Photo by Jessica Richter
Find hotels in Southeast Missouri, MO from $57
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Compare 565 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
8.8 out of 10, Excellent, (1004)
The price is $66
$75 total
includes taxes & fees
Jul 8 - Jul 9
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1002)
The price is $112
$127 total
includes taxes & fees
Jun 16 - Jun 17
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
9.0 out of 10, Wonderful, (1012)
The price is $67
$76 total
includes taxes & fees
Jun 13 - Jun 14
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Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MO
8.0 out of 10, Very Good, (634)
The price is $57
$65 total
includes taxes & fees
Jun 23 - Jun 24
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
9.0 out of 10, Wonderful, (1005)
The price is $63
$71 total
includes taxes & fees
Jun 13 - Jun 14
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
9.6 out of 10, Exceptional, (1013)
The price is $117
$133 total
includes taxes & fees
Jun 16 - Jun 17
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
8.0 out of 10, Very Good, (1006)
The price is $75
$80 total
includes taxes & fees
Jun 21 - Jun 22
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
8.8 out of 10, Excellent, (385)
The price is $88
$95 total
includes taxes & fees
Jun 9 - Jun 10
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
9.6 out of 10, Exceptional, (344)
The price is $118
$134 total
includes taxes & fees
Jun 16 - Jun 17
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1008)
The price is $99
$112 total
includes taxes & fees
Jun 16 - Jun 17
Travel Inn & Suites
Travel Inn & Suites
8.4 out of 10, Very Good, (527)
The price is $60
$69 total
includes taxes & fees
Jun 16 - Jun 17
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
8.2 out of 10, Very Good, (633)
The price is $88
$104 total
includes taxes & fees
Jun 16 - Jun 17
Baymont by Wyndham Sullivan
Baymont by Wyndham Sullivan
7.8 out of 10, Good, (1000)
The price is $98
$107 total
includes taxes & fees
Jun 30 - Jul 1
The Farmstead Hotel
The Farmstead Hotel
8.8 out of 10, Excellent, (197)
The price is $105
$119 total
includes taxes & fees
Jun 9 - Jun 10
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (627)
The price is $114
$128 total
includes taxes & fees
Jun 16 - Jun 17
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
9.4 out of 10, Exceptional, (1010)
The price is $94
$108 total
includes taxes & fees
Jun 16 - Jun 17
Super 8 by Wyndham Farmington
Super 8 by Wyndham Farmington
8.0 out of 10, Very Good, (435)
The price is $57
$65 total
includes taxes & fees
Jun 9 - Jun 10
Quality Inn
Quality Inn
7.0 out of 10, Good, (471)
The price is $68
$77 total
includes taxes & fees
Jun 9 - Jun 10
Best Western Plus Sikeston
Best Western Plus Sikeston
8.4 out of 10, Very Good, (1010)
The price is $98
$111 total
includes taxes & fees
Jun 10 - Jun 11
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More cheap stays in Southeast Missouri
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
The price is $69 per night from Jun 16 to Jun 17
$69
$78 total
includes taxes & fees
Jun 16 - Jun 17
7/10 Good! (1,008 reviews)
Stay near popular Southeast Missouri attractions
Meramec Caverns
5/5(21 reviews)
Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the coffeehouses.
Recent reviews of Southeast Missouri hotelsExpedia verified reviews
5/5 Excellent
"Very friendly, professional and personable staff that we interacted with including front desk, house keeping and and older gentleman wearing a blue uniform."
A verified traveler from Independence stayed at Pear Tree Inn Cape Girardeau Near the Medical Center
Posted 1 day ago
Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
- Johnson's Shut-ins State Park
- Elephant Rocks State Park
- Mark Twain National Forest
- Echo Bluff State Park
- Current River
- Ozark National Scenic Riverways
- Southeast Missouri State University
- Lake Wappapello
- Big Spring
- Alley Spring & Mill
- Century Casino Caruthersville
- Isle Casino Cape Girardeau
- Current River State Park
- Clearwater Lake
- Taum Sauk Mountain State Park
- K Bridge Recreation Area
- Rocky Falls
- Akers Ferry
- Black River Coliseum
- Bonne Terre Mine
More Hotel Options in Southeast Missouri
- Business Hotels (50)
- Casinos (13)
- Cheap Hotels (23)
- Family Hotels (60)
- Golf Hotels (28)
- Historic Hotels (10)
- Hotel Wedding Venues (16)
- Hotels & Resorts for Couples (17)
- Hotels with Air Conditioning (71)
- Hotels with Balconies (5)
- Hotels with Bars (19)
- Hotels with Connecting Rooms (24)
- Hotels with Free Breakfast (53)
- Hotels with Free Parking (65)
- Hotels with Free Wifi (64)
- Hotels with Hot Tubs (22)
- Hotels with Laundry Facilities (47)
- Hotels with Restaurants (67)
- Hotels with Suites (9)
- Hotels with Tennis Courts (5)
- Hotels with a Gym (35)
- Hotels with a Pool (45)
- Hotels with a View (5)
- Hotels with an Indoor Pool (26)
- Hotels with an Outdoor Pool (43)
- Hotels with smoking rooms (9)
- Luxury Hotels (12)
- Non-Smoking Hotels (33)
- Pet-friendly Hotels (48)
- Resorts & Hotels with Spas (14)
- Romantic Hotels (5)
- Winery Hotels (7)
More Accommodation Types in Southeast Missouri
Hotels near Southeast Missouri Airports
Southeast Missouri Hotels by Brand
Other Hotels near Southeast Missouri, Missouri
- Chesterfield Hotels
- Cape Girardeau Hotels
- Carbondale Hotels
- Poplar Bluff Hotels
- Sikeston Hotels
- Hardy Hotels
- Van Buren Hotels
- Eminence Hotels
- East St. Louis Hotels
- Ozarks Hotels
- Eureka Hotels
- Farmington Hotels
- Fenton Hotels
- Ste Genevieve Hotels
- Arnold Hotels
- Kirkwood Hotels
- West Plains Hotels
- Sullivan Hotels
- Wildwood Hotels
- Southern Illinois Hotels
More Popular Hotels in Missouri
- Super 8 by Wyndham Farmington
- Silo Farm Haus- located in the heart of wine country!
- Drury Inn & Suites Cape Girardeau
- Pear Tree Inn Sikeston
- Courtyard by Marriott Cape Girardeau Downtown
- Best Western Plus Sikeston
- Candlewood Suites Cape Girardeau, an IHG Hotel
- Comfort Inn Festus - St Louis South
- New Orleans Inn Portageville
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Town House Inn
- Quality Inn
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