Find hotels in East Main Street, Grand Junction

Start date: Check-in selected.
To Date
End date: Check-out

    Upfront pricing

    Our total price for your stay includes taxes and fees

    Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 21 - Oct 22
Tomorrow
Oct 22 - Oct 23
This weekend
Oct 24 - Oct 26
Next weekend
Oct 31 - Nov 2

Filter by

Guest rating
Guest rating
Star rating

Discover East Main Street hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Free daily continental breakfast
Super 8 by Wyndham Grand Junction Colorado
Super 8 by Wyndham Grand Junction Colorado
2.0 star property
7.4 out of 10, Good, (1027)
"Will stay again "
United States
Charles
$60 nightly
The price is $68
Nov 9 - Nov 10
Total with taxes and fees
Super 8 by Wyndham Grand Junction Colorado
Restaurant
Tru by Hilton Grand Junction Downtown
Tru by Hilton Grand Junction Downtown
2.5 star property
9.2 out of 10, Wonderful, (919)
"Would stay again."
United States
Craig
$99 nightly
The price is $114
Nov 11 - Nov 12
Total with taxes and fees
Tru by Hilton Grand Junction Downtown
Exterior
La Quinta Inn & Suites by Wyndham Fruita
La Quinta Inn & Suites by Wyndham Fruita
3.0 star property
8.4 out of 10, Very Good, (1001)
"Good overnight stay"
United States
Lee
$84 nightly
The price is $96
Nov 4 - Nov 5
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Fruita
Free continental breakfast
La Quinta Inn & Suites by Wyndham Grand Junction
La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
8.8 out of 10, Excellent, (2619)
"Very clean, friendly staff and good breakfast"
United States
Michele
$76 nightly
The price is $87
Oct 28 - Oct 29
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Grand Junction
Billiards
Clarion Inn Grand Junction
Clarion Inn Grand Junction
2.5 star property
8.6 out of 10, Excellent, (1662)
"Clean room and friendly staff"
United States
Minh
$80 nightly
The price is $92
Nov 7 - Nov 8
Total with taxes and fees
Clarion Inn Grand Junction
Reception
Ramada by Wyndham Grand Junction
Ramada by Wyndham Grand Junction
2.5 star property
8.4 out of 10, Very Good, (1827)
"I would definitely stay here again"
United States
Debra
$62 nightly
The price is $71
Nov 9 - Nov 10
Total with taxes and fees
Ramada by Wyndham Grand Junction
Exterior
WoodSpring Suites Grand Junction
WoodSpring Suites Grand Junction
2.5 star property
6.4 out of 10, (879)
"I enjoy my stay here so much, I have decided to make it my long term resudence for a while. "
United States
Heather
$72 nightly
The price is $83
Oct 22 - Oct 23
Total with taxes and fees
WoodSpring Suites Grand Junction
Rooftop terrace
Hotel Maverick
Hotel Maverick
4.0 star property
9.6 out of 10, Exceptional, (1008)
"Great hotel."
United States
Anthony
$179 nightly
The price is $205
Nov 2 - Nov 3
Total with taxes and fees
Hotel Maverick
Exterior
Holiday Inn and Suites Grand Junction by IHG
Holiday Inn and Suites Grand Junction by IHG
3.0 star property
8.6 out of 10, Excellent, (1007)
"Great hotel very close to airport. Clean property and very friendly staff. Would definitely stay here again, if ever in the area. "
United States
Deborah
$96 nightly
The price is $110
Nov 9 - Nov 10
Total with taxes and fees
Holiday Inn and Suites Grand Junction by IHG
Lobby
Quality Inn Grand Junction near University
Quality Inn Grand Junction near University
3.0 star property
8.6 out of 10, Excellent, (1023)
"Great room, reasonable price, friendly staff."
United States
Paul
$84 nightly
The price is $96
Nov 3 - Nov 4
Total with taxes and fees
Quality Inn Grand Junction near University
Terrace/patio
Home2 Suites by Hilton Grand Junction Northwest
Home2 Suites by Hilton Grand Junction Northwest
3.0 star property
9.2 out of 10, Wonderful, (852)
"Clean room, friendly staff, great location!"
United States
Brandee
$146 nightly
The price is $168
Oct 31 - Nov 1
Total with taxes and fees
Home2 Suites by Hilton Grand Junction Northwest
Exterior
Hampton Inn Grand Junction Downtown/Historic Main Street
Hampton Inn Grand Junction Downtown/Historic Main Street
2.5 star property
8.8 out of 10, Excellent, (1010)
"Love being in downtown Grand Junction. The hotel was very nice."
United States
Sherri
$95 nightly
The price is $109
Nov 2 - Nov 3
Total with taxes and fees
Hampton Inn Grand Junction Downtown/Historic Main Street
Exterior
Holiday Inn Express & Suites Grand Junction by IHG
Holiday Inn Express & Suites Grand Junction by IHG
2.5 star property
8.6 out of 10, Excellent, (1006)
"Very clean, friendly staff, excellent breakfast "
United States
Lisa
$146 nightly
The price is $167
Oct 31 - Nov 1
Total with taxes and fees
Holiday Inn Express & Suites Grand Junction by IHG
Lobby
Comfort Inn & Suites
Comfort Inn & Suites
2.5 star property
8.4 out of 10, Very Good, (1024)
"Very nice place to stay."
United States
Charles
$79 nightly
The price is $90
Nov 2 - Nov 3
Total with taxes and fees
Comfort Inn & Suites
Terrace/patio
Doubletree Hotel Grand Junction
Doubletree Hotel Grand Junction
4.0 star property
8.0 out of 10, Very Good, (1011)
"Property was very nice great staff vet intentive to guests needs "
United States
Shane
$87 nightly
The price is $100
Nov 16 - Nov 17
Total with taxes and fees
Doubletree Hotel Grand Junction
Terrace/patio
Courtyard by Marriott Grand Junction
Courtyard by Marriott Grand Junction
3.0 star property
8.4 out of 10, Very Good, (1000)
"Nice place."
United States
Chris
$98 nightly
The price is $112
Nov 9 - Nov 10
Total with taxes and fees
Courtyard by Marriott Grand Junction
Property amenity
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
3.5 star property
9.0 out of 10, Wonderful, (1008)
"Very nice family hotel with good breakfast."
United States
Margarita
$143 nightly
The price is $164
Nov 2 - Nov 3
Total with taxes and fees
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
Dinner served
Wine Country Inn Palisade
Wine Country Inn Palisade
3.5 star property
9.6 out of 10, Exceptional, (1025)
"We loved the location near the wineries. Great place to stay!!"
United States
Sara
$159 nightly
The price is $177
Nov 1 - Nov 2
Total with taxes and fees
Wine Country Inn Palisade
Room, 2 Double Beds, Accessible, Non Smoking | Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi
Econo Lodge Grand Junction North
Econo Lodge Grand Junction North
2.0 star property
8.4 out of 10, Very Good, (1006)
"We loved the stay, location helped with both gas and food! "
United States
Erandy
$61 nightly
The price is $70
Nov 12 - Nov 13
Total with taxes and fees
Econo Lodge Grand Junction North
Property entrance
Best Western Grande River Inn & Suites
Best Western Grande River Inn & Suites
2.5 star property
9.0 out of 10, Wonderful, (774)
"Clean facility, convenient location, pleasant & efficient staff "
United States
Jerry
$101 nightly
The price is $106
Nov 17 - Nov 18
Total with taxes and fees
Best Western Grande River Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in East Main Street

Find the best East Main Street areas and neighborhoods for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Horizon Drive District

While there might not be top attractions in Horizon Drive District, you can explore the larger area and discover places like Canyon View Park and Bananas Fun Park.

Pear Park

If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.

Top East Main Street Hotel Reviews

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

10/10 Excellent
"Clean"
Sharon 1-night trip
Posted 3 days ago
La Quinta Inn & Suites by Wyndham Grand Junction

Frequently asked questions

What's it like in East Main Street?
Travelers will be sure to enjoy their time in Grand Junction's East Main Street neighborhood.
Where is the best hotel for a stay in East Main Street?
For your stay in East Main Street, Grand Junction Vacation Rental w/ Fire Pit! is one of the top choices based on our traveler data. Other good choices for your stay in the area include Adventure Home Base - 7 Blocks to Downtown! and Launch your Colorado adventures – Historic Downtown convenience.
How many hotels will I be able to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 22 East Main Street hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get top deals in East Main Street.
Where can I learn more about changing or cancelling my trip to East Main Street?
To find more details about updating your trip to East Main Street or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Grand Junction neighborhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens, and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.