$69 Cheap Flights from Chicago (MDW) to Knoxville (TYS)

Bundle Your Flight + Hotel & Save!

Featured airlines

Top nine airline logos for desktop

    Plan, book, fly with confidence
  • trending down icon
    Be in the know
    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon
    Book smarter
    Save up to 30% on select hotels after you book a flight*
  • one key icon
    Earn twice
    Earn your airline miles on top of our OneKeyCash

Cheap Flights from Chicago to Knoxville (MDW-TYS)

Prices were available within the past 7 days and start at $69 for one-way flights and $126 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Flights from Chicago (MDW) to Knoxville (TYS)
Origin airport
Midway Intl.
Destination airport
McGhee Tyson
Airlines serving
Delta, Frontier Airlines
Roundtrip price
$126
Distance
459 mi
Average flight time
2 hours 28 mins

Chicago to Knoxville Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from Chicago to Knoxville offer the perfect respite. Not only does exploring Knoxville provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from Chicago to Knoxville may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Knoxville are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to Knoxville more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Knoxville is $69 now!

Frequently asked questions

How much is a one-way flight from MDW to McGhee Tyson Airport (TYS)?
Get set to score a great deal, because one-way Chicago flights to Knoxville start from just $73. This is based on the cheapest fare found on Expedia for this route departing within the next three months. This airfare is for an Frontier Airlines flight, taking off from Chicago Airport on May 30 2024 and touching down at McGhee Tyson Airport (TYS). The price was updated on May 21 2024 and has not changed since.
Is it cheaper to buy a plane ticket from Midway Intl. Airport (MDW) to TYS last minute?
When it’s time to book your flights, it’s always better to be prepared. While you could pick up a last-minute deal on a Midway Intl. Airport (MDW) to McGhee Tyson Airport (TYS) flight, prices usually don’t get cheaper as the departure date nears. Based on flight pricing and demand studies in 2022, we have found that the sweet spot to book a domestic flight is between 28 – 35 days in advance. For international journeys it’s between three and four months.
What is the cheapest airline flying from Midway Intl. Airport (MDW) to Knoxville Airport in the next 90 days?
With fares from $73 for a flight from Chicago to Knoxville, Frontier Airlines is the cheapest airline found on Expedia. This price is based on airfares found on Expedia departing within the next 90 days and was last updated on May 21 2024 and has not changed since. The flight takes off from Midway Airport on May 30 2024 and lands at Knoxville Airport.
What's the cheapest price for a flight from Midway Intl. Airport (MDW) to Knoxville Airport next month?
You can pick up a flight from Chicago to Knoxville for just $73. This is the cheapest price for this journey with a departure date in the next month. It’s an Frontier Airlines flight heading off from Chicago Airport on May 30 2024 and touching down at Knoxville Airport. The pricing info was correct as of May 21 2024 and has not changed since. It was found after searching all available flights on Expedia within the next 30 days.
What airports do you fly into for Knoxville from Chicago?
With McGhee Tyson Airport (TYS), Gatlinburg, TN (GKT-Gatlinburg - Pigeon Forge) and Morristown, TN (MOR-Moore-Murrell) to select from, traveling from Chicago to Knoxville is easy. The city’s busiest terminal, McGhee Tyson Airport (TYS), is about 12 mi south of the downtown area. Along with ticket prices, consider things like transportation options from the airport and the distance to your hotel before deciding where you’ll get off the plane. Get your Knoxville adventure off to an awesome start by exploring Ijams Nature Center and Knoxville Zoological Gardens.
Can I change the date of my flight from Midway Airport to Knoxville Airport?
Sometimes life gets in the way of plans, so Expedia is here to help make amending your flight as easy as possible. First, find your Midway Intl. Airport (MDW) to Knoxville Airport itinerary through the Expedia Trips portal and read the fare rules and conditions about what changes are allowed. If you booked your ticket in the last 24 hours, some airlines allow you to cancel at no cost and book new flights. If you bought your fare more than 24 hours ago, contact us through our Customer Service portal so we can help you further.
Chicago nearby Airports
*Available to One Key members.