Find hotels in Serra Mesa, San Diego from $94

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Discover 8,465 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Wyndham San Diego Bayside
4.0 star property
8.2 out of 10, Very Good, (5882)
"Beautiful and convenient hotel"
The price is $161
$182 total
includes taxes & fees
May 27 - May 28
Wyndham San Diego Bayside
Aerial view
Paradise Point Resort & Spa
4.0 star property
8.4 out of 10, Very Good, (1814)
"The staff was extremely courteous and friendly. This is an enjoyable location where you can have a great time with your family and feel free and safe. I highly recommend it. "
The price is $209
$281 total
includes taxes & fees
May 27 - May 28
Paradise Point Resort & Spa
Aerial view
The Dana on Mission Bay
3.5 star property
8.8 out of 10, Excellent, (2462)
"We had the marina view, it was amazing and so peaceful. Highly recommend this hotel!"
The price is $179
$202 total
includes taxes & fees
May 27 - May 28
The Dana on Mission Bay
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Exterior
Omni San Diego Hotel
4.0 star property
9.0 out of 10, Wonderful, (1887)
"I love how everything is accessible. By train, or by walking. Staff was very friendly, answered all my questions and catered to my specific requests. The remodel looks great! Whenever we are in San Diego, we ONLY stay at the Omni! Thanks team!"
The price is $212
$272 total
includes taxes & fees
Jun 13 - Jun 14
Omni San Diego Hotel
Outdoor pool
Mission Bay Inn San Diego
2.5 star property
7.4 out of 10, Good, (1005)
"Positive experience."
The price is $94
$105 total
includes taxes & fees
May 27 - May 28
Mission Bay Inn San Diego
Outdoor pool, sun loungers
Hilton San Diego Bayfront
4.0 star property
8.4 out of 10, Very Good, (1484)
"Walking distance to the convention center"
The price is $168
$237 total
includes taxes & fees
May 27 - May 28
Hilton San Diego Bayfront
2 outdoor pools, sun loungers
Best Western Plus Island Palms Hotel & Marina
3.0 star property
8.8 out of 10, Excellent, (1583)
"This was a beautiful place to celebrate my anniversary with my significant other. I had stayed here before on a family trip and it was beautiful and coming back was amazing. "
The price is $159
$179 total
includes taxes & fees
May 27 - May 28
Best Western Plus Island Palms Hotel & Marina
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
7.8 out of 10, Good, (1911)
"It was right next to the highway so no matter where we were going it was convenient. There was a nice pool area. The only thing I didnt like was my loud upstairs neighbor, lol"
The price is $98
$111 total
includes taxes & fees
May 27 - May 28
Days Inn by Wyndham San Diego Hotel Circle
Courtyard
DoubleTree by Hilton San Diego - Del Mar
4.0 star property
7.2 out of 10, Good, (1027)
"It was clean and quiet."
The price is $138
$155 total
includes taxes & fees
May 30 - May 31
DoubleTree by Hilton San Diego - Del Mar
Rooftop terrace
Palihotel San Diego
4.0 star property
8.8 out of 10, Excellent, (515)
"Super cute. Great rooftop "
The price is $110
$152 total
includes taxes & fees
May 27 - May 28
Palihotel San Diego
Lobby
Gaslamp Plaza Suites
3.5 star property
8.8 out of 10, Excellent, (1003)
"Great property "
The price is $109
$120 total
includes taxes & fees
May 27 - May 28
Gaslamp Plaza Suites
Lobby
Catamaran Resort and Spa
4.0 star property
7.8 out of 10, Good, (1105)
"The resort was very nice and well maintained. Enjoyed the beach and walkways. Good restaurants and bar."
The price is $229
$302 total
includes taxes & fees
May 28 - May 29
Catamaran Resort and Spa
Seasonal outdoor pool, a heated pool
Ocean Villa Inn
2.5 star property
8.2 out of 10, Very Good, (1001)
"would recommend! loved it "
The price is $107
$118 total
includes taxes & fees
May 28 - May 29
Ocean Villa Inn
Balcony view
La Jolla Shores Hotel
3.0 star property
8.8 out of 10, Excellent, (1252)
"Property need a major renovation it was built in 1970 and i dont think they did much renovation to it . "
The price is $379
$463 total
includes taxes & fees
Jun 18 - Jun 19
La Jolla Shores Hotel
Exterior
Loews Coronado Bay Resort
4.0 star property
8.6 out of 10, Excellent, (1050)
"Beautiful resort. Will stay again. Only complaint would be the short hours at pool bar and grill. "
The price is $219
$289 total
includes taxes & fees
May 27 - May 28
Loews Coronado Bay Resort
Front of property
Pendry San Diego
5.0 star property
9.4 out of 10, Exceptional, (1001)
"Full service hotel, and fantastic location. Accommodating staff, great timing options right in the hotel, as well as ample dining in the gaslamp district."
The price is $293
$380 total
includes taxes & fees
Jun 7 - Jun 8
Pendry San Diego
Water view
Kona Kai San Diego
4.0 star property
8.4 out of 10, Very Good, (949)
"Great staff"
The price is $239
$320 total
includes taxes & fees
May 27 - May 28
Kona Kai San Diego
Pillowtop beds, in-room safe, desk, blackout drapes
Holiday Inn Express San Diego Downtown, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (1005)
"I truly enjoyed the free breakfast that was available every morning. They had a nice variety of options. I also appreciated the great customer service at this hotel. Chris specifically was very personable and made some great recommendations for dinners! This hotel is conveniently located in the downtown area and parking is also reasonable. "
The price is $159
$179 total
includes taxes & fees
May 27 - May 28
Holiday Inn Express San Diego Downtown, an IHG Hotel
Outdoor pool, pool umbrellas, sun loungers
Handlery Hotel
3.5 star property
7.8 out of 10, Good, (1584)
"The hotel was a great value and the room I stayed in was modern, clean and comfortable. Front desk staff were friendly and the bartender was also very nice."
The price is $116
$131 total
includes taxes & fees
May 30 - May 31
Handlery Hotel
Bar (on property)
Sheraton Mission Valley San Diego Hotel
4.0 star property
8.4 out of 10, Very Good, (1097)
"Staff was very amazing! Super friendly. Only thing I did not like was the room we were placed in a room were it’s convenient for someone with disabilities but not for us. "
The price is $134
$151 total
includes taxes & fees
May 29 - May 30
Sheraton Mission Valley San Diego Hotel
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Other neighborhoods around Serra Mesa

Hotels in top San Diego neighborhoods Learn more about Serra Mesa
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

From historic streets, waterfront parks and baseball, to performing arts venues, nightlife zones and art and maritime museums, this is the cultural hub of San Diego.

Find hotels in Downtown San Diego

Serra Mesa Travel Info

Number of reviews
30,637
Location
San Diego, United States of America
Similar neighborhoods
Central San Diego, Mission Valley West and Midway District
Accommodation
8,465 hotels
Known landmarks
Boomers San Diego, Diversionary Theatre and Snapdragon Stadium
Hotels with golf
Courtyard by Marriott San Diego Central, Four Points by Sheraton San Diego and Extended Stay America Suites San Diego Fashion Valley
Lowest price
$94
Highest price
$379

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

Where is the best place to stay in Serra Mesa?

For your stay in Serra Mesa, Cozy 2 bedroom unit with pool is one of the top choices based on our traveler data. Other good choices for your stay in the area include Centrally Located San Diego Condo w/Hot Tub & Pool and Central location - 3br/2ba. Stay weekly. Clean, safe, quiet. .

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 29 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

Recent reviews of Serra Mesa hotels

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

5/5 Excellent
"Helpful staff and good facilities."
A verified traveler stayed at Manchester Grand Hyatt San Diego
Posted 14 hours ago
Manchester Grand Hyatt San Diego