Find hotels in Otay Mesa, San Diego from $74

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Discover 4,438 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

3 outdoor pools
Rosarito Beach Hotel
3.0 star property
7.8 out of 10, Good, (1001)
"I like services"
The price is $118
$134 total
includes taxes & fees
May 23 - May 24
Rosarito Beach Hotel
Outdoor pool
Grand Hotel Tijuana
3.5 star property
8.8 out of 10, Excellent, (2478)
"Amazing stay, service very attentive. Must have brunch . The customer service at brunch is very friendly . Feeling like home"
The price is $122
$138 total
includes taxes & fees
Jun 2 - Jun 3
Grand Hotel Tijuana
Exterior
Loews Coronado Bay Resort
4.0 star property
8.6 out of 10, Excellent, (1049)
"Beautiful property. Front desk woman (Cindy) was the most nasty, condescending person I have ever met. Loews should do themselves a favor and put her somewhere far away from any human contact."
The price is $219
$289 total
includes taxes & fees
May 27 - May 28
Loews Coronado Bay Resort
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Standard Room, 1 King Bed | Individually decorated, bed sheets
Hotel Festival Plaza Playas Rosarito
3.0 star property
7.0 out of 10, Good, (1199)
"Nice place very central to all the activities, breakfast was very good too "
The price is $82
$93 total
includes taxes & fees
May 27 - May 28
Hotel Festival Plaza Playas Rosarito
Property entrance
Hotel Ticuán
3.5 star property
9.0 out of 10, Wonderful, (1720)
"It was a great stay,and had a good time."
The price is $87
$101 total
includes taxes & fees
May 23 - May 24
Hotel Ticuán
Exterior
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel
2.5 star property
7.2 out of 10, Good, (1143)
"Excellent "
The price is $95
$107 total
includes taxes & fees
May 27 - May 28
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel
Terrace/patio
Quartz Hotel & SPA
4.5 star property
9.0 out of 10, Wonderful, (1000)
"loved this place !!"
The price is $163
$184 total
includes taxes & fees
May 26 - May 27
Quartz Hotel & SPA
Lobby
Del Mar Inn Rosarito
3.0 star property
7.8 out of 10, Good, (902)
"Limited parking, i had to park outside on the major street "
The price is $77
$87 total
includes taxes & fees
Jun 5 - Jun 6
Del Mar Inn Rosarito
Outdoor pool
Hotel Lucerna Tijuana
4.5 star property
8.2 out of 10, Very Good, (1004)
"Staff very friendly"
The price is $162
$183 total
includes taxes & fees
Jun 9 - Jun 10
Hotel Lucerna Tijuana
Lobby
Motel 6 San Ysidro, CA - San Diego - Border
2.0 star property
6.8 out of 10, (1001)
"Affordable we stay there before driving into Mexico 🇲🇽 "
The price is $74
$84 total
includes taxes & fees
May 27 - May 28
Motel 6 San Ysidro, CA - San Diego - Border
Terrace/patio
Holiday Inn Tijuana Zona Rio, an IHG Hotel
3.5 star property
8.4 out of 10, Very Good, (1326)
"Very nice, near a mall, wonderful staff "
The price is $99
$112 total
includes taxes & fees
Jun 16 - Jun 17
Holiday Inn Tijuana Zona Rio, an IHG Hotel
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Desk, blackout drapes, iron/ironing board, free WiFi
SureStay Plus Hotel by Best Western Chula Vista West
2.5 star property
7.6 out of 10, Good, (629)
"Very nice room, but not a nice area. Loved the comfy beds tho. "
The price is $104
$114 total
includes taxes & fees
May 23 - May 24
SureStay Plus Hotel by Best Western Chula Vista West
Front of property
Sand Castle Inn
2.5 star property
8.4 out of 10, Very Good, (422)
"Nice little hotel located across the street from the beach. Parking is a little cramped "
The price is $164
$187 total
includes taxes & fees
May 27 - May 28
Sand Castle Inn
Premium bedding, pillowtop beds, in-room safe, individually decorated
Hotel Real del Río
3.5 star property
9.0 out of 10, Wonderful, (1000)
"It’s was very clean and comfortable. I highly recommend it. "
The price is $97
$110 total
includes taxes & fees
Jun 3 - Jun 4
Hotel Real del Río
Exterior
City Express by Marriott Rosarito
3.0 star property
7.2 out of 10, Good, (1001)
"There was no hot water 🚿 on shower Sink was clogged up- curtains broke "
The price is $80
$91 total
includes taxes & fees
Jun 3 - Jun 4
City Express by Marriott Rosarito
Standard Double Room | Desk, laptop workspace, blackout drapes, iron/ironing board
Baja Inn Hoteles Rio
3.5 star property
8.2 out of 10, Very Good, (1000)
"Las personas que laboran muy amables y respetuosas el hotel muy limpio "
The price is $95
$108 total
includes taxes & fees
May 27 - May 28
Baja Inn Hoteles Rio
Lobby lounge
Fairfield Inn & Suites by Marriott Tijuana
3.5 star property
9.2 out of 10, Wonderful, (1000)
"I’ve been staying here for three years and have never had a bad experience. "
The price is $104
$118 total
includes taxes & fees
May 31 - Jun 1
Fairfield Inn & Suites by Marriott Tijuana
Lobby lounge
City Express by Marriott Tijuana Río
3.0 star property
8.2 out of 10, Very Good, (1000)
"Nice to have Security in the lobby and be a deterrent but Security needs to be friendly with guests during the stay."
The price is $109
$124 total
includes taxes & fees
May 27 - May 28
City Express by Marriott Tijuana Río
Outdoor pool
Marriott Hotel Tijuana
4.5 star property
8.4 out of 10, Very Good, (1004)
"."
The price is $125
$141 total
includes taxes & fees
May 31 - Jun 1
Marriott Hotel Tijuana
Outdoor pool
Gamma Tijuana
3.5 star property
7.8 out of 10, Good, (1000)
"Good "
The price is $107
$121 total
includes taxes & fees
Jun 16 - Jun 17
Gamma Tijuana
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Otay Mesa

Hotels in top San Diego neighborhoods Learn more about Otay Mesa
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

From historic streets, waterfront parks and baseball, to performing arts venues, nightlife zones and art and maritime museums, this is the cultural hub of San Diego.

Find hotels in Downtown San Diego

Otay Mesa Travel Info

Number of reviews
21,844
Location
San Diego, United States of America
Similar neighborhoods
Central San Diego, Mission Valley West and Midway District
Accommodation
4,438 hotels
Hotels with connecting rooms
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel and Quality Suites San Diego Otay Mesa
Lowest price
$74
Highest price
$219

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Quality Suites San Diego Otay Mesa is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel.

How many hotels will I be able to find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodations, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

Recent reviews of Otay Mesa hotels

Paradise Point Resort & Spa

Paradise Point Resort & Spa

5/5 Excellent
"The staff was extremely courteous and friendly. This is an enjoyable location where you can have a great time with your family and feel free and safe. I highly recommend it. "
A verified traveler stayed at Paradise Point Resort & Spa
Posted 3 hours ago
Paradise Point Resort & Spa