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Compare 42 Vacation Homes in Cape Girardeau with updated reviews, rates, and availability.

Country, hideaway cabin close to town, 15 minutes from wineries
10.0 out of 10, Exceptional, (4)
"Property was great!"
Country, hideaway cabin close to town, 15 minutes from wineries
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (114)
"The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!"
The price is $150
$244 total
includes taxes & fees
Jun 7 - Jun 8
Serenity South -- Gardens, River-Views, and Refreshing Space
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
10.0 out of 10, Exceptional, (80)
"Very quite and peaceful Exactly what I wanted!"
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
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Notting Hill Cottage
9.6 out of 10, Exceptional, (277)
"Excellent location for hiking, exploring the wineries, or just getting away. The hot tub after a long day of hiking in the Shawnee was definitely a plus."
Notting Hill Cottage
Charming 2-Story- C.1847 - River Views - Fast Wifi
9.6 out of 10, Exceptional, (10)
"Cape Girardeau is about the halfway point for us (Wisconsin) and friends from Mississippi. This VRBO is ideally located within walking distance to plenty of restaurants, shops and bars. Property is very clean, has the basics and communication with the owner was super easy. The saloon-style doors for the downstairs bathroom were a little unexpected, but we made it work. We enjoyed our stay and would recommended this property for a long weekend."
Charming 2-Story- C.1847 - River Views - Fast Wifi
Quaint, Beautiful Home next to SEMO and Hospital
9.8 out of 10, Exceptional, (19)
"Clean, quiet and close to what we needed. Great overall experience"
Quaint, Beautiful Home next to SEMO and Hospital
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
9.8 out of 10, Exceptional, (127)
"This was a great location for: biking, kayaking and hiking, and wineries. The kitchen very handy for our needs. Lots of space. Hot tub was nice too."
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
Wine Trail, Cozy Cabin plus hot tub
10.0 out of 10, Exceptional, (72)
"Very clean and comfortable. Close to many wineries. Great sunset view from the hot tub. Quiet setting. Had a nice relaxing weekend. Would book again.❤️"
Wine Trail, Cozy Cabin plus hot tub
* On the Wine Trail * Hot Tub * Wi-Fi *
9.8 out of 10, Exceptional, (203)
"This lovely little place was perfect for my two college-aged children and me to decompress, hike, soak, eat and laugh. Great experience!"
* On the Wine Trail * Hot Tub * Wi-Fi *
On the Wine Trail - Daily Deer Viewing - Wonderful Views - Wi-fi - Rural
10.0 out of 10, Exceptional, (105)
"Very clean and comfortable"
On the Wine Trail - Daily Deer Viewing - Wonderful Views - Wi-fi - Rural
Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
10.0 out of 10, Exceptional, (4)
"The property was just what we needed for several families getting together. Thank you!"
Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
StarView Vineyards | Winery Retreat
10.0 out of 10, Exceptional, (29)
"This was a return trip for friends of 40+ years. Everything was the exact same: bright, clean, and airy. The kitchen has anything you could need to cook a meal (we made two dinners, the second bbq-ing steaks on the grill). The bathrooms are well-stocked and clean. We love this place. So serene. Hope to return in one year, God willing."
StarView Vineyards | Winery Retreat
Serene Private Retreat Close to Shawnee National Forest
The price is $190
$449 total
includes taxes & fees
Jun 13 - Jun 14
Serene Private Retreat Close to Shawnee National Forest
Beautiful Cabin Retreat
8.2 out of 10, Very Good, (39)
"Host had the cabin very clean. New leather couch & recliner. Mattress was extremely comfortable. Washer & Dryer were excellent. Another Rental house near, long-term renters were very quiet. Internet not very good in the Illinois woods. Closed cabin has a musty smell from humidity in the woods. Host had an automatic air freshener going to help with air quality."
The price is $120
$192 total
includes taxes & fees
Jun 7 - Jun 8
Beautiful Cabin Retreat
Charming 3-bedroom house in East Cape, IL with AC, WiFi, privacy fence, TV.
8.8 out of 10, Excellent, (3)
"We were traveling in for our daughter’s college graduation and found this rental to be ideal! The host has the home decorated nicely to make you feel at home. The home is supplied with anything and everything you would need for your stay. Having the fenced in backyard was perfect for our pup to run and the neighborhood is fairly quiet. Thank you!"
The price is $168
$231 total
includes taxes & fees
Jun 17 - Jun 18
Charming 3-bedroom house in East Cape, IL with AC, WiFi, privacy fence, TV.
Little Blue Cottage on Spanish
8.8 out of 10, Excellent, (32)
"We stayed here to visit our two children going to SEMO. Everything about the place was perfect for a couple. The place was cute and the location was perfect"
The price is $90
$110 total
includes taxes & fees
Jun 9 - Jun 10
Little Blue Cottage on Spanish
Victorian home brought back to life on the Shawnee Hills wine trail.
10.0 out of 10, Exceptional, (6)
"We were lucky enough to be able to book this beautiful restored home on the weekend of the eclipse. It's spacious—each of us had our own room—and quaint. Everywhere you turned, the details take you back to the turn of last century. We might have liked to have a stove, but the microwave and hot plate are sufficient. Plus there's an outdoor grill (Warning: we set off the fire alarm while grilling; be sure the house is closed up if you BBQ!). Plenty of small wineries and hiking in the region, and a...
Victorian home brought back to life on the Shawnee Hills wine trail.
Walk to Wineries - Quaint Village - Grill - Patio - WiFi - Amazing Shower
10.0 out of 10, Exceptional, (160)
"This was exactly what we needed for our trip!! My partner and I are rock climbers, we visit this area often to climb at the Holy Boulders in Pomona, and we came up at this time to see the eclipse. Usually we camp or stay up in Carbondale, but we are already looking at coming back here for our next trip! Alto Pass is so cute and cozy, and it was so nice to come back here and recharge after long days of climbing and hiking in the woods. Steve is an awesome host, and his spot is fully equipped with...
Walk to Wineries - Quaint Village - Grill - Patio - WiFi - Amazing Shower
Stylish chalet style home
9.8 out of 10, Exceptional, (7)
"Really enjoyed our stay here. Nice and quiet and lots of room. Great kitchen and yard."
Stylish chalet style home
Betty's Vineyard House - On the Shawnee Wine Trail - Walk to/from the Winery!
10.0 out of 10, Exceptional, (67)
"What am awesome place to stay, with even better owners. Wow! How could you not love being able to WALK to Alto Vineyards AND be centrally located to all the fun things. Thank you, Beth. You're truly one of the best, and we've been renting vacation properties for 25 years!"
Betty's Vineyard House - On the Shawnee Wine Trail - Walk to/from the Winery!
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See all available properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other property types in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (114)
"The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!"
The price is $150
$244 total
includes taxes & fees
Jun 7 - Jun 8
Serenity South -- Gardens, River-Views, and Refreshing Space
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
9.6 out of 10, Exceptional, (20)
"Loved the vibe of the house. Very clean & nice."
The price is $91
$148 total
includes taxes & fees
Jun 17 - Jun 18
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Charming 2-Story- C.1847 - River Views - Fast Wifi
9.6 out of 10, Exceptional, (10)
"Cape Girardeau is about the halfway point for us (Wisconsin) and friends from Mississippi. This VRBO is ideally located within walking distance to plenty of restaurants, shops and bars. Property is very clean, has the basics and communication with the owner was super easy. The saloon-style doors for the downstairs bathroom were a little unexpected, but we made it work. We enjoyed our stay and would recommended this property for a long weekend."
Charming 2-Story- C.1847 - River Views - Fast Wifi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cape Girardeau Vacation Homes information

Number of reviews
1,260
Accommodation
42 Vacation Homes
Lowest Price
$90
Highest Price
$190

Recent reviews of Cape Girardeau hotels
Expedia verified reviews