Find 5 Star Hotels in Little Italy, CA from $161

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on over 100,000 hotels worldwide as a One Key member.

Search over 2.9 million properties and 550 airlines worldwide.

Compare Little Italy 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Front of property
Pendry San Diego
5.0 star property
9.4 out of 10, Exceptional, (1001)
"Full service hotel, and fantastic location. Accommodating staff, great timing options right in the hotel, as well as ample dining in the gaslamp district."
The price is $293
$380 total
includes taxes & fees
Jun 6 - Jun 7
Pendry San Diego
Exterior
THE US GRANT, a Luxury Collection Hotel, San Diego
5.0 star property
9.0 out of 10, Wonderful, (1002)
"Overall fine property"
The price is $263
$296 total
includes taxes & fees
Jun 6 - Jun 7
THE US GRANT, a Luxury Collection Hotel, San Diego
Exterior
L'Auberge Del Mar
5.0 star property
8.6 out of 10, Excellent, (718)
"Nice property. Great location. Showing wear in many locations but overall a nice hotel."
The price is $387
$494 total
includes taxes & fees
May 27 - May 28
L'Auberge Del Mar
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Outdoor pool, pool umbrellas
The Lodge at Torrey Pines
5.0 star property
9.2 out of 10, Wonderful, (713)
"We were disappointed in the restaurant. We had breakfast at The Grill and enjoyed it. The restaurant not so much. Asking for an additional tip for the cook staff considering the prices was inappropriate. "
The price is $499
$625 total
includes taxes & fees
May 24 - May 25
The Lodge at Torrey Pines
Exterior
Fairmont Grand Del Mar
5.0 star property
9.6 out of 10, Exceptional, (712)
"This was a great family getaway for a birthday celebration. The whole family had a fantastic time, including activities such as horseback riding, trail exploration, archery, and enjoying the kids’ club and all the amenities. It’s a wonderfully relaxing location, and we will definitely be back."
The price is $359
$472 total
includes taxes & fees
Jun 5 - Jun 6
Fairmont Grand Del Mar
2 outdoor pools
Rancho Valencia Resort and Spa
5.0 star property
9.8 out of 10, Exceptional, (124)
"Nice place, a little noisy as we were near the pool"
The price is $771
$895 total
includes taxes & fees
May 28 - May 29
Rancho Valencia Resort and Spa

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Little Italy.
Sheraton San Diego Hotel and Marina

Sheraton San Diego Hotel and Marina

1380 Harbor Island Dr, San Diego, CA
The price is $189 per night from May 27 to May 28
$189
$242 total
includes taxes & fees
May 27 - May 28
7.6/10 Good! (2,239 reviews)
Still don't see what you're looking for?
See all properties in Little Italy.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

You enjoy the finer things in life, both at home and on vacation. Treat yourself on your upcoming getaway. There's no reason to delay a getaway to Little Italy any longer. You'll join the multitudes of vacationers who have made Little Italy so fashionable in the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Reserve one of our 5-star hotels in Little Italy and indulge in the finer things in life for a while.

Book the Best Little Italy 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. Top-notch service, delicious meals, and personalized service are all at your fingertips. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A mud wrap treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.

You won't sleep and order room service the entire time, though. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Little Italy are the perfect place to relax after an exciting day.

Your Getaway Starts Today

The results are in, and Little Italy 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Choose one of the 5-star hotels in Little Italy today and settle down in luxe surroundings when you're ready.

Frequently asked questions

What are the best 5-star hotels in Little Italy?
Relax in the lap of luxury at THE US GRANT, a Luxury Collection Hotel, San Diego. Favored by our customers for its elevated standard of comfort and grandeur, this 5-star hotel located around the San Diego Coast neighborhood of Little Italy is a cut above the rest.
How much does it cost to stay in a 5-star hotel in Little Italy?
How much you pay for a 5-star hotel in Little Italy can vary according to when you want to travel and how long you plan to stay, among a number of factors. Use our price per night filter and other search tools to score the best deal on a high-end stay.

  • Search for the lowest price per night from $161

What makes a hotel 5 stars in Little Italy?
In Little Italy, a hotel is required to offer a specific number of upscale amenities to be designated 5 stars. These may include gourmet restaurants, on-site gyms, saunas and spas, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary standard of service. You’ll enjoy things like nightly turn-down services, in-room massages and concierge services. Some may also offer additional touches like a welcome gift.
Are there any 5-star all-inclusive resorts in Little Italy?
Expedia’s filters are the best way to narrow down what you’re looking for. Select “5-star” and “All inclusive” to show the finest resorts in Little Italy where your room, meals, entertainment and activities are included in the price. At these getaways, your vacation is pure indulgence from the moment you enter the lobby.
What are the top 5-star spa hotels in Little Italy?
Get comfortable at Pendry San Diego and relax, indulge and unwind. It’s one of the finest 5-star spa properties around Little Italy offering revitalizing treatments such as facials, massages and more.
Are there any 5-star vacation rentals in Little Italy?
Although you won’t find any 5-star vacation rentals in Little Italy on our site, we have a range of stays that promise a fantastic getaway. Discover one that suits your needs by checking out our vacation rentals in Little Italy.