free.
What time is check-in at The Main Street Hotel?
Check-in start time: 11:00 AM; Check-in end time: 5:00 PM. After-hours check-in is not available.
What time is check-out at The Main Street Hotel?
Check-out is at 11 AM.
Where is The Main Street Hotel located?
Situated in Yazoo City, this hotel is within a 10-minute walk of The Oakes African-American Cultural Center and Triangle Cultural Center. Baptist Memorial Hospital-Yazoo and Northwest Shopping Center are also within 3 mi (5 km). Yazoo City Station is only a 5-minute walk.
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