Find hotels in East Main Street, Grand Junction

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Discover East Main Street hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Restaurant
Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown

2.5 star property
Historic Grand Junction, 0.9 mi from East Main Street
9.2 out of 10, Wonderful, (950)
"Great location, helpful staff, nice rooms"
United States
Mary
$79 nightly
The price is $91
Nov 30 - Dec 1
Total with taxes and fees
Tru by Hilton Grand Junction Downtown
Free daily continental breakfast
Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado

2.0 star property
Horizon Drive District, 3 mi from East Main Street
7.4 out of 10, Good, (1011)
"Check-in was quick and efficient. The housekeeping staff were attentive and efficient, as well. The location is close to many eateries and is centrally located. Overall, my stay was pleasant."
United States
Stephen
$55 nightly
The price is $63
Nov 24 - Nov 25
Total with taxes and fees
Super 8 by Wyndham Grand Junction Colorado
Free continental breakfast
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

3.0 star property
Horizon Drive District, 3.3 mi from East Main Street
8.8 out of 10, Excellent, (2660)
"Friendly staff and clean rooms"
United States
Travis
$71 nightly
The price is $82
Nov 24 - Nov 25
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Grand Junction
Exterior
La Quinta Inn & Suites by Wyndham Fruita

La Quinta Inn & Suites by Wyndham Fruita

3.0 star property
11.7 mi from East Main Street
8.4 out of 10, Very Good, (1006)
"Great stay as always here. Nice rooms, a good breakfast, and a great price."
United States
Sam
$80 nightly
The price is $91
Dec 3 - Dec 4
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Fruita
Breakfast served
Grand Vista Hotel

Grand Vista Hotel

3.5 star property
Horizon Drive District, 3.4 mi from East Main Street
8.2 out of 10, Very Good, (3437)
"Great place to stay, front desk was also great!"
United States
Mark
$60 nightly
The price is $69
Nov 24 - Nov 25
Total with taxes and fees
Grand Vista Hotel
Rooftop terrace
Hotel Maverick

Hotel Maverick

4.0 star property
Capitol Hill, 1 mi from East Main Street
9.6 out of 10, Exceptional, (1005)
"Excellent place to stay in Grand Junction. "
United States
Steve
$169 nightly
The price is $194
Nov 30 - Dec 1
Total with taxes and fees
Hotel Maverick
Terrace/patio
Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest

3.0 star property
24 Road Corridor, 3.6 mi from East Main Street
9.2 out of 10, Wonderful, (862)
"Clean room, friendly staff, great location!"
United States
Brandee
$127 nightly
The price is $146
Nov 30 - Dec 1
Total with taxes and fees
Home2 Suites by Hilton Grand Junction Northwest
Reception
Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction

2.5 star property
Horizon Drive District, 3.3 mi from East Main Street
8.4 out of 10, Very Good, (1851)
"We very much enjoyed our stay there!"
United States
Kathryn
$62 nightly
The price is $71
Nov 24 - Nov 25
Total with taxes and fees
Ramada by Wyndham Grand Junction
Billiards
Clarion Inn Grand Junction

Clarion Inn Grand Junction

2.5 star property
Horizon Drive District, 3.3 mi from East Main Street
8.4 out of 10, Very Good, (1678)
"Best stay in Grand Junction!"
United States
Hal
$77 nightly
The price is $88
Nov 30 - Dec 1
Total with taxes and fees
Clarion Inn Grand Junction
Exterior
WoodSpring Suites Grand Junction

WoodSpring Suites Grand Junction

2.5 star property
24 Road Corridor, 3.7 mi from East Main Street
6.4 out of 10, (889)
"I enjoy my stay here so much, I have decided to make it my long term resudence for a while. "
United States
Heather
$55 nightly
The price is $63
Nov 24 - Nov 25
Total with taxes and fees
WoodSpring Suites Grand Junction
Exterior
Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG

3.0 star property
Horizon Drive District, 3.3 mi from East Main Street
8.6 out of 10, Excellent, (1005)
"Staff was friendly and helpful, the rooms were clean and spacious. Great location too, and good breakfast. "
United States
Kate
$91 nightly
The price is $105
Nov 30 - Dec 1
Total with taxes and fees
Holiday Inn & Suites Grand Junction by IHG
Exterior
Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street

2.5 star property
Historic Grand Junction, 0.9 mi from East Main Street
8.8 out of 10, Excellent, (1001)
"Love being in downtown Grand Junction. The hotel was very nice."
United States
Sherri
$87 nightly
The price is $100
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Grand Junction Downtown/Historic Main Street
Lobby
Comfort Inn & Suites

Comfort Inn & Suites

2.5 star property
11.5 mi from East Main Street
8.4 out of 10, Very Good, (1014)
"Cool place to stay"
United States
Russell
$70 nightly
The price is $80
Nov 30 - Dec 1
Total with taxes and fees
Comfort Inn & Suites
Lobby
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

3.0 star property
Horizon Drive District, 3 mi from East Main Street
8.6 out of 10, Excellent, (1009)
"Stsffs were courteous, clean room, amenities good and breakfast was good. It was a quiet area and Parking lot is good. "
United States
Rafina
$70 nightly
The price is $80
Nov 24 - Nov 25
Total with taxes and fees
Quality Inn Grand Junction near University
Property amenity
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.

3.5 star property
Historic Grand Junction, 0.9 mi from East Main Street
9.0 out of 10, Wonderful, (1003)
"Very nice family hotel with good breakfast."
United States
Margarita
$126 nightly
The price is $144
Dec 1 - Dec 2
Total with taxes and fees
SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
Terrace/patio
Courtyard by Marriott Grand Junction

Courtyard by Marriott Grand Junction

3.0 star property
Horizon Drive District, 3.5 mi from East Main Street
8.4 out of 10, Very Good, (1001)
"Room is clean and walking distance to the airport. "
United States
JIN
$93 nightly
The price is $107
Nov 30 - Dec 1
Total with taxes and fees
Courtyard by Marriott Grand Junction
Terrace/patio
Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction

4.0 star property
Horizon Drive District, 3.1 mi from East Main Street
8.0 out of 10, Very Good, (1002)
"Very clean and friendly staff! Restaurant had excellent food and service! "
United States
Holly
$93 nightly
The price is $106
Dec 14 - Dec 15
Total with taxes and fees
Doubletree Hotel Grand Junction
Dinner served
Wine Country Inn Palisade

Wine Country Inn Palisade

3.5 star property
10.6 mi from East Main Street
9.6 out of 10, Exceptional, (1004)
"We loved the location near the wineries. Great place to stay!!"
United States
Sara
$154 nightly
The price is $172
Nov 26 - Nov 27
Total with taxes and fees
Wine Country Inn Palisade
Exterior
Holiday Inn Express & Suites Grand Junction by IHG

Holiday Inn Express & Suites Grand Junction by IHG

2.5 star property
24 Road Corridor, 3.7 mi from East Main Street
8.6 out of 10, Excellent, (1004)
"We enjoyed the breakfast staff"
Canada
Andrea
$156 nightly
The price is $179
Nov 28 - Nov 29
Total with taxes and fees
Holiday Inn Express & Suites Grand Junction by IHG
Lobby
Comfort Inn Grand Junction I-70

Comfort Inn Grand Junction I-70

2.5 star property
Horizon Drive District, 3.3 mi from East Main Street
8.6 out of 10, Excellent, (1007)
"I liked the hotel nice and clean modern furnishings "
United States
Margaret
$77 nightly
The price is $88
Dec 2 - Dec 3
Total with taxes and fees
Comfort Inn Grand Junction I-70
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Main Street

Find the best East Main Street areas and neighborhoods for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Pear Park

If you're spending some time in Pear Park, Colorado River and James M. Robb – Colorado River State Park are top sights worth seeing.

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Horizon Drive District

While there might not be top attractions in Horizon Drive District, you can explore the larger area and discover places like Grand Junction Motor Speedway and Canyon View Park.

Top East Main Street Hotel Reviews

Comfort Inn Grand Junction I-70

Comfort Inn Grand Junction I-70

10/10 Excellent
"Room was like new"
Mark 1-night trip
Posted 4 days ago
Comfort Inn Grand Junction I-70

Frequently asked questions

What's it like in East Main Street?
Travelers will be sure to enjoy their time in Grand Junction's East Main Street neighborhood.
Where is the best hotel for a stay in East Main Street?
Based on our traveler data, Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars. is one of the top choices for your stay in East Main Street. This guesthouse offers private balconies and a fitness center. Other good choices for your stay in the area include Grand Junction Vacation Rental w/ Fire Pit! and Launch your Colorado adventures – Historic Downtown convenience.
How many hotels will I be able to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 22 East Main Street hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get top deals in East Main Street.
Where can I learn more about changing or cancelling my trip to East Main Street?
To find more details about updating your trip to East Main Street or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Grand Junction neighborhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens, and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.