481 Properties in Durham, North Carolina, United States of America. January 5, 2026 through January 6, 2026

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A hallway with wooden paneling, a tiled floor, and three spherical light fixtures.

21c Museum Hotel Durham

Downtown Durham

8.48.4 out of 10

Very Goodvery good

1,005 reviews(1,005 reviews)

$170 nightly

The current price is $198 total

$198 total

Total with taxes and fees

We have 1 left at this price

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A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

Comfort Inn & Suites Durham near Duke University

Durham

Breakfast included
Pool

8.68.6 out of 10

Excellentexcellent

1,094 reviews(1,094 reviews)

$119 nightly

The current price is $135 total

$135 total

Total with taxes and fees

We have 3 left at this price

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A hotel room with a large bed, two bedside lamps, a chair, a desk, a heater, and a window with curtains.

University Inn Durham next to Duke University Medical Center

Durham

Fully refundable

Reserve now, pay later

9.09.0 out of 10

Wonderfulwonderful

1,006 reviews(1,006 reviews)

$7 off

$128 nightly

The current price is $145 total

$145 total

Total with taxes and fees

We have 3 left at this price

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Photo gallery for 21c Museum Hotel Durham

21c Museum Hotel Durham

Photo gallery for Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

Photo gallery for University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center