Find Casino Hotels & Resorts in Sikeston, MO from $63

Tourists speak highly of the family-friendly activities, shopping, and local cuisine.

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel is a hotel featuring free breakfast and free WiFi, and it’s a top choice near the casinos.

You won’t need a stroke of luck to find something that suits with one of Expedia’s 13 casino hotels in Sikeston.

You might spend a lot of your vacation inside, but if you want to see more of the area, looking at local weather trends is a good idea. The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.

If you’re interested in local cultural spots, you can check out Sikeston Depot Museum and Front Street Studio & Art Gallery. Nature enthusiasts will appreciate the riverfront, and places to get outdoors include Mississippi River. If you’re looking for more to see and do, you can add The Book Bug and Central Park to your list.

Here are some transportation options in Sikeston: You can arrange a flight to the nearest airport, which is Cairo, IL (CIR-Cairo Regional), 23.8 mi (38.3 km) from the city center. If you’d like to explore around the area, you may want a rental car for your journey.