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Photo gallery for 21C Museum Hotel St Louis

A modern lobby with a large glass sphere, seating areas, and a reception desk.
Spa
Bar (on property)
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.
Luxury
Property class: 4.5

21C Museum Hotel St Louis

Luxury hotel near Enterprise Center

Close to City Museum and St. Louis Union Station, 21C Museum Hotel St Louis provides a coffee shop/cafe, dry cleaning/laundry services, and a bar. Treat yourself to a massage or other spa services. In addition to a gym and a business center, guests can connect to free in-room WiFi.

Family-friendly highlights for your trip

  • Loved by families

    This property received multiple 10/10 ratings from families.

  • Dive into relaxation

    Unwind in the top-rated pool, your perfect spot for relaxation.

  • Relax in the indoor pool

    A rare find in this area - enjoy a swim, whatever the weather.

  • Endless exploration awaits

    Guests love the top-rated location, steps from iconic landmarks and sights.

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