Featured car rental suppliers
Compare from agencies
Change your mind: penalty-free cancellation on many/select car rentals
Treat yourself: One Key members save 10% or more on over 1 million car rentals
Shop Smart: Compare car suppliers and package your flight, hotel, and car to save
Top Car Deals in Panama City
Economy
$38
Special
$46
Compact
$46
Midsize
$48
Standard
$50
Fullsize
$52
Midsize Elite
$60
Premium
$67
Mini Van
$81
Standard Elite SUV
$87
Luxury
$90
Premium Elite SUV
$139
Fullsize Elite Special
$246
Luxury Elite SUV
$304
* Price found within the past 60 days. Click for updated prices.
Frequently asked questions
Car Rental Information
SUV, Full Size, Economy | |
$38 | |
$46 | |
$48 | |
Airport Transportation | |
Airport Car Rentals |
Finding the cheapest car rentals in Panama City
Using our Search Wizard
If the deals that are available on our page do not suit your needs, then enter Panama City into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Panama City and provide you with a list of the cheapest options, with no added fees.
Renting a car in Panama City
Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Panama City. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.
Expected prices in Panama City
Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $38.
Flexibility & Cancellation
Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.
We all love being rewarded
One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.
Car classes available from Expedia in 2024
The classes of vehicles available will change depending on your chosen location.
Neighborhoods in Panama City
Cities near Panama City
- Car rentals in Panama City Beach
- Car rentals in Santa Rosa Beach
- Car rentals in Port St. Joe
- Car rentals in Highway 30A
- Car rentals in Cape San Blas
- Car rentals in Marianna
- Car rentals in West Panama City Beach
- Car rentals in Mexico Beach
- Car rentals in Fort Walton Beach - Destin
- Car rentals in Seacrest
Car Rental Deals in Top Destinations
- Car rentals in Las Vegas
- Car rentals in New York
- Car rentals in Orlando
- Car rentals in London
- Car rentals in Paris
- Car rentals in Cancun
- Car rentals in Miami
- Car rentals in Los Angeles
- Car rentals in Rome
- Car rentals in Punta Cana
- Car rentals in Riviera Maya
- Car rentals in Barcelona
- Car rentals in San Francisco
- Car rentals in San Diego County
- Car rentals in Oahu
- Car rentals in Chicago
Car Rentals Suppliers in Panama City
- Alamo Rent A Car car rentals in Panama City
- Budget car rentals in Panama City
- Enterprise car rentals in Panama City
- Hertz car rentals in Panama City
- Thrifty Car Rental car rentals in Panama City
- Avis car rentals in Panama City
- Dollar Rent A Car car rentals in Panama City
- Sixt car rentals in Panama City
- National car rentals in Panama City
- Europcar car rentals in Panama City
Find Other Car Classes in Panama City
- Mini car rentals in Panama City
- Economy car rentals in Panama City
- Midsize car rentals in Panama City
- Fullsize car rentals in Panama City
- Luxury car rentals in Panama City
- Convertible car rentals in Panama City
- Minivan car rentals in Panama City
- Van car rentals in Panama City
- Pickup car rentals in Panama City
- Sportscar car rentals in Panama City
Top Hotels in Panama City
- Country Inn & Suites by Radisson, Panama City, FL
- La Quinta Inn & Suites by Wyndham Panama City
- Best Western Plus Panama City Hotel
- Hilton Garden Inn Panama City Airport
- Hotel Indigo Panama City Marina, an IHG Hotel
- Hathaway Inn
- Microtel Inn & Suites by Wyndham Panama City
- Ramada by Wyndham Panama City
- Red Roof Inn Panama City
- Holiday Inn Panama City, an IHG Hotel