Book an extended stay hotel in Cape Girardeau with Expedia and you’re certain to save. Along with our competitive offers and reward programs, we make finding the ideal long-term stay a cinch. Use the filters to search for properties according to location, ratings, affordability and more. Some long-term rentals may offer weekly rates to help you keep extra cash in your pocket. Often equipped with homey conveniences like a dining area and refrigerator, your next extended stay in Cape Girardeau is just a couple of clicks away!