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Discover 4,419 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Rosarito Beach Hotel
3 outdoor pools
Rosarito Beach Hotel
3.0 star property
7.8 out of 10, Good, (1014)
"Nice place to stay! Thank you!"
The price is $159
$180 total
includes taxes & fees
Jul 3 - Jul 4
Rosarito Beach Hotel
Grand Hotel Tijuana
Outdoor pool
Grand Hotel Tijuana
3.5 star property
8.8 out of 10, Excellent, (2500)
"Outstanding hotel, staff and service. "
The price is $101
$116 total
includes taxes & fees
Jun 16 - Jun 17
Grand Hotel Tijuana
Best Western Plus Marina Gateway Hotel
Exterior
Best Western Plus Marina Gateway Hotel
3.5 star property
9.0 out of 10, Wonderful, (2566)
"Grateful to have slept in a nice hotel "
The price is $169
$190 total
includes taxes & fees
Jun 9 - Jun 10
Best Western Plus Marina Gateway Hotel
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Loews Coronado Bay Resort
Exterior
Loews Coronado Bay Resort
4.0 star property
8.6 out of 10, Excellent, (1054)
"Our second time staying here for our annual Memorial Day girls trip! Beautiful property, a true resort experience. Just wish was a little closer to center of town especially since Coronado Beach shuttle not running until July this year!!"
The price is $249
$323 total
includes taxes & fees
Jun 9 - Jun 10
Loews Coronado Bay Resort
The Rambler Motel
View from room
The Rambler Motel
3.0 star property
9.0 out of 10, Wonderful, (1751)
"It’s good"
The price is $129
$149 total
includes taxes & fees
Jun 16 - Jun 17
The Rambler Motel
SureStay Hotel by Best Western Chula Vista San Diego Bay
Outdoor pool
SureStay Hotel by Best Western Chula Vista San Diego Bay
3.0 star property
7.2 out of 10, Good, (1109)
"The property is as per the description great location very clean free buffet breakfast. "
The price is $99
$109 total
includes taxes & fees
Jun 9 - Jun 10
SureStay Hotel by Best Western Chula Vista San Diego Bay
Hotel Festival Plaza Playas Rosarito
Standard Room, 1 King Bed | Individually decorated, bed sheets
Hotel Festival Plaza Playas Rosarito
3.0 star property
7.0 out of 10, Good, (1213)
"Loved that its walking distance to the beach, no need to drive anywhere. The lobby is nice looking, but booked 3 rooms and they were all very outdated and old, the window area feels like its gonna break if you lean on it of how old it is."
The price is $74
$83 total
includes taxes & fees
Jun 9 - Jun 10
Hotel Festival Plaza Playas Rosarito
Hotel Palmeras Chula Vista
Exterior
Hotel Palmeras Chula Vista
2.0 star property
7.0 out of 10, Good, (1600)
"Loved the place. "
The price is $98
$108 total
includes taxes & fees
Jun 19 - Jun 20
Hotel Palmeras Chula Vista
Hotel Ticuán
Property entrance
Hotel Ticuán
3.5 star property
9.0 out of 10, Wonderful, (1728)
"ALL is excellent"
The price is $81
$94 total
includes taxes & fees
Jun 20 - Jun 21
Hotel Ticuán
MISION 11
Front of property
MISION 11
3.0 star property
7.8 out of 10, Good, (405)
"Nice play to stay for a night but probably not for an extended stay. Rooms are really small. Make sure to ask for a room with windows, most rooms don’t have windows except for a certain side of the hotel building. The hot water in our room didn’t work well but our AC did. There’s a restaurant next door so it’s good to grab something to eat. Can’t really complain for the price of the room."
The price is $48
$58 total
includes taxes & fees
Jun 9 - Jun 10
MISION 11
Hotel Grand One Plaza
Terrace/patio
Hotel Grand One Plaza
3.0 star property
8.4 out of 10, Very Good, (639)
"friendly English-speaking staff"
The price is $60
$74 total
includes taxes & fees
Jun 13 - Jun 14
Hotel Grand One Plaza
Hotel Pueblo Amigo Plaza & Casino
Down comforters, in-room safe, desk, blackout drapes
Hotel Pueblo Amigo Plaza & Casino
3.5 star property
9.2 out of 10, Wonderful, (1010)
"Safe"
The price is $146
$165 total
includes taxes & fees
Jun 27 - Jun 28
Hotel Pueblo Amigo Plaza & Casino
Hotel Corona Plaza
Superior Double Room | View from room
Hotel Corona Plaza
3.0 star property
6.6 out of 10, (1418)
"It was a 5 night stay, the first night there were a lot of drainage issues. We switched rooms on the second night and there we had no issues whatsoever. Everything was fine. Breakfast was good "
The price is $57
$64 total
includes taxes & fees
Jun 23 - Jun 24
Hotel Corona Plaza
Real Inn Tijuana by Camino Real Hotels
Bar (on property)
Real Inn Tijuana by Camino Real Hotels
4.5 star property
8.4 out of 10, Very Good, (1513)
"The staff was pleasant even with a late check in time and very informative."
The price is $110
$124 total
includes taxes & fees
Jun 16 - Jun 17
Real Inn Tijuana by Camino Real Hotels
La Quinta Inn by Wyndham San Diego Chula Vista
Exterior
La Quinta Inn by Wyndham San Diego Chula Vista
2.5 star property
8.4 out of 10, Very Good, (1018)
"Quiet very helpful front desk "
The price is $116
$128 total
includes taxes & fees
Jun 16 - Jun 17
La Quinta Inn by Wyndham San Diego Chula Vista
Ibis Tijuana Zona Rio
Reception
Ibis Tijuana Zona Rio
3.0 star property
8.0 out of 10, Very Good, (1157)
"This place was amazing, walking distance to many shops. Hotel was super pretty and breakfast was amazing all really good tasting. "
The price is $80
$91 total
includes taxes & fees
Jun 22 - Jun 23
Ibis Tijuana Zona Rio
Motel 6 Chula Vista, CA - San Diego
Lobby
Motel 6 Chula Vista, CA - San Diego
2.0 star property
6.0 out of 10, (2089)
"Nice place, front desk staff are accommodating "
The price is $78
$86 total
includes taxes & fees
Jun 9 - Jun 10
Motel 6 Chula Vista, CA - San Diego
Hotel Castillos del Mar
2 bars/lounges, beach bar
Hotel Castillos del Mar
3.0 star property
6.6 out of 10, (1010)
"Everything was just about as expected from the listing. Staff was accommodating and kind. Only thing that wasn’t awesome was the private event going on with loud music until 3am making it extremely difficult to get any rest. Shout out to the security guard Margarito for helping us get a trustworthy taxi! "
The price is $76
$85 total
includes taxes & fees
Jun 16 - Jun 17
Hotel Castillos del Mar
Best Western Chula Vista/Otay Valley Hotel
Lobby
Best Western Chula Vista/Otay Valley Hotel
2.5 star property
7.4 out of 10, Good, (1111)
"It was very close to where I needed to be. Free breakfast was great. Rooms are remodeled with a very modern look."
The price is $135
$149 total
includes taxes & fees
Jun 16 - Jun 17
Best Western Chula Vista/Otay Valley Hotel
Avid Hotels Tijuana Otay, an IHG Hotel
Premium bedding, pillowtop beds, in-room safe, desk
Avid Hotels Tijuana Otay, an IHG Hotel
3.0 star property
9.6 out of 10, Exceptional, (752)
"El personal es muy amable."
The price is $80
$90 total
includes taxes & fees
Jul 7 - Jul 8
Avid Hotels Tijuana Otay, an IHG Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Otay Mesa

Hotels in top San Diego neighborhoods Learn more about Otay Mesa
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

From historic streets, waterfront parks and baseball, to performing arts venues, nightlife zones and art and maritime museums, this is the cultural hub of San Diego.

Find hotels in Downtown San Diego

Otay Mesa Travel Info

Number of reviews
26,621
Location
San Diego, United States of America
Similar neighborhoods
Central San Diego, Mission Valley West and Midway District
Accommodation
4,419 hotels
Hotels with connecting rooms
Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel and Quality Suites San Diego Otay Mesa
Lowest price
$48
Highest price
$249

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Quality Suites San Diego Otay Mesa is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel.

How many hotels will I be able to find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodations, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

Recent reviews of Otay Mesa hotels

Bahia Resort Hotel

Bahia Resort Hotel

5/5 Excellent
"The staff is so accommodating and welcoming. "
A verified traveler stayed at Bahia Resort Hotel
Posted 21 hours ago
Bahia Resort Hotel