Residence Inn by Marriott Rochester Mayo Clinic Area
3.0 star property
Residence Inn by Marriott Rochester Mayo Clinic Area welcomes travelers with barbecue grills, on-site shopping, and staff that makes everyone feel at home
Choose dates to view prices
Photo gallery for Residence Inn by Marriott Rochester Mayo Clinic Area
Located in Downtown Rochester, this hotel combines comfort with convenience. Guests start their day with breakfast and rooftop views, then explore nearby shops. The manager's reception offers a chance to unwind, while free WiFi and attentive staff enhance the experience.
Popular amenities
Pet friendly
Free WiFi
Air conditioning
Gym
Parking available
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Check-in start time: 4:00 PM; Check-in end time: midnight
Early check-in subject to availability
Late check-in subject to availability
Minimum check-in age: 21
Check-out
Check-out before noon
Late check-out subject to availability
A late check-out fee will be charged
Express check-out available
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets allowed for an extra charge of USD 150 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total pets
Specific rooms only, restrictions apply; pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation
Children and extra beds
Children are welcome
Free rollaway/extra beds
Free cribs are available on request at the property
Property payment types
Important information
Optional extras
Uncovered self parking fee: USD 20 per day (in/out privileges)
Pet fee: USD 150 per accommodation, per stay
Service animals are exempt from fees
Late check-out is available for a fee (subject to availability)
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Guests must contact this property in advance to reserve onsite parking
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
We should mention
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Frequently asked questions
Is Residence Inn by Marriott Rochester Mayo Clinic Area pet-friendly?
Yes, this property allows cats and dogs (limit 2 total). There's a fee of USD 150 per accommodation, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much does it cost to stay at Residence Inn by Marriott Rochester Mayo Clinic Area?
As of May 23, 2026, prices found for a 1-night stay for 2 adults at Residence Inn by Marriott Rochester Mayo Clinic Area on May 31, 2026 start from $206, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking?
Self parking is available for USD 20 per day. Limited spots are available.
What time is check-in at Residence Inn by Marriott Rochester Mayo Clinic Area?
Check-in start time: 4:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.
What time is check-out at Residence Inn by Marriott Rochester Mayo Clinic Area?
Check-out is at noon. Late check-out is available for a fee (subject to availability).
Where is Residence Inn by Marriott Rochester Mayo Clinic Area located?
Located in Downtown Rochester, this hotel is within a 5-minute walk of American Cancer Society Hope Lodge and Mayo Clinic. Shops University Square and Plummer Building are also within 10 minutes.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Reviews
8.4
Very Good
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
We were there for 3 nights while visiting Doctors at Mayo. The location is very good and is connected to the Mayo Subway. The hotel was clean and staff friendly.
Really outstanding. Friendly and accommodating staff allowed me to check in early (post-surgery). So, that was a relief. Check-in otherwise was really quick and efficient. Treated me like a guest. Room was spotless and well furnished, good internet and video/TV service, large screen TV, very comfortable bed, breakfast had great variety and quality ingredients with pleasant breakfast room, and spotless bath and vanity. Everything was perfect. Direct access to Mayo Clinic Subway level was a great help.
The property was a little dated however the room was well appointed and neat. Awesome water pressure. Breakfast was good.
Loxley Francis
Stayed 5 nights in Oct 2024
Verified
8/10 Good
David
Mar 12, 2024
Liked: Cleanliness, staff & service
Conveniently located to Mayo Clinic
We've stayed here numerous times over the last 3 years. I was glad to see that renovations are going to take place, as the rooms are starting to show wear/tear. The sofa was horribly uncomfortable, but the bed was decent. The convenience to the Mayo Clinic is unbeatable, so we will continue to stay here on future trips.
David
Stayed 2 nights in Mar 2024
Verified
10/10 Excellent
Laura
Sep 2, 2024
Liked: Cleanliness, staff & service
Disliked: Property conditions & facilities
I've never been to a more friendly and welcoming hotel. The staff was extremely helpful when there was a room mix up. They were exceptionally kind and accommodating. The hotel needs some updates, chairs were worn, furniture was in need of repair and the water took some time to get hot but i cannot speak highly enough of the wonderful staff.
Despite being under renovation, the room and common areas are clean and well maintained. Very light and pleasant breakfast room and lobby area. Excellent breakfast choices. One huge bonus is the direct connection to the Mayo Clinic via the pedestrian subway, connecting beyond to the Rochester skyway systems. This is a godsend in the winter when temperatures frequently plunge to single digits. I would definitely come back here if using the Mayo facilities. Great find.
William
Stayed 8 nights in Feb 2025
Verified
4/10 Poor
Verified traveler
Apr 24, 2024
Liked: Cleanliness, staff & service, room comfort
Disliked: Property conditions & facilities
Our room was next to the elevators, so we had to listen to them rumble at all hours. The furniture was worn and shabby, and we could find no USB ports to charge our devices until the last day when we found some hiding in the alarm clock. The bed was comfortable. The complimentary breakfast was in general mediocre, although the egg dishes were both excellent.
Verified traveler
Stayed 2 nights in Apr 2024
Verified
8/10 Good
Verified traveler
Oct 1, 2023
Liked: Cleanliness, staff & service, room comfort
Close to Mayo Clinic
The facility is getting aged and room had an odor to it. Informed front desk of odor and they said it would be addressed, but they also noted that a facility update is planned for the near future.
The kitchen was a nice amenity for our stay. Breakfast was great and staff was super friendly and helpful. The subway connection to the Mayo Clinic is awesome and convenient.
Everything was very clean and all the staff was very nice, the only bummer is they are building a parking garage behind the hotel that blocks the view from the patio area but they still advertise with a view that doesn’t exist anymore