$224 Cheap Flights from New Orleans (MSY) to Florence (FLO)

Bundle Your Flight + Hotel & Save!

Featured airlines

Top nine airline logos for desktop

    Plan, book, fly with confidence
  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash

Cheap Flights from New Orleans to Florence (MSY-FLO)

Prices were available within the past 7 days and start at $224 for one-way flights and $492 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
Flights from New Orleans (MSY) to Florence (FLO)
Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
Florence Regional
Airlines serving
American Airlines
Roundtrip price
$491
Distance
680 mi

New Orleans to Florence Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from New Orleans to Florence offer the perfect respite. Not only does exploring Florence provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from New Orleans to Florence may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Florence are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to Florence more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Florence is $224 now!

Frequently asked questions

Is it cheaper to buy a plane ticket from Louis Armstrong New Orleans Intl. Airport to Florence Regional Airport (FLO) last minute?
Booking your flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Florence Regional Airport (FLO) last minute could save you cash if you happen to find an amazing deal. However, tickets don’t typically get cheaper closer to the departure date. If you wait, flights could also be booked up or the best seats taken (don’t get stuck in the middle!). If you don’t want to risk it, book well ahead of your departure date. Keep in mind that some of the best deals can be found up to a year in advance. If your preferred airline hasn’t released its fares yet, check back regularly as offers are constantly updated on Expedia.
What airports do you fly into for Florence from New Orleans?
With Florence Regional Airport (FLO), Myrtle Beach Intl. Airport (MYR) and Hartsville Regional Airport (HVS) to pick from, making your way from New Orleans to Florence is a cinch. The city’s major gateway, Florence Regional Airport (FLO), is around 2 mi east of the downtown area. Along with the price of fares, consider things like public transportation options from the airport and the distance to your hotel when deciding where to touch down. Get your Florence vacation off to a superb start by exploring Florence Civic Center and Magnolia Mall.
Can I change the date of my flight from MSY to Florence Regional Airport?
Quickly and easily make changes to your Louis Armstrong New Orleans Intl. Airport (MSY) to Florence Regional Airport (FLO) trip by logging in to the Expedia Trips portal. Before making any amendments, browse the rules and restrictions in your itinerary to find out what the carrier will allow you to do and what charges may apply. Some airlines charge a change fee per person, plus any difference in ticket prices. However, if you booked in the last 24 hours, you may be able to cancel for free and arrange new flights. You can also browse our Customer Service portal to find the answers to your questions and to chat with our Virtual Agent.
*Available to One Key members.