Find hotels in Cairo, IL
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check Cairo hotel prices
Tonight |
Tomorrow night |
This weekend |
Next weekend |
Compare 22 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.
Quality Inn Cairo I-57
Quality Inn Cairo I-57
6.6 out of 10, (224)
The price is $80
$89 total
includes taxes & fees
May 28 - May 29
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
6.8 out of 10, (498)
The price is $62
$69 total
includes taxes & fees
Jun 10 - Jun 11
Quality Inn - Sikeston
Quality Inn - Sikeston
6.8 out of 10, (326)
The price is $63
$70 total
includes taxes & fees
Jun 9 - Jun 10
Save an average of 15% on thousands of hotels when you're signed in
Eagle Inn Charleston
Eagle Inn Charleston
6.8 out of 10, (93)
The price is $70
$78 total
includes taxes & fees
May 28 - May 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More cheap stays in Cairo
Super 8 by Wyndham Charleston MO
310 S Story St, Charleston, MO
6.6/10 (497 reviews)
Stay near popular Cairo attractions
Fort Defiance State Park
4/5(14 reviews)
Explore the great outdoors at Fort Defiance State Park, a lovely green space in Cairo. Stroll along the riverfront or experience the area's entertainment venues.
Cairo Travel Info
Number of reviews | 1,140 |
---|---|
Accommodation | 22 hotels |
Highest price | |
Lowest price | |
Why to go | Fort Defiance |
Frequently asked questions
Recent reviews of Cairo hotelsExpedia verified reviews
5/5 Excellent
Our third stay…
"This was our third time booking this home on VRBO. We always enjoy our stay here, and this time was no different. It’s a very cozy home to stay in. We never spend much time here throughout the day since we always come up from Texas to visit family here locally, however we are here overnights. The beds are very comfortable, and it’s very spacious and quiet. They are pet friendly and since we never travel without our dogs, it makes it very nice to book here. We plan to return again next Spring."
A verified traveler from San Antonio, TX stayed at Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Posted 7 days ago
Stay near popular Cairo attractions
- Hotels near Fort Defiance State Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Columbus-Belmont State Park
- Hotels near Henry N Barkhausen Cache River Wetlands Center
- Hotels near Ullin City Hall
- Hotels near Shawnee Community College
- Hotels near Mound City National Cemetery
- Hotels near Ballard Wildlife Management Area
- Hotels near Front Street Studio & Art Gallery
More Accommodation Types in Cairo
Hotels near Cairo Airports
Cairo Hotels by Brand
Other Hotels near Cairo, Illinois
- Hotels in Paducah
- Hotels in Cape Girardeau
- Hotels in Sikeston
- Hotels in Southern Illinois
- Hotels in Anna
- Hotels in Charleston
- Hotels in Southeast Missouri
- Hotels in Miner
- Hotels in Western Kentucky
- Hotels in West Paducah
- Hotels in Scott City
- Hotels in Jonesboro
- Hotels in The South
- Hotels in Dongola
- Hotels in Benton
- Hotels in La Center
- Hotels in Wickliffe
- Hotels in Clinton
- Hotels in East Prairie
- Hotels in Central United States
Expedia's Latest Trends
Hotels
Hotels in GalenaGolf Hotels in MortonHotels in BloomingtonHotels in DecaturHotels in ChampaignHotels in PeoriaHotels in SpringfieldHotels in Mount VernonHotels in AuroraHotels in Tinley ParkHotels in QuincyHotels in RockfordHotels in CarbondaleCheap Hotels in SpringfieldHotels in JolietHotels in EffinghamHotels in MarionHotels in Normal
Flights