Find 5 Star Hotels in Florence, SC
Compare Florence 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
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Rosewood Manor House B&B
Ready to experience the next standard in luxury? We know you are thinking about it. Add further enjoyment on your next trip to Florence by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Florence any longer. You'll join the multitudes of vacationers who have made Florence so fashionable in the last year. We should also mention, the hotels in this area receive high marks for guest services, so you know you'll be well cared for during your getaway. You deserve the great vacation you're dreaming about. Reserve one of our 5-star hotels in Florence and indulge in the finer things in life for a while.
5-Star Hotels in Florence
Don't be afraid to be pampered during your trip. Michelin-starred restaurants, excellent customer care, and deeply relaxing spa offerings are all on offer. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. Besides that, you'll find that these hotels are kept in great shape and provide a fine place to lay your head at night. What creature comforts do you want in your lodging? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A reflexology treatment that will leave you feeling great? Butler services? No matter what you want on a perfect getaway, you're bound to find it here.
You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Florence are waiting for you to relax after a busy day. Ready to learn more? Then explore the 560 reviews various guests have left on Expedia and get to know these places.
Make Your Escape
The results are in, and Florence 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to plan your next great escape. Select one of the 5-star hotels in Florence today and settle down in total tranquility tomorrow.
Frequently asked questions
Florence Hotels by Star Rating
Stay near popular Florence attractions
- Florence Civic Center
- Magnolia Mall
- Francis Marion University
- Mcleod Regional Medical Center
- Florence Museum
- Florence National Cemetery
- Eastern Carolina Agricultural Fairgrounds
- Palmetto Shores Lake
- Columns Plantation
- Oakdale Country Club
- Florence Veterans Park
- The Traces Golf Club
- Darlington Raceway
- Neptune Island Waterpark
- Coker College
- Florence Motor Speedway
- Dillon Motor Speedway
- Lions Park
- Beaver Creek Golf Club
- The Country Club at Lake City
More Hotel Options in Florence
- Beach Hotels (15)
- Boutique Hotels (3)
- Business Hotels (49)
- Cheap Hotels (25)
- Family Hotels (50)
- Golf Hotels (38)
- Hotel Wedding Venues (4)
- Hotel with a Concierge (3)
- Hotels & Resorts for Couples (13)
- Hotels with Air Conditioning (57)
- Hotels with Balconies (3)
- Hotels with Bars (17)
- Hotels with Connecting Rooms (15)
- Hotels with Fireplaces (4)
- Hotels with Free Breakfast (48)
- Hotels with Free Parking (57)
- Hotels with Free Wifi (58)
- Hotels with Hot Tubs (10)
- Hotels with Laundry Facilities (30)
- Hotels with Restaurants (57)
- Hotels with Room Service (4)
- Hotels with Suites (6)
- Hotels with a Gym (28)
- Hotels with a Pool (47)
- Hotels with an Indoor Pool (12)
- Hotels with an Outdoor Pool (44)
- Hotels with smoking rooms (6)
- Luxury Hotels (12)
- Non-Smoking Hotels (22)
- Pet-friendly Hotels (37)
- Resorts & Hotels with Spas (10)
- Romantic Hotels (5)
Explore more hotels
- Days Inn by Wyndham Florence/I-95 North
- Tru by Hilton Florence I-95
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an IHG Hotel
- Country Inn & Suites by Radisson, Florence, SC
- Courtyard by Marriott Florence
- Home2 Suites by Hilton Florence, SC
- Staybridge Suites Florence - Civic Center, an IHG Hotel
- Baymont Inn & Suites Florence by Wyndham
- Sleep Inn Florence
- Hilton Garden Inn Florence
- Comfort Suites Florence I-95
- TownePlace Suites by Marriott Florence
- Fairfield Inn & Suites by Marriott Florence I-20
- Best Western Inn
- Hampton Inn & Suites Florence-North-I-95
- Hampton Inn & Suites Florence Center
- SpringHill Suites by Marriott Florence
- Motel 6 Florence, SC
- Clarion Inn & Suites
- Hotel Florence, Tapestry Collection by Hilton