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Discover 388 Downtown Rochester hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, (608)
"Clean, friendly staff, and great location."
The price is $108
$126 total
includes taxes & fees
Jul 4 - Jul 5
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Kahler Inn and Suites - Mayo Clinic Area
Aerial view
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, (1219)
"Liked how close it was to Mayo. The AC was very loud."
The price is $108
$125 total
includes taxes & fees
Jun 28 - Jun 29
Kahler Inn and Suites - Mayo Clinic Area
Kahler Grand Hotel
Indoor pool
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very Good, (1016)
"Extremely close to Mayo Clinic Excellent staff"
The price is $139
$161 total
includes taxes & fees
Jun 27 - Jun 28
Kahler Grand Hotel
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Hyatt House Rochester/Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, (564)
"Only problems: when I checked in the person in front of me was given 2 bottles of water. I did not receive any. When I asked, I was told I was not entitled to this because I booked through a third party! Also, the tv lost its signal several times."
The price is $107
$123 total
includes taxes & fees
Jun 29 - Jun 30
Hyatt House Rochester/Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
7.8 out of 10, Good, (1006)
" Adequate for a short stay, was not in need of many amenities. Clean and comfortable."
The price is $89
$103 total
includes taxes & fees
Jun 30 - Jul 1
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, (546)
"Super close to Mayo Clinic"
The price is $117
$138 total
includes taxes & fees
Jul 1 - Jul 2
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Exterior
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1005)
"Pond next door, walking paths, shuttle to hospital and many things close by"
The price is $97
$112 total
includes taxes & fees
Jun 16 - Jun 17
Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
In-room safe, desk, iron/ironing board, free cribs/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
8.0 out of 10, Very Good, (1008)
"The room was small, but okay for a single person. The bed was okay, it was clean. Loved the bench above the air conditioner/heater. The breakfast was standard cold and hot items, but not much for sitting, so you may need to eat in your room. The down fall was I could hear a TV going in the next room and in the other room, hear a phone alarm going off."
The price is $67
$77 total
includes taxes & fees
Jun 27 - Jun 28
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Hampton Inn Rochester-South
Terrace/patio
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, (1011)
"Staff is awesome!! Room smelled wonderful but it is a weird layout. Only negative was the bed. Felt like the springs were eating me all night. "
The price is $92
$105 total
includes taxes & fees
Jul 5 - Jul 6
Hampton Inn Rochester-South
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Blackout drapes, soundproofing, iron/ironing board, free WiFi
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
8.2 out of 10, Very Good, (396)
"The room was spacious and comfortable. The breakfast was excellent. It is an older building, so there were fewer electrical outlets but mostly this was not a serious problem."
The price is $88
$102 total
includes taxes & fees
Jun 12 - Jun 13
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Residence Inn by Marriott Rochester Mayo Clinic Area South
BBQ/picnic area
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.4 out of 10, Exceptional, (87)
"Wonderful rooms and accommodations. "
The price is $114
$131 total
includes taxes & fees
Jun 22 - Jun 23
Residence Inn by Marriott Rochester Mayo Clinic Area South
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, (620)
"Great place to stay. Accessible to everything."
The price is $101
$116 total
includes taxes & fees
Jul 5 - Jul 6
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Free daily buffet breakfast
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.8 out of 10, Exceptional, (284)
"Coffee shop on the property was very convenient."
The price is $118
$136 total
includes taxes & fees
Jun 14 - Jun 15
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
2.5 star property
8.8 out of 10, Excellent, (615)
"Everything was very well done, all of the staff very friendlyand eager to please.. Breakfast was quite delicious. "
The price is $102
$118 total
includes taxes & fees
Jul 5 - Jul 6
Holiday Inn Express & Suites Rochester – Mayo Clinic Area, an IHG Hotel
Home2 Suites by Hilton Rochester Mayo Clinic Area
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, (629)
"It’s close to the shopping center, Mayo Clinic and restaurants. The rooms are spacious. "
The price is $127
$146 total
includes taxes & fees
Jul 7 - Jul 8
Home2 Suites by Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
Lobby
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6 out of 10, Exceptional, (339)
"Beautiful, clean property! "
The price is $169
$195 total
includes taxes & fees
Jul 3 - Jul 4
Hilton Rochester Mayo Clinic Area
Quality Inn near Medical Center
Indoor spa tub
Quality Inn near Medical Center
2.5 star property
8.0 out of 10, Very Good, (503)
"Very quiet and close to Mayo. Nice pool and hottub. Full breakfast"
The price is $63
$72 total
includes taxes & fees
Jul 3 - Jul 4
Quality Inn near Medical Center
Brentwood Inn & Suites
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites
2.5 star property
8.6 out of 10, Excellent, (1002)
"We spent several days at the Brentwood for medical appointments. The staff was very friendly, our room was very clean and we enjoyed our stay there very much. They provided a simple continental breakfast which was fine for our needs. When we needed to extend our stay, it was not a problem and we even got a lower rate. Prices were very reasonable."
The price is $109
$125 total
includes taxes & fees
Jun 21 - Jun 22
Brentwood Inn & Suites
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
8.2 out of 10, Very Good, (1011)
"Great location with the best staff & dining!!!!!!"
The price is $120
$139 total
includes taxes & fees
Jun 28 - Jun 29
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Aspen Select
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Aspen Select
3.5 star property
8.6 out of 10, Excellent, (1004)
"I had family in the hospital and it was very close to Saint Francis hospital. "
The price is $125
$159 total
includes taxes & fees
Jun 8 - Jun 9
Aspen Select
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Downtown Rochester

Hotels in top Rochester neighborhoods Learn more about Downtown Rochester
Rochester showing skyline and a city

Historic Southwest

1 out of top 10 points of interest in this area
4/5(34 area reviews)

Historic Southwest might not have many top sights, but Mayo Civic Center and Apache Mall are two attractions nearby that you can check out.

Find hotels in Historic Southwest

Downtown Rochester Travel Info

Number of reviews
14,411
Location
Rochester, United States of America
Similar neighborhoods
Kutzky Park, East Side Pioneers and Historic Southwest
Accommodation
388 hotels
Known landmarks
Rochester Civic Theater, Minnesota Childrens Museum and Cascade Lake Beach
Hotels with golf
Kahler Inn and Suites - Mayo Clinic Area, Kahler Grand Hotel and Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Known for
Bars and pubs, history and culture
Lowest price
$63
Highest price
$169

Frequently asked questions

What's it like in Downtown Rochester?

You'll be sure to have fun visiting Rochester's Downtown Rochester neighborhood. Are you looking for Downtown Rochester travel tips? Be sure to check out Mayo Civic Center and Rochester Civic Theater while you're in the neighborhood.

What's a favorite place to stay in Downtown Rochester?

Based on Expedia customer reviews, Hilton Rochester Mayo Clinic Area is the highest ranked property in Downtown Rochester. This hotel is a short 3-minute walk from Mayo Civic Center, and it offers a full-service spa and 2 restaurants. Other favorite options in the area include TownePlace Suites by Marriott Rochester Mayo Clinic Area and The Towers At Kahler Grand Hotel.

How many hotels will I be able to find in the Downtown Rochester area?

Expedia has 22 hotels and other accommodations in Downtown Rochester to choose from, making this an ideal home base for exploring the greater Rochester area.

If I need to cancel my hotel reservation in Downtown Rochester, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Downtown Rochester.

Where can I learn more about changing or cancelling my trip to Downtown Rochester?

For additional details about rescheduling or cancelling your trip to Downtown Rochester, click here.

What is there to do in this Rochester neighborhood?

Mayo Civic Center, Rochester Civic Theater, and Mayo Park are just a few attractions to check out in Downtown Rochester. Shops University Square and Rochester Art Center are also a couple of places to visit in the neighborhood. A few places to visit in the area around Downtown Rochester include Soldiers Field Veterans Memorial, Soldiers Field Golf Course, and Silver Lake Park. Plummer House and Minnesota Children's Museum are also worth a visit when you're out sightseeing in Rochester.

Recent reviews of Downtown Rochester hotels

Brentwood Inn & Suites

Brentwood Inn & Suites

5/5 Excellent
Very pleased with our stay
"We spent several days at the Brentwood for medical appointments. The staff was very friendly, our room was very clean and we enjoyed our stay there very much. They provided a simple continental breakfast which was fine for our needs. When we needed to extend our stay, it was not a problem and we even got a lower rate. Prices were very reasonable."
A verified traveler stayed at Brentwood Inn & Suites
Posted 2 days ago
Brentwood Inn & Suites